可导致的

Literature Research The etiological factors of POF are not still clear. The changes of sites and numbers in X chromatosome, X; autosome translocations, a forkhead transcription factor gene (FOXL2) mutations, FRAXA premutations and inhibits gene mutations are found in POF patients, so genetic disorders have been thought to be involved. Irradiation, chemotherapy or pelvic operations can damage ovaries and cause ovarian atrophy and failure, so it is thought one factor of POF.

一、文献研究 POF的确切病因目前尚不清楚，从POF患者体内检测到X染色体上位点和数目的变化，X染色体与常染色体间的平衡易位，脆性X基因前突变，FOXL2基因突变，抑制素基因突变等，故认为POF发生与遗传因素有关；由于放射、化疗或盆腔手术等可损伤卵巢，导致卵巢萎缩，出现卵巢衰竭，故也是导致POF的因素之一。

On such day: there develops, occurs, exists or comes into force any event whereby in the reasonable opinion of the Underwriter, the success of the Open Offer or the business or financial condition and/or prospects of the group would, might be or is likely to be adversely affected or which makes it inadvisable or inexpedient to proceed with the Open Offer; or there comes to the notice of the Underwriter or the Underwriter shall have reasonable cause to believe that any of the undertakings or other obligations expressed to be assumed by or imposed on the Company under the underwriting agreement have not been complied with in any material respect; or there comes to the notice of the Underwriter or the Underwriter shall have reasonable cause to believe that any of the representations or warranties given by the Company under the underwriting agreement was untrue, incorrect, misleading or inaccurate in any material respect which adversely affect the success of the Open Offer; which in the reasonable opinion of the Underwriter: is or may or will be or is likely to be adverse to, or prejudicially affects, the business or financial or trading position or prospects of the group taken as a whole; or is or may or will be or is likely to adversely affect the success of the Open Offer and/or makes it impracticable, inexpedient or inadvisable for any part of the underwriting agreement and the Open Offer to be performed or implemented as envisaged; or make or will or is likely to make it impracticable, inexpedient or inadvisable to proceed with the Open Offer or the delivery of the convertible non-voting preference shares on the terms and in the manner contemplated by the Prospectus or the underwriting agreement.

Samson Paper Holdings Limited Provisional Allotment Account 倘于接纳可兑换无投票权优先股份及付款的截止时间后两个营业日下午六时正前任何时间出现下列事件，则公开发售包销商Quinselle Holdings Limited可于该日期下午六时正前任何时间向本公司发出书面通知以终止包销协议：因任何事件之出现、发生、存在或生效而令包销商合理认为将会、可能或极大机会对公开发售能否顺利进行或本集团之业务或财政状况及╱或前景构成不利影响，或致使进行公开发售实属不合理或不合宜；或包销商注意到或包销商有合理理由相信本公司并无于所有重大方面遵守根据包销协议列明须承担或获委予之任何承诺或其他责任；或包销商注意到或包销商有合理理由相信本公司根据包销协议作出之任何陈述或保证于任何重大方面属失实、错误、误导或不准确而对公开发售能否顺利进行造成不利影响；而包销商合理认为：经已或可能或将会或大有可能对本集团整体业务或财政或经营状况或前景造成不利影响或损害；或经已或可能或将会或大有可能对公开发售能否顺利进行构成不利影响及╱或使持续进行使包销协议的任何部份或公开发售的进行或落实为不实际、不合适或不合宜；或按发售章程或包销协议拟订之条款及方式持续进行公开发售或寄发可兑换无投票权优先股份导致、将为或大有可能为不实际、不合适或不合宜。

Quantum effects in Si n-MOS inversion layer at high substrate concentration. Solid-State Electron, 1990, 33(12): 1581～15854 Van Dort M J, Woorlee P H, Walker A J, et al. Influence of high substrate doping levels on the threshold voltage and the mobility of deep-submicrometer MOSFET's.

结果表明：在高衬底掺杂浓度时，即使在弱反型区量子化效应也能导致载流子分布和电流产生明显的降低(例如： 1.5×1018 cm-3时，可降低一个数量级以上)，从而导致开启电压的升高。

In such cases a resulting contract may be voidable because of fraud, duress, mistake, or other invalidating cause.

