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The results indicate that the attenuated weight gain observed with detemir in this model can largely be attributed to a reduced increase in adiposity.

此结果表明,在这个模型中地特胰岛素治疗较弱的体重增加作用可较大程度的改善胰岛素治疗所致的肥胖。

Once anterior cruciate liament is involved in anterolateral structure injuries of the knee and Sègond fractures, expectant treatments would mistakenly lead to anterolateral rotatory instability. In such cases, enough attention should be paid to avoid missed diagnosis and misdiagnosis, and active operations should thus be performed.

膝关节前外侧结构损伤及Sègond骨折一旦累及前交叉韧带,错误地采用保守治疗,可导致膝关节前外侧旋转不稳定,临床上应予以重视,避免漏诊、误诊,积极手术治疗。

If the technology and equipment of the medical institution in the city cannot satisfy the needs of treating the member, the customer service specialist will activate the domestic transfer mechanism and arrange an ambulance or other vehicle as may be necessary under the circumstance to transfer the member from the place of first visit to the nearest suitable medical institution under the escort of a physician or nurse, with ANFA bearing the expenses incurred by the transfer (including the expenses of transport from the scene to the place of first visit).

安法会员在中国境内,因为意外伤害或突发疾病时,可协助会员安排特约医疗机构;若该城市内医疗机构的技术、设备无法满足会员治疗之条件,客服专员即启动境内转送机制,安排救护车或其他交通工具,由医师或护士陪同,转送会员从初诊地至邻近适宜的医疗机构,并承担上述转送费用以及从出事地到初诊地的运送费用,医疗转送必须由《安法24小时医疗服务中心》的医师及会员的主治医师共同认定方可启动。

Conclusion]Good results can be obtained in hips with acetabular protrusion after reconstructed with autogeneous or allogeneous bone grafting and total hip arthroplasty.

结论]应用自体股骨头骨或异体颗粒骨移植填充髋臼连系多孔生物型髋臼假体,治疗Otto's病,可获得较好的疗效,移植骨可与宿主骨很好地连系在一路。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子,CD83分子表达明显高于国内报道;肝癌患者DC培养上清中TNF水平高于健康人,提示肝癌患者DC仍具一定的抗原呈递能力,适当调控可使其行使APC功能,以期在肝癌个体化疫苗中发挥作用;DC负载肝癌可溶性抗原后,抗原呈递能力降低,BCG HSP70可促进DC成熟,增加其抗原呈递能力,预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子;肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞,活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主,同时分泌较高水平Th1型细胞因子IL-12和TNF,并抑制4种肝癌细胞生长;冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤,提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用;用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽,在体外诱导肝癌特异性淋巴细胞,活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF,并具较强杀伤活性,此CTL同时具备NK细胞特征;DC对肿瘤细胞的抑制作用可能是通过吞噬实现的,Fas-L在DC抑制中也起一定作用;DC对人肝癌裸鼠皮下移植瘤的抑制率为97%;在肝癌DC疫苗的作用中,至少联合3种以上机制,即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

There was no statistic difference of keraphyllous water changes before and after the treatment. Conclusion Intense pulse light can safely and effectively treat facial photoaging and the therapeutic efficacy is related to different anatomical sites.

强脉冲光可安全而有效地治疗面部皮肤光老化,不同解剖部位对治疗反应性不同。

Outcome:(1) Acute ischemic damage may induce the expression of c-fos protein in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia. And the expression level of c-fos can be up-regulated by putting blood of 12 hand Jing Points. So we think that treated by this therapy can rise the irritability of brain to resist the development of ischemia and enhance the ability to plerosis.(2) Acute ischemic damage may induce the expression of HspVO in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia.

三 结果(1)急性缺血性脑损伤可快速诱导c-fos蛋白在皮层缺血区脑组织的表达,其表达有随缺血时间延长而逐渐增多的趋势,提示脑的缺血性损伤可应激性地增强神经细胞对缺血、缺氧的耐受和适应能力,而应用井穴放血的干预治疗可明显上调缺血区皮层脑组织c-fos的表达水平,进一步增强脑组织对抗缺血性损伤的应激能力,抵抗缺血性脑损害的进一步发展。

Compas technique can stereoscopically display integrated and directly-perceived anatomy of the cerebral vasculature,which is of great value in guiding the interventional management and in observing the therapeutic results.

Compas可立体、直观完整地显示脑动脉瘤的病理解剖关系,对指导介入治疗或手术方式的选择和治疗效果的观察具有重要价值。

Treatment of spinal tuberculosis1methods between february 1998 and august 2000 , 12 patients with spinal tuberculosis were operated with anterior vertebrectomy , bone grafting and plating1 evaluation including bone fusionrate , correction of deformity and status of spinal lesion was carried out1results in an average of ten months ,spinal tuberculosis was completely cured and solid bone fusion had taken place in all 12 patients1 the time for bone fusion averaged 518 months and the average angle of correction of kyphosis was 16°1conclusions anterior plating following vertebrectomy and bone grafting offers a complete removal of lesion and decompression of the spinal canal as well as reconstruction of spinal stability1 early rehabilitation and an increased curative rate can be expected through this procedure1

目的 探讨经脊柱前路结核病灶清除的同时植骨内固定的可行性和必要性,以及对脊柱结核的治疗效果。方法1998 年2月~2000 年8 月采用脊柱前路病椎切除加植骨,并采用orion或z-plate 钢板进行椎体固定。共治疗12 例脊柱结核,观察植骨融合及矫正畸形情况和结核病灶愈合情况。结果经平均10 个月的随访,12 例患者脊柱结核均治愈,植骨与受骨区全部骨性融合,融合时间平均为518 个月,后凸矫正角度平均16°。全组病例切口均一期愈合。无手术并发症。结论本方法可经脊柱前路作较彻底的病灶清除,并较好地进行脊柱矫形和椎管减压,完成脊柱稳定性重建,有利于患者早期离床活动和脊柱结核治愈率的提高。

Zoic traditional Chinese medicine (Shuizhi, Dilong, Quanxie, Tubiechong) is possible to the head selection medicine to confect the iontophoresis of Chinese medicine which detumescence and acesodyne, remove the blood and silt.

1、动物类中药(水蛭、地龙、全蝎、土鳖虫)的无机元素含量相当丰富,尤其Na、Ca、Mg的含量在各类中药中居首位,可作为消肿止痛、活血化瘀中药离子导入液配制的首选用药;枝叶类和矿石类中药分别含有大量的Mn和S,可作为治疗骨与软骨损伤中药离子导入液的首选用药。

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