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Such as inflammation of joints, the lower leg, such as chronic venous insufficiency lead to long-term sustainability of the skin caused by congestive hairy; hyperthyroidism in Pretibial myxedema patch Department often long acuminatum out; hypothyroidism and limbs of children in the back outside a large number of hair growth; children with viral encephalitis and inter-brain barrier after mumps-induced systemic hairy; head injury, especially after the children more prone to hair; children with primary malnutrition or enteropathy, or other malabsorption, or severe infections caused by malnutrition could rise to a large number of multi-body hair; anorexia nervosa patients in the face, trunk and upper limbs have more hair grow; infant limb pain patients in the limbs, face, trunk and more hair; dermatomyositis patients, mainly in children can be located hairy forearm, leg and temporal, but also a broader scope; Berordinelli syndrome, that is, growth and maturity accelerated from an early age, and accompanied by malnutrition and intestinal muscle atrophy, common hepatomegaly and high blood fat, the skin of patients with rough, often hairy; addition of certain drugs such as streptomycin, such as cortisone can cause iatrogenic hairy; some women as a result of adrenal, ovarian and other diseases caused by increased androgen can also result in more hair.

如炎症性关节,小腿慢性静脉机能不全等导致长期持续的皮肤充血造成多毛;甲状腺机能亢进者在胫前粘液性水肿的斑块处常有粗毛长出;甲状腺机能减退的儿童背部和四肢外侧有大量毛发生长;儿童在病毒性脑炎及流行性腮腺炎后间脑障碍所致的全身性多毛;头部外伤后特别是儿童易发生多毛;儿童原发性营养不良或肠病,或其他吸收不良,或严重感染引起的营养不良均可引起大量全身性多毛;神经性厌食症患者可在面部、躯干和上肢有较多的毛发长出;婴儿肢痛病患者可在四肢、面部、躯干部多毛;皮肌炎患者,主要发生于儿童中,多毛可位于前臂、小腿和颞部,但范围也更广泛;Berordinelli综合征,即生长和成熟从小就加速,并伴有肠营养不良和肌肉萎缩,常见肝肿大和高血脂,其患者皮肤粗糙,常多毛;此外某些药物如链霉素、可的松等可造成医源性多毛;某些妇女因肾上腺、卵巢等疾病致雄性激素增多也可造成多毛。

The conclusions were as follows: theνO-H andνC=O IR absorption maxima shifted towards higher wave numbers after imprinting 17β-estradiol on TFMAA-co-TRIM copolymer with the red shift of theνO-H groups being apparent after precipitation polymerization for 16h while that forνC=O groups being observed after polymerization for 24h. A strong interaction between TFMAA and 17β-estradiol was confirmed by the high selectivity for 17β-estradiol, as indicted by the values of the separation factor of isomers of 17β-estradiol/17α-estradiol (2.28) and the imprinted factor (3.01). Particle diameter of TFMAA-co-TRIM polymer was between 300 nm and 1.5μm, which suited well for solid phase sorbent throughout at low column pressure. The recognition of imprinting TFMAA-co-TRIM polymer for sterol molecules was driven by enthalpy eluted with acetronitile, and low temperature was in favor of the separation of sterol structure analogues on imprinting column. TFMAA-co-TRIM polymer possessed of determinate anti-heat stability, with melting point beginning at 255.84℃, Tp=257.40℃, control TFMAA-co-TRIM polymer and imprinting TFMAA-co-TRIM polymer were respectively decompounded at 267.79℃and 343.11℃, and solid micro-extraction noddle prepared by the special polymerization also showed definite recognition for 17β-estradiol by GC/MS detecting at 270℃. By selection of various washing and elution solvents, elution reagents of close polymerization system were of more advantage in template molecules retention and recognition on molecularly imprinted solid phase extraction column. At a certain extent, progesterone, 17α-estradiol, 17β-estradiol and 4-androstene-3, 17-dione could be intercepted on the MISPE column. Especially, MISPE had high selectivity for progesterone, and imprinting TFMAA-co-TRIM polymer could achieve adsorption balance within 50 min by absorption kinetics test for 17β-estradiol. However, MISPE column showed better selectivity and enrichment property for 17β-estradiol than C18 and CSPE columns according to the data from HPLC and GC/MS analyses. Recovery of 17β-estradiol on MISPE column was up to 85.5% while when prime extracting solution of milk powder was sampled, the recovery of CSPE and C18 columns were 43.7% and 30.7%, respectively.

