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The blood pressure of.1 of pathology physiology mechanism that SAS causes CVD breathes time-out to be able to bring about airframe in elevatory Morpheus anoxic, sympathetic is excessive and excited, element of serous catechu phenolic amine, kidney and hemal endodermis element are elevatory, bring about hemal easy of hemal convulsion; to shrink the function is disorder, can make blood-vessel flowing flesh happening reframes and fleshy, systemic blood-vessel obstruction adds element of the kidney when; is chronic and anoxic, system of hemal and nervous element is activationed, bring about blood pressure to lift. Obstruction of way of energy of life of patient of OSAS of disease of blood of 1.2 low oxygen increases, cause air current to interrupt, breath pauses, at the same time airframe gets used to low oxygen environment gradually, breathing centre drops to low oxygen and sensitivity of disease of blood of tall carbonic acid, breath suspends a frequency increasing, farther aggravating airframe is anoxic. 1.3 heads are self-adjusting the function drops normal person changes quickly in systematic circulation blood pressure when, the head can be passed adjust independently functional generation protects effect, make change of cerebral blood flow not big.

SAS诱发CVD的病理生理机制。1血压升高睡眠中呼吸暂停可导致机体缺氧,交感神经过度兴奋,血浆儿茶酚胺、肾素以及血管内皮素升高,导致血管痉挛;血管舒缩功能紊乱,可使血管平滑肌发生重构和肥厚,全身血管阻力增加;慢性缺氧时肾素—血管紧张素系统被激活,导致血压升高。1.2低氧血症OSAS患者气道阻力增加,造成气流中断、呼吸暂停,同时机体逐渐适应低氧环境,呼吸中枢对低氧和高碳酸血症敏感性下降,呼吸暂停次数增加,进一步加重机体缺氧。1.3脑自动调节功能下降正常人在体循环血压快速变化时,脑可通过自主调节功能产生保护效应,使脑血流量变化不大。

In the one half part, according to the strontium nature, thermodynamic calculation of correlative reaction and the principle of the vacuum aluminothermy reduction process, with the laboratory findings of preparation strontium by vacuum aluminothermy reduction compared and analyzed in different parameter conditions, a variety of factors which effect the decomposition rate of SrCO_3 and the percent reduction of strontia are gotten out. The factors include that the decomposition rate of SrCO_3 is influenced by different addition and pressure. They also include that the percent reduction of strontia is influenced by excess coefficient of reducing agent aluminium powder, the particle size of raw material or reducing agent, the pressure of barbecuing, temperature and reduction time. According to those, we can draw the conclusion as follows:(1) Decomposition temperature of SrCO_3 is decreased by adding carbon and alumina in different degree.(2) With quantitative carbon added under the vacuum condition, the decomposition temperature of SrCO_3 is decreased obviously, which can fall 150℃ compared with atmospheric pressure.(3) In keeping 1150℃ of 2.5h, under the 5Pa vacuum condition, the decomposition rate of SrCO_3 nearly keeps in 99% steadily.

在前半部分的真空铝热还原法中,根据锶的性质、相关反应的热力学计算及真空铝热还原法原理,通过对不同参数条件下的真空铝热还原法生产金属锶的实验结果的分析比较,得出了影响SrCO_3的分解率和氧化锶的还原率的种种因素,具体因素包括不同添加剂、不同气压对SrCO_3分解率的影响,还原剂铝粉的过量系数、原料与还原剂的粒度、制团压力、温度和还原时间等对氧化锶还原率的影响,得出具体结论如下:(1)添加碳和Al_2O_3能不同程度的降低SrCO_3的分解温度;(2)真空条件下加入一定量的碳可显著降低SrCO_3的分解温度,比之常压下可降低150℃之多;(3)在1150℃恒温2.5h、真空度达到5Pa的条件下,SrCO_3的分解率几乎保持稳定在99%;(4)氧化锶的还原率随还原剂过量系数的增大而增大,但是趋势越来越小,当过量系数超过25%后,氧化锶的还原率几乎不再增加;(5)氧化锶的还原率随原料与还原剂的粒度的变细而增加;(6)氧化锶的还原率随制团压力的增加而增加,但超过一定值后,氧化锶的还原率反而会下降;(7)氧化锶的还原率随还原温度的升高而增加;(8)氧化锶的还原率随还原时间延长而增加,在本实验条件下,超过2.5h趋于稳定。

Added the current connection system icon on the top bar.

