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Some new sulfonamide derivatives possessing potent CA inhibitory properties act as effective in vitro tumor cell growth and metastasis inhibitors.

一些新型的磺胺类碳酸酐酶抑制剂可有效抑制体外多种肿瘤细胞系的生长和转移。

Immature dendritic cells could be used to induce suppressive antigenspecificCD4+CD25+T cells which could affect the formation of atheromatous plaques.

未成熟树突状细胞可诱导出抑制功能强大的HSP60特异性CD4+CD25+T细胞,后者在体内能明显抑制斑块的形成。

However, dexamethasooe did not seem to affect the sustained current and the sustained component of the biphasic current induced by ATP. The in hibitory effect of dexamethasonc on ATP induced currents was blocked by glucocorticoid receptor antagonist RU38486 (10μmol/L) and protein kinase A inhibitor H-89 (10μmol/L), but not by G protein inhibitor GDP-β-S (0.2mmol/L) and protein kinase C inhibitor chelerythrine chloride (10μmol/L).

地塞米松对ATP激活电流的快速抑制作用可被糖皮质激素受体拮抗剂RU38486(10μmol/L)、蛋白激酶A抑制剂H-89(10μmol/L)阻断,而G蛋白激活抑制剂GDP-β-S(0.2mmol/L)、蛋白激酶C抑制剂Chelerythrine chloride(10μmol/L)对地塞米松的快速抑制作用无明显影响。

Results 5C11 induced homotypic aggregation, proliferation arrest and apoptosis in the multiple myeloma cell line XG2 highly expressed CD40. 5C11 induced B lymphoma cell line Daudi homotypic aggregation and proliferation arrest but no apoptosis.

结果 5C11能引起CD40表达强阳性的多发性骨髓瘤细胞XG2发生同型聚集,抑制其生长并介导细胞凋亡;5C11可引起CD40+的恶性B淋巴瘤细胞株Daudi发生同型聚集,抑制其生长并使细胞发生G2/M期阻滞,但并不介导细胞凋亡。

Results Hypericin of different concentrations could significantly inhibit the proliferation and induce the apoptosis of human prostate cancer cells cultured in vitro.

结果:不同浓度的金丝桃素在体外可显著抑制PC3M细胞增殖(P.05),药物浓度为0.5、1.0和2.0 mg·L-1时,抑制率分别为21%、50%和91%;细胞周期出现S期阻滞,由S期进入M2期的比例为零,并诱导PC3M细胞凋亡。

LDL of serum in healthy person was separated by improve precipitate method.Results:Pae(300,150 mg.kg-1)could reduce significantly the levels of MDA of serum,aorta and liver;Pae(300 mg.kg-1)decreased obviously the content of OX-LDL of plasma;Pae1 000,200,40 μg.ml-1refrained markadly the course of oxidational decorate of LDL of serum in healthy person.

结果:Pae(300,150 mg.kg-1)可明显抑制高脂大鼠血清、主动脉及肝脏脂质过氧化反应;Pae(300 mg.kg-1)显著减少高脂大鼠血浆LDL的氧化修饰;Pae(1 000,200,40 μg.ml-1)对健康人血清LDL的体外氧化反应有极显著抑制效应。

These results indicate that the brain endogenous opioid system seems to play a major role in the modulation of the micturition threshold and the frequency, whereas in the spinal region, enkephalinergic neurons seem to control the activity of sacral preganglionic neurons.

这些结果显示,脑部之内吗啡系统的抑制作用,主要和排尿反射阂值之调控有关,而脊髓部位的内吗啡系统则可直接对副交感神经节前神经元造成抑制性作用。

It is suggested that the algae symbiot can affect host organellar function,quantity and location, stimulate the food uptake and digestive activity, restrain the functional activity of the organelle, change the gene expression and cause the change of genome structiure in the P. bursaria-chlorellae system.

据结果推测,纤毛虫中的藻类共生体可影响宿主细胞中胞器的功能、数量和分布,可影响细胞核核仁的数量和分布;可影响宿主细胞的形态、生长、抗氧化能力及胞质糖含量;可影响宿主细胞的食物摄取及相关胞器的消化活性,抑制宿主胞器的功能活动;并可改变宿主细胞基因的表达,导致细胞基因组结构的变化。

Cu2+ increased the activity of sucrase with the increase of Cu2+concentration below the certain level, and then appeared inhibition effects with the concentration increase above the level.

重金属离子 Ag\ Hgh、Cd卜对蔗糖酶活力的抑制作用随离子浓度增大而增加,smmol几 Ag可完全抑制蔗糖酶的活性。

Perceived by a small family of F-box proteins including transport inhibitor response 1 (TIR1), auxin regulates gene expression by promoting SCF ubiquitin-ligase-catalysed degradation of the Aux/IAA transcription repressors, but how the TIR1 F-box protein senses and becomes activated by auxin remains unclear.

植物生长素通过促进SCF复合体泛素连接酶催化的Aux/IAA转录抑制蛋白降解,可影响到包括转运抑制效应因子 TIR1在内的一个F-box蛋白小家族,但是对植物生长素如何使TIR1感应并激活仍未了解。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。