通过研究阐明:紫外聚合产物TFMAA-co-TRIM中的νO-H振动吸收峰在聚合16h后红移,νC=O振动吸收峰在聚合24h后红移;TFMAA-co-TRIM对雌二醇异构体的印迹因子达到了3.01,α为2.28,优于其它功能单体参与得到的聚合物识别特性;TFMAA-co-TRIM聚合物粒径介于300 nm至1.5μm之间,作为色谱固定相具有良好的通量和低的柱压;在乙腈流动相中,TFMAA-co-TRIM分子印迹固定相的分离过程主要被焓驱动,低温有利于分子印迹固定相分离甾醇结构类似物;TFMAA-co-TRIM分子印迹聚合物在255.84℃时开始熔融,Tp=257.40℃,聚合物CP的降解温度在267.79℃,MIP降解温度在343.11℃,制备的固相微萃取头初步经GC/MS 270℃的耐热性测定;不同的洗提溶剂筛选证明了选择接近聚合溶剂的洗脱体系更有利于MISPE发挥识别效应;分子印迹固相萃取柱对孕酮、17α-雌二醇、17β-雌二醇和雄烯二酮都具有不同程度的保留特性,可作为此类化合物的吸附材料,特别对孕酮强保留的富集特性,可作为孕酮的选择性识别吸附剂,其分子印迹聚合物对17β-雌二醇的吸附动力学测定显示在50 min内基本达到吸附平衡,具有作为传感器核心敏感材料的潜力;对比萃取奶粉中17β-雌二醇性能,MISPE柱比非分子印迹固相萃取柱和C18柱具有更高的保留,回收率依次为85.5%,43.7%和30.7%。

Abstract] objective to assess a new imaging technique,optical coherence tomography,for the diagnosis of central serous choroidoretinopathy.methods forty-five cases (45 eyes) of csc were examined by ophthalmoscopy,binocular indirect ophthalmoscopy and oct.some patients were monitored by oct.results in images of oct in 45 eyes of csc,42 eyes showed serous neurosensory detachement,2 eyes appeared retinal pigment epithelial detachement and 1 eyes combined neurosensory detachement with pigment epithelial detachement.monitoring images of oct in 9 eyes revealed absorption of serous fluid and decrease of neurosensory detachment.conclusion oct is potentially useful as a new and noninvasive diagnostic technique for quantitative examination of patients with csc and objectively monitoring the clinical course of the serous retinal detachement in this disease.

摘要] 目的评价光学相干断层成像(optical coherence tomography,oct )对中心性浆液性脉络膜视网膜病变的临床诊断价值。方法对45例(45眼)中心性浆液性脉络膜视网膜病变患者散瞳后分别进行直接检眼镜、双目间接检眼镜、oct 检查。9例复查时再次进行oct检查。结果 45眼中心性浆液性脉络膜视网膜病变的oct 图像,42眼表现为单纯神经上皮层脱离,2眼为单纯色素上皮层脱离,1眼同时存在神经上皮层脱离和色素上皮层脱离。9眼复查的oct通过测量脱离高度的降低可观察到液体的不同程度吸收。结论 oct 是一种新的、无损伤性的、非接触性的、并能定量的检查方法,能明确中心性浆液性脉络膜视网膜病变的脱离部位,并能进行定量的追踪观察。

The calculated results show: the ground state structures of PtNi5, Pt2Ni4 and Pt3Ni3 clusters are quadrangular bi-pyramid, and Pt4Ni2 and Pt5Ni clusters are triangular bi-pyramid with hat and triangular pyramid with quadrilateral, respectively. From the point of view of thermodynamics, PtnNim clusters are stable because of the negative enthalpy of formation; the positive NICS of PtNi5 clusters show anti-aromaticity, The negative NICS of Pt2Ni4 and Pt5Ni clusters show aromaticity. The number of the IR absorption peak of Pt3Ni3 is the most. The IR and raman absorption peak of PtNi5 , IR of Pt2Ni4, Raman of Pt3Ni3 and Pt4Ni2 have only one. The absorption peak of Pt5Ni appears in the bigger frequencies only, and is zero almost in the small frequencies.

研究结果表明:PtNi5、、Pt2Ni4、Pt3Ni3团簇的基态结构都为四角双锥结构,Pt4Ni2 和Pt5Ni团簇的基态结构分别是戴帽三角双锥和三角锥戴四边形结构;PtnNim团簇的生成焓都为负值,表明团簇在热力学上是稳定的;由NICS值可得,PtNi5团簇具有反芳香性,Pt2Ni4和Pt5Ni团簇具有芳香性;从光谱分析来看,Pt3Ni3团簇的IR较强吸收峰的个数最多,PtNi5团簇的IR和Raman、Pt2Ni4团簇的IR、Pt3Ni3和Pt4Ni2团簇的Raman只有一个强吸收峰值,Pt5Ni团簇的峰值只出现在频率较大的位置,频率小的位置几乎为零。

Based on the absorbance change of indicators with the concentration of hydrogen ion