v1.22更新:-显示约会项目增加到最高6条-增加设置更改显示未来多少天内的约会-增加设置更改约会显示的日期格式-点击约会详细会临时缩短约会显示为1,再次点击可恢复-增加全屏电池状态的显示设置(可设置充电中显示/不显示/总是显示)-标题栏增加当前连接系统图标-增加:当笔触离开时解锁(仅对Diamond有效)-再次修复在一些设备上无法显示约会的问题-再次修复在一些设备上导致的偶然性的额外电量消耗问题-再次修复唤醒设备时S2U2无法聚焦的问题-修复了一些小问题原文如下

Cd〓 (1, 10, 100, 1000μM) stimulated directly GtH secretion from pituitary of common carp in vitro, with the highest GtH secretion at 100μM, GtH secretion stimulated with 1000μM Cd〓 was not higher than that stimulated with 100μM Cd〓.The antagonism between Ca〓 and Cd〓 in perfusion of the pituitary fragments was not obvious.After being preperfusion with 100μM Cd〓(with or without Ca〓), the GtH secretion of the pituitary fragment was irresponsive to 2-min pulse stmulation of 10μM sGnRH-A.

鲤鱼脑垂体碎片离体灌流孵育实验结果显示,Cd〓(1,10,100,1000μM)可直接刺激鲤鱼脑垂体分泌GtH,灌流液中Ca〓对Cd〓的拮抗作用不明显,100μM Cd〓刺激脑垂体分泌GtH达到高峰,Cd〓浓度增加到1000μM时,脑垂体分泌GtH并没有进一步增加,甚至有减少的趋势;100μM Cd〓预灌流脑垂体后,可使脑垂体对2-min 10μM sGnRH-A刺激的反应性消失;1.25mM的EDTA可消除100μM Cd〓刺激脑垂体分泌GtH的作用;TFP和Cd〓同时灌流脑垂体一段时间后,撤除TFP可使脑垂体分泌GtH显著增加,即出现"反跳"现象。

Fruit yields, weight of single fruit, per fruit pulp weight, fruit edible ratio, water content of sarcocarp were all increased with the increase of SWC and reached the maximum at SWC75. Soluble brix, soluble suger and titratable acid of fruit had notable or significantly notable negative-linear relations with SWC (R~2 = 0.880 7*; R~2 = 0.717 7* and R~2=0.965 1**) while pH of fruit was increased as SWC did. Brix-acid ratio of fruit was increased linearly with the increase of SWC (R~2=0.908 6*, n=50) and reached the maximum at SWC75. Suger-acid ratio also increased with SWC.

在SWC≤75%时,柑橘产量,单果重,单果果肉重、果实可食率、果肉含水量等随SWC增加而显著增加,在75%时各指标值最高;果实可溶性固形物、可溶性糖和可滴定酸含量分别与SWC呈显著或极显著线性负相关,相关系数分别为R~2=0.880 7~*(n:50)、R~2=0.717 7~*(n=50)和R~2=0.965 1~n=50果实pH值则呈相反趋势,柑橘果实固酸比和糖酸比随SWC的增加而显著增加,果实固酸比与SWC呈显著线性相关(R~2=0.908 6~*,n=50,糖酸比在SWC=75%时达到最大值。

As a whole the effective assess ment index of intraoperational monitor had been established, providing reference for the lumbar spondylolisthesis surgery.Taking the SEP index value of postanesthetic patients before operation as the standard, the changes of intraoperational potential may indicate the following status: The latency period decreasing in 10%-15% or the amplitudes increasing in 40% indicated that the outlook of recovery was good enough and the prognosis was favoured.The latency period decreasing in less than 10% or the amplitudes increasing in less than 30% indicated that part of the function could be reduced.

以患者术前以及麻醉后的SEP指标值为基础,术中监测电位指标变化表现形式:①滑脱复位后,若潜伏期缩短10%~15%或波幅增加>40%,提示预后良好;②监测电位指标平稳,或潜伏期缩短<10%,或波幅增加<30%,可继续完成复位,术后可有部分功能恢复和症状改善;③在复位过程中,监测电位指标出现暂时性波动,可在15~20min内恢复到基础电位,应在电位出现波动时停止复位,术后仍可恢复部分功能和改善症状。

In order to cater the generalization of shuttleles looms and hi-efficient production and upgrading the general quality of the knitting yarn,analysis is done to the impact of the snicks of the knitting yarn and the special structure of the knitting fabric before highlight is given to the main cause leading to snicks of resultant yarn and to the technological counter-measures against the snicks.

