可约曲线

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

5Ns. The peak position of N band emission as well as the distinct emission region slightly moves towards the open end of the cylindrical cavity, and this does not happen to O band emission. Radiation transport efficiency of 6% is obtained for the φ400×1200um cylindrical cavity heated by x-ray source with radiation temperature of 118 eV.

从时间分辨的X光强度轴向空间分布来看，在较长时间（约1～1.5ns）内，O带X光在整个观测缝对应的轴向范围之内均有较大的辐射强度，在X光强度空间分布的变化过程中，其强度峰值的空间位置基本不变；而对N带X光，则只在较短时间（约0.5ns）内，在整个观测缝对应的轴向范围之内可观测到X光辐射，但只在靠近输运源约300μm的范围内有较强发射，在柱腔末端600～700μm范围之内的辐射则很弱，N带X光辐射轴向空间分布曲线的峰值位置在朝柱腔末端的方向移动，移动量大约为130～250μm。

The paper investigates both block-type pilot linear minimum mean square error algorithm and IEEE802.16 OFDM channel estimation analysis. Simulation results confirm the block-type pilot structure is more suitable for IEEE802.16 system. An optimal pilot setting algorithm, based on space frequency domain, is explored and the pilot chart is presented. The proposed algorithm finds its application in MIMO-OFDM. Simulation results show the algorithm presents a good approximation to the perfect channel state information curve, with about 2dB difference in SNR. The simulation results also demonstrate the algorithm achieves fairly high stability in the environment of fast fading, performance of the proposed algorithm is better that of pilot training channel estimation.3. Taking into account the characteristics of IEEE802.16 OFDM system, OFDM system simulation platform is constructed in Matlab, exploiting simulink as a tool. OFDM modulation and demodulation simulation system are configured on LabVIEW platform. All the system signal processing is simulated, including defining system parameters, designing modulation model, and verifying all the proposed algorithms under different environments, such as white Gaussian noise, multi-path fading, with or without guard interval etc. Bit error performance is evaluated. The research provides valid theoretical basis for practical OFDM system performance evaluation.4. Taking advantage of software radio, the paper designs a hardware platform with both 256-IFFT/FFT and 512-IFFT/FFT OFDM schemes co-existing in one platform. You can predetermine one from the two schemes to carry out almost the same model function with different system performance and parameter setting.5. Referring to IEEE802.16 standard, the paper proposes a design method for generating signals and frames suitable for laboratory investigations implemented in laboratory environment.6. Based on 6701evm digital evaluation card, combined with analogy front-end, the paper designs a DSP software model to deal with baseband signal processing. An overall OFDM scheme, with modulation and demodulation function, is accomplished.

讨论分析了MIMO-OFDM中一种基于空频域的最优导频设置算法，给出了导频图案，通过仿真实验表明，该算法与理想的信道状态信息曲线非常接近，信噪比差距约在2dB左右，并且在快衰落条件下具有较好的稳定性，其性能要优于基于前导训练的信道估计方法。3、根据IEEE802.16OFDM系统特点，论文分别在Matlab中应用Simulink工具构建OFDM系统仿真平台、在LabVIEW平台上实现了OFDM调制解调仿真系统，模拟了整个系统的信号流程，进行了OFDM仿真系统参数的选择和调制模块的仿真设计、论证各算法性能，并根据各种不同的条件：例如高斯噪声、多径衰落、有无保护间隔等，对系统的误码特性进行了评估，为正确评价实际OFDM系统的性能提供了有效的理论依据。4、论文以软件无线电思想作为指导，提出了以256点IFFT／FFT为核心和以512点IFFT／FFT为核心的两种OFDM算法模式并存于同一个硬件平台、且可预选的方案，它们在参数选取和性能指标上有所差异，均实现了相似的模块和功能。5、论文参考IEEE 802.16无线网络标准的参数设置，针对本设计系统的应用环境和系统硬件的性能速率，提出了一种应用于实验室环境的信号结构、帧格式等参数设计。6、论文基于TI公司的6701evm数字评估板卡，结合模拟前端搭建数字中频平台，设计了基带处理的DSP软件模块并进行系统调试，基本实现了一套完整的OFDM调制解调方案。

One concern is the high peak occurring in the failure cost curve at the quality of about 0.75 which can be caused by the start of a new strategy in the company.

一个值得关注的是高峰发生在失败的成本曲线在质量约0.75 ，可造成开始了一个新的策略，在该公司。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。