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Importantly, T cells engineered to express a rapamycin-resistant mTOR construct are resistant to anergy induction caused by rapamycin.

重要地是,T细胞表达人为构造的耐受雷帕霉素mTOR可对抗雷帕霉素诱导的无能。

NOS inhibitors and Dyn might produce cooperative down-regulation on the function of NMDA-NOS pathway in dorsal cord.

NOS 抑制剂可对抗 Dyn 的致瘫作用,并且与 Dyn 协同下调脊髓背侧 NMDA-NOS 通路的功能。

Intraventricular injection of TRH, a well known vagal center excitator, potentiated the indomethacin induced ulcer and reversed the action of bombesin.

此外,将具有兴奋迷走中枢作用的促甲状腺激素释放激素注入侧脑室可明显地加重溃疡,并可对抗蛙皮素减轻溃疡的作用。

Een though researchers understood that PA-457 seemed to hae actiity against all strains of HI, they needed to find out how the betulinic acid deriatie worked against the irus on the molecular leel.

研究人员了解到PA-457似乎可对抗所有品系的HI后,还需要知道桦木酸的衍生物在分子层次上怎样对付病毒。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果,本论文首次提出以下论点:(1)ACTH在脊髓水平对抗阿片镇痛具有受体选择性,即ACTH可对抗μ受体和δ受体介导的镇痛,不对抗κ受体所介导的镇痛;(2)由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力,与μ受体的非肽类配体的结合位点以及δ受体无亲和力,推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的;(3)ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用;(4)ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应;(5)通过Fos蛋白的诱导揭示:ACTH可以作用于脑内多个核团,其中包括许多与痛觉调制有关的核团,推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

Monbiot views growth is "a political sedative, snuffing out protest, permitting governments to avoid confrontation with the rich, preventing the construction of a just and sustainable economy".

monbiot意见的增长是&一个政治镇静, snuffing出来抗议,允许各国政府,以避免对抗与丰富,防止建设一个公正和可持续的经济&。

Results: Xuesetong protected the acute myocardial injury in rats by ligaturing the left descending coronary artery and reduced myocardial infarct range. Xuesetong decreased the CPK, LDH and the production of MDA, improved the activity of SOD in myocardium.

结果:血塞通可对抗结扎大鼠冠状动脉左前降支所致的大鼠急性心肌损伤,使心肌缺血大鼠的CPK及LDH降低,并可增加心肌组织SOD的活性,减少MDA生成且能显著缩小心肌梗死的范围。

In 16 month- aged mice, TP (50, 200mg/kg, ig) also showed potentiating effect on PFC response.

TP(200,400mg/kg,ig)可促进正常小鼠的PFC反应,并可对抗环磷酰胺(10mg/kg ip)和冷水(14±1℃)游泳应激所致的PFC反应降低;TP(50.200mg/kg)可使16月龄老年小鼠低下的PFC反应恢复至正常3月龄年轻小鼠水平。

Add in realistic voice acting, and you're about to get emotionally attached toa whole platoon of charactersEvery object on the battlefield is destructible - and once it's destroyed, it stays destroyedIn addition to the rich 1-player storyline, Pathway to Glory features the kind of multiplayer options that N-Gage was made for: go against another player using the same game deck with the Hot Seat option, or connect via Bluetooth technology and go head-to-head.

在现实的声音演戏方面增加,而且你正要拿个性的整个排给在情绪上附上的 toa在战场上的每个物体是可破坏的-而且一经资讯科技被破坏,它停留破坏发现你站着哪里:钮扣的推给你一个概览,如此你能很快地恢复一种不稳定的情形控制除了富有的 1个运动员的剧情之外,通往光荣的道路以可多人玩的选项类型为特色 N-规格被有益:去对抗和困境选项一起使用相同的游戏甲板的另外一个运动员,否则经由 Bluetooth 技术连接而且去头-到-头。

Such MCF-7 cells were then cocultured with TILs isolated from fresh tumor samples and their apoptosis was assessed by JAM test. Results ...

BCL - 2表达的乳腺癌细胞可对抗肿瘤浸润淋巴细胞的免疫攻击,BCL - 2SON可作为治疗乳腺癌的新途径。

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Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车,和一双合并为一移交&整个lotta爱&。

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这是凯特,那个是爱朗。

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明确的宗旨,目标和重点战略业务计划。