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Novel compounds of the structural formula are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor.

结构式化合物是大麻素-1(CB1)受体的拮抗剂和/或反向激动剂,可用于治疗、预防和抑制CB1受体介导的疾病。

The subsoiler with disc coulter can effectively restrain the evaporation of moisture in the soil, so it can be widely used in subsoiling in the corn-cover field.

带圆盘刀式深松机能有效地抑制作业后土壤水分的蒸发,可广泛用于秸秆覆盖条件下的深松作业。

The researchers said that theobromine worked by keeping down a verve activity, which cause coughing.

研究人员认为,可可碱是通过抑制可致咳的神经兴奋活动来起作用的。

Acetoin was shown to function as an inducer for the expression of aco genes, whereas glucose exhibited a repression effect.

被认定为诱导物的乙醯甲基甲醇可刺激启动区的表现,而葡萄糖则表现抑制现象。

The analgesic mechanism of yaotuilitoogsan pill is by depressing the expression of algesia neurotranamitter CORP in neurons of DRO on the non-compressive nucleus pulposus protrusion injury nerve root.

腰腿理痛散可通过下调或者抑制非机械压迫性髓核对神经根损伤后DRG内的痛觉神经递质CGRP的释放而发挥镇痛作用。

RhA can effectively prevent the information of postoperative ankylenteron by inhibiting the expression of inflammatory cytokines and reducing the inflammatory response.

大黄酸精氨酸可通过抑制炎症因子的过度表达,减轻炎症反应而有效预防术后肠粘连的形成。

The serum of Aralia chinesis can significantly inhibit NIH3T3 fibroblasts proliferation and HA synthesis, and play a certain role in anti-hepatofibrosis in vitro.

太白楤木中药血清可显著抑制MH3T3细胞增殖和HA的合成,在体外具有一定的抗肝纤维化作用。

Endostatin can inhibit the proliferation of SGC-7901 human gastric carcinoma in athymic mouse model, and the mechanism involves the suppression of Bcl-2 expression.

恩度可显著抑制裸鼠SGC-7901人胃癌的生长,可能是通过降低Bcl-2的表达而发挥其杀伤效应。

The 20-HETE-induced increases in [Ca2+]i, whole-cell L-type Ca2+ channel currents and the amplitudes of Ca2+ transients were blocked by extracellular application of chelerythrine (an inhibitor of protein kinase C, PKC) and H-89 (an inhibitor of cAMP-dependent protein kinase, PKA).

上述20-HETE诱导的[Ca2+]i、全细胞L-型钙离子通道电流、钙瞬变幅度的增加等效应,可被蛋白激酶C抑制剂白屈菜红碱和cAMP依赖蛋白激酶抑制剂H-89阻滞。

DCA-Na inhibited angiogenesis in chicken chorioallantoic membrane assay with 70% inhibition at the dose of 200μg/egg.

在200μg的浓度下DCA-Na对鸡胚尿囊膜血管形成的抑制率可达到70%。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。