在这种情况下产生的合同可能因为欺诈，胁迫，错误，或者其他导致可撤销原因而成为可撤销合同。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

Diabetes incidence of the disease process, as Yin Huo can filth, but also gas consumption, leading to the bion Diabetes is a deficiency disease Machine important stage.

消渴病发生发展过程中，由于阴虚火旺，既可伤阴，又可耗气，最终导致气阴两虚，气阴两虚是消渴病病机的重要阶段。

Jq Ez6_{0An outbreak of highly pathogenic avian influenza caused by H5N1 virus occurred in Vietnam, Japan and Korea, commencing in December, 2003. By February, 2004, it has been distributed widely in Asia and brought heavy losses. H5N1 are ball-like RNA viruses, birds can shed them via respiratory system, ocular secretions and feces, sometimes transferred to human and cause lethal infection. H5N1 patients have prominent features of reactive hemophagocytic syndrome,bronchiolar inflammation, necrosis of bronchial epithelium and organizing,diffuse alveolar damage with interstitial fibrosis.

2003年12月，H5N1型禽流感病毒在越南、日本和韩国爆发，到2004年2月，该病毒已在亚洲广泛蔓延并带来了巨大损失。H5N1是球型RNA病毒，禽类间可通过呼吸系统、眼分泌物和粪便传播，也可传染人类甚至导致死亡。H5N1感染者的特征是反应性噬血细胞综合征、细支气管炎症、支气管上皮坏死和机化、弥漫性肺泡病变和间质纤维化。

The main characteristics include: the quiet Sun corona has a rapid response to the flare heating, within 2 second the corona temperature increases nearly one order of magnitude, but later such increase becomes very slowly; the downward velocity at early stage of impulsive phase is too small to be negnected; chromospheric evaporation made by conduction shows some intensely, the maximum evaporated velocity may be as large as 1000 km/s; the chromospheric condensation appears just when the chromospheric evaporation takes place and its place always coincide with that of transition region in the early stage; the maximum of chromospheric condensation occurs also in the early stage of impulsive phase, at which the density in condensation may be larger two order of magnitude than that of surround and the downward velocity may be as large as 100 km/s; after the maximum of chromospheric condensation, its strongth decreases gradually but its width becomes greater with time and have a tendency to transport into deep chromosphere; the front of chromospheric condensation heats atmosphere obviously and the temperature in the chromospheric condensation is higher than the original case; the downware velocity of transition region may be greater than 100 km/s at the early stage; when the evaporated material collide at the top of loop, the densityand the presure there increase rapidly, which result in the formation of a shock wave; and so on.

在改善色球辐射损失和精确分辨过渡区的基础上，通过联立求解连续性方程、动量方程和能量方程，构造了一维磁限制性耀斑环在热沉积作用下的大气动力学模型，获得了耀斑热模型下脉冲相早期较为细致的大气演化理论图象，其主要特征是：耀斑对宁静日冕的加热相当迅速，仅2秒钟日冕温度增加即达一个量级，之后日冕温度增加缓慢；脉冲相早期日冕向下速度很小，几乎可以忽略，热传导驱动色球蒸发，其过程较为激烈，蒸发极大速度可达到1000km/s；色球压缩区与色球蒸发几乎同时形成，且在早期其位置总是与过渡区位置重合；色球压缩极大发生在脉冲相早期，其时密度可高于周围约2个量级，向下速度可超过100km/s；色球压缩极大后，其强度逐渐减弱，但宽度明显增大，且渐渐脱离过渡区往色球传播；压缩区内物质温度要高于原先的大气温度；过渡区下降在脉冲相早期相当迅速，可超过100km/s；当蒸发物质在环顶高速相碰时，环顶的密度、压力迅速增大，且温度也有所增加，导致形成激波，其波面以每秒上百公里的速度自环顶向下传播；在脉冲相前期，日冕软x辐射对色球的加热作用可以忽略；等。

Mother with this disease whose baby may infect diffuse pyoderma , with symptom of excoriation , so it often be considered as congenital syphilisby mistake .

孕妇感染后可引起胎膜早破而导致早产，患病母亲所生小儿可患有弥漫的脓皮病，表皮脱落，常被误认为是先天梅毒。

Equipment life is extended by preventing machinery jams and saw blade de-alignment, as well as lockup causing equipment stress.

使用软启动器可防止机械卡夹、锯条错位及导致设备应力的闭锁因而延长设备寿命泵失速或卡泵时软启动器可防止设备损坏。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。