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The in vivo growth of melanoma could be controlled by OSM secreted from OSM gene-modified cells. The activated Egr-1R by radiation could enhance the expression of OSM and thereby impose an aggravated damage on tumors in vivo, namely brining a dual inhibitory effect of gene and radiation on tumors.

转基因分泌的OSM可对瘤细胞的体内生长产生抑制;射线可通过Egr-1R增强OSM表达的途径加剧肿瘤抑制,即基因与射线的双重抑瘤效果。

The experimental results indicate that oleic acid has inhibitory effect on the precipitation, and the inhibitory effect is more obvious with increasing addition of oleic acid. Specially, oleic acid of 1×10^(-5) mol/L would facilitate the agglomeration of gibbsite, oleic acid of 1×10^(-4) mol/L would inhibit the agglomeration of gibbsite.

结果表明:油酸对铝酸钠溶液的种分过程产生比较明显的抑制作用,油酸的添加量越大,抑制作用越明显;添加1×10^(-5) mol/L油酸时可促进附聚,添加1×10^(-4) mol/L油酸时抑制附聚。

When used alone, nepetalactone attracted mosquitoes to the trap of the olfactometer, however, when mixed with human odor or a L-lactic acid dichloromethane solution, nepetalactone inhibited the attractiveness obviously. Nepetalactone exhibited a spatial repellency, but was not an ideal topical repellent. DEET did not have the attractiveness to mosquitoes, and did not exhibit inhibition on L-lactic acid dichloromethane solution too, hut enhanced the attractivity of human odor to mosquitoes.

风洞定向行为测试结果表明,假荆芥内酯单独作用时,对蚊虫有微弱的引诱效果,但在人体气味及二氯甲烷L-乳酸存在时,可显著抑制这些引诱物对蚊虫的引诱效果,是优良的空间驱避剂;DEET对蚊虫无明显的引诱作用,对二氯甲烷L-乳酸溶液引诱剂也无明显的抑制效果,但可显著增强人体气味对蚊虫的引诱性。

In addition, NOS activity decreased with the time prolonged in vitro, when oxyhemoglobin, a scavenger of NO, was applied, the NOS activity kept stable. This result above demonstrated that NO can inhibit NOS activity, and it was the inhibition of NOS activity by NO that may be an important protective mechanism to resist the neurotoxicity by Py.

另外,本实验还发现,在体外实验时,一氧化氮合酶活性可随时间的延长而逐渐下降,当向反应体系中加入氧合血红蛋白去除一氧化氮的作用后,则一氧化氮的抑制作用消失,酶活性保持稳定;以上结果表明一氧化氮对于一氧化氮合酶活性具有抑制作用,而且这种抑制作用,可能是机体对抗拟除虫菊酯毒性作用的一种重要保护机制。

SAB can inhibit the proliferation of rat primary cultured hepatic stellate cells by suppressing the expression of PDGF receptor, which is associated with the antioxidant effect of SAB.

SAB可通过抑制PDGFR的表达而抑制体外培养HSC的增殖,这种抑制作用与SAB的抗氧化作用有一定的关系。

Fluid of profess to convinced of glue of result compound bee can restrain the formation of reserpine ulcer significantly, the heal of acerbity to second burn ulcer has apparent stimulative effect, can restrain the formation of pylorus ligate ulcer significantly, reduce cankerous area significantly, its action and positive contrast medical Xi Mi comparatives for man.

结果复方蜂胶口服液可显著抑制利血平溃疡的形成,对乙酸烧灼型溃疡的愈合有明显的促进功能,可显著抑制幽门结扎溃疡的形成,并显著减少溃疡面积,其功能和阳性对照药西咪替丁相当。

Results The levels of HSP 70 mRNA and HSP 70 protein expression were significantly different among the 5 groups. Ketamine induced marked HSP 70 mRNA and HSP 70 protein expression in the posterior cingulated cortex. Propofol itself did not induce HSP 70 gene expression in this brain region. Propofol significantly inhibited ketamine-induced HSP 70 mRNA and HSP 70 protein expression in the posterior cingulate cortex in a dose-dependent manner.

结果氯胺酮可明显诱导HSP70 mRNA与HSP70蛋白在大鼠后扣带回皮质区的表达;异丙酚自身不能诱导HSP70基因的表达;预先给予异丙酚可显著抑制氯胺酮诱导的HSP70 mRNA和HSP70蛋白在这一区域的表达,且抑制效应呈剂量依赖性。

Result 1 Magnetic nanoparticles, magnetic nanoparticles modified with antisense oligodeoxynucleotide of human telomerase reverse transcriptase induced HL-60 tumor cells to apoptosis, we could see typical morphologic change of apoptosis cells: karyopyknosis, chromation"s condensing and aggregation in nuclear, forming crescent-shaped or annulus structures to lean on edge of cell nucleus"s membrane and posing apoptosis body by Atomic Force Microscope, Fluorescence microscope, transmission electron Microscope 2 There was a significant difference compared with control group(p.01), inhibition ratio had significant positive correlation with medication dosage and time ;during 0.8-8μM dosage amplitude, inhibition ratio accrescenced by dosages increasing. However, the inhibition ratio would decrease when dosage over 8-80μM.

结果 1 磁性纳米粒子、修饰有端粒酶反义寡核苷酸的磁性纳米粒子诱导HL-60细胞发生凋亡,原子力显微镜、光学显微镜、荧光显微镜和透射电镜下均观察到HL-60细胞呈现典型的凋亡细胞的形态变化:细胞核固缩,核内染色质浓缩、凝聚、形成新月形或环状结构紧靠在细胞核膜边缘,并形成凋亡小体。2 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子对HL-60肿瘤细胞的生长和增殖有明显的抑制作用,与对照组相比有显著性差异(p<0.01),在剂量为0.8-8μmol/L范围内,抑制率随剂量的增加而增加,当剂量超过8μmol/L时,抑制率反而下降;3 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子可增强p53基因的表达活性,引起DNA降解损伤,反向调节细胞周期活动,促使细胞从G0期进入G1期,抑制肿瘤细胞的生长。4 修饰有端粒酶反义寡聚脱氧核苷酸的量子点能通过内吞作用进入HL-60肿瘤细胞的细胞核,可以在细胞内进行定位和促进HL-60肿瘤细胞的凋亡。

Benzoate (400 mg/kg) or creatinine (400 mg/kg), two inhibitors of DAAO, blocked D-NNA-induced pressor responses in rats. Furthermore, the addition of the pure DAAO significantly potentiates L-NNA production rate in kidney homogenates by approximately 2-folds. The in vivo and in vitro results suggested that DAAO plays an essential role in the pressor responses elicited by D-NNA.

体内实验显示,DAAO的选择性抑制剂苯甲酸钠(400mg/kg)或肌酐(400mg/kg)均可在不同程度上抑制D-NNA升压作用,进一步研究发现,肾脏或肝脏DAAO酶液在外加DAAO后可提高D-NNA的手性转化约2倍,表明DAAO对于D-NNA在体内的手性转化是必需的。

Under the experimental conditions, alum, alum/sodium silicate, sodium silicate/hydrochloric acid, zinc chloride, and sodium silicate/zinc chloride are effective to inhibit the dissolution of precipitated calcium carbonate in distilled water with pH value 5.85, and the pH values of the suspensions decrease.

硫酸铝、氯化锌、硅酸钠/稀盐酸可对PCC在pH值为5.95的醋酸/醋酸钠缓冲溶液中的溶解性产生较弱的抑制作用,硅酸钠/氯化锌的溶解抑制作用相对较为显著,滤液钙离子浓度可降低30%左右。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。