为了适应无梭织机普及和高效率生产的需求,提高针织纱整体质量,在分析针织纱成纱细节疵点危害性及针织物独特组织结构要求的基础上,重点阐述了成纱细节疵点产生和增加的主要原因及降低成纱细节应采取的相关技术措施,指出通过采用合理的配棉,优选前、后纺工艺参数,保持良好的设备状况,合理选用新型优质的纺纱专件、器材,强化日常性的操作与清整洁工作,重视各工序的温湿度管理,可明显减少针织纱的细节疵点,提高成纱质量的整体水平。

Experiments of bioremediation and control were conducted with the alkali meadow grass planted in saline soil for 3 years. Contrasted with control group, topsoil desalination rate was up to 77.00%; pH value decreased 0.25 pH unit; soil bulk density decreased 0.14 g/m^3; total porosity increased by 5.29%; soil aggregate structure increased by 23.14%; soil water content increased 70.30 g/kg; average triennial alkali grass yield was 36000 kg/hm^2. In addition, planting forage in saline soil as a medium and establishing a compound agro-forestry-animal system promoted the sound combination of planting industry, forestry, and livestock husbandry. Because of the reasons, utilization ratio of land reached more than 184.00%; the income of land increased from 16300 to 35500 yuan/hm^2 average income per farmer in the controlling region increased by 66.00%, from 2160.70 to 1300.80 yuan.

生物修复与调控试验研究表明,草甸盐土经种植碱茅草3a,耕层土壤与对照相比脱盐率达77.00%,pH值下降了0.25个单位,容重降低0.14g/立方公尺,总孔隙度增加5.29%,团粒结构增加了23.14%,自然含水量增加70.30g/kg.3年生碱茅草平均产草量36000 kg/hm^2;盐化耕地采用以种植牧草为中介,将种植业与农区林业、畜牧业有机结合成互相依存,互相促进的农林牧复合生物系统治理后,土地利用率可达184.00%以上,可获得16300~35500元/hm^2的经济收入,治理区农户人均纯收入由1300.80元增加到2160.70元,增加了66.00%。

RESULTS:(1) ET-1 could increase total protein production, surface area, ERKs activity and [Ca2+]i in cultured cardiomyocyte in dose-dependent manner at concentrations ranging from 10-9 to 10-7 mol/L. And this effect could be abolished by BQ123, an antagonist of ETA receptor, partly inhibited by PTX, but not by BQ788, an antagonist of ETB receptor.(2)The activation of ERKs and the increase of [Ca2+]i induced by ET-1 were obviously inhibited by PD98059, a selective ERKs kinase inhibitor, and nifedipine, a calcium channel blocker, respectively. Both antagonists partially inhibited ET-1-stimulated cardiomyocyte hypertrophic response.(3) Staurosporine, a selective PKC inhibitor, could inhibit ET-1-stimulated cardiomyocyte hypertrophic response and increase of [Ca2+]i, but not affect the activation of ERKs.

结果: ①ET-1浓度依赖性增加新生大鼠心肌细胞蛋白质含量和心肌细胞表面积、ERKs活性及[Ca2+]i浓度,以上作用可被ETA受体拮抗剂BQ123所完全抑制,被百日咳毒素部分抑制,而ETB受体拮抗剂BQ788则无效;②ERKs激酶特异性抑制剂PD98059可完全抑制ET-1激活ERKs的作用,钙通道拮抗剂硝苯地平可明显抑制ET-1介导的[Ca2+]i浓度增加,但二者皆仅部分抑制ET-1介导的心肌细胞肥大反应;③蛋白激酶C选择性抑制剂staurosporine并不能明显抑制ET-1介导的ERKs激活,但可抑制ET-1介导的的[Ca2+]i浓度增加及心肌细胞肥大反应。

Highly active, small-molecule furin inhibitors are attractive drug candidates to fend off bacterial exotoxins and viral infection. Based on the 22-residue, active Lys fragment of the mung bean trypsin inhibitor, a series of furin inhibitors were designed and synthesized, and their inhibitory activity toward furin and kexin was evaluated using enzyme kinetic analysis. The most potent inhibitor, containing 16 amino acid residues with a Ki value of 2.45×10~(-9) M for furin and of 5.60×10~(-7) M for kexin, was designed by three incremental approaches.

本论文研究活性多肽类似物的设计、制备和功能,分为四个部分,采用多肽固相和液相合成的方法,分别合成了活性多肽绿豆胰蛋白酶抑制剂Lys片段长链16肽、天花粉胰蛋白酶抑制剂、癌胚抗原肽、甜味肽等一系列类似物,并测定了这些类似物的生物活性,有以下新的研究结果:1、furin酶抑制剂的设计、制备和功能;2、芳香氨基酸芳环之间的π-π共轭能部分补偿二硫键的作用;3、癌胚抗原肽Gly4被L-Pro替代可增加与HLA-A2分子的结合;4、肽键对甜味肽保持甜味是必须的。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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