可接受

Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier.

药物组合物包含有效量的单独的或与一种或多种治疗活性化合物组合的本发明化合物，以及药物可接受载体。

It is a primary object of the present invention to provide an aqueous ophthalmic formulation, for treating myopia, comprising pirenzepine in combination with a pharmaceutically acceptable gel carrier.

本发明主要目的是提供一种用于治疗近视的水性眼用制剂，其含有与药物可接受的凝胶载体结合的哌仑西平。

The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient.

此处的该组合物含有一种基本上纯的至少一种邻苯二酚丁烷，包括，例如，在一种制药学上可接受的载体或赋形剂中的NDGA化合物的制剂。

It was found that an acylguanidine derivative characterized by having a tricyclic structure or a pharmaceutically acceptable salt thereof has a strong antagonism to 5HT2B receptor and 5HT7 receptor.

发现以具有三环类结构为特征的酰基胍衍生物或其制药学上可接受的盐对于5-HT 2B 受体和5-HT 7 受体都具有强力的拮抗作用。

The invention provides the application of a B vitamin, a physiologically or pharmaceutically acceptable salt of the B vitamin, a hydrate of the B vitamin or a mixture of the B vitamin, the salt and the hydrate in the preparation of a composition for controlling body weight and blood sugar and/or moderating the insulin resistance.

本发明提供了B族维生素、其生理学上或药学上可接受的盐、其水合物或它们的混合物在制备控制体重、控制血糖和/或缓解胰岛素抵抗的组合物中的用途。

The present invention is directed to substituted propylamine derivatives of formula I or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

本发明涉及式I的取代丙胺衍生物或其医药学上可接受的盐、含有这些衍生物的组合物、和其用于预防和治疗通过单胺再摄取改善的病状的使用方法，所述病状尤其包括血管舒缩症状、性功能障碍、胃肠道和泌尿生殖道病症、慢性疲劳综合症、纤维肌痛综合症、神经系统病症和其组合，特别是那些选自由严重抑郁症、血管舒缩症状、压力性和急迫性尿失禁、纤维肌痛、疼痛、糖尿病性神经病变和其组合组成的群组的病状。

Risk and maneuverability analysis on engineering design is widely used to conduct security appraisal abroad. The potential risks might be caused by technical parameter deviation, failure and faulty operation of facilities and pipelines in the system were normally analyzed along with the reason why deviation and faulty operation occurred. The acceptable risk was then appraised according to the results, reasons and designed protective facilities. Later, the security countermeasures and solutions were brought forward purposively to further modify and refurbish the security design and operation management.

国外广泛应用危险与可操作性分析对工程设计进行安全评价，分析系统中装置、设备、管道的个别部分工艺参数偏离、故障或误操作引起的潜在危险，分析偏离、故障出现的原因，根据后果、原因和已设计的保护装置，评估可接受的风险，并有针对性地提出安全对策和措施，用以指导修改、完善工程的安全设计和操作管理。

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

Based on the pyrocondensation model and principles of elasticity, the layer structure design of thin films was proposed in view of the control of residual thermal stress and the corresponding evaluation function was applied to the layer structure design of films.

基于热收缩效应模型和弹性力学原理，从薄膜膜系着手提出了控制薄膜残余热应力的膜系设计原则，将该原则的评价函数用于薄膜膜系设计中，采用优化方法可以设计出残余热应力可接受的薄膜。

This method may not be feasible if the ambient temperature conditions do not provide adequate heat to rewarm the off line container within an acceptable period of time .

如果在可接受的时间间隔内，周围温度条件不足以提供充分的热量来加热离线容器，这种方法就不可行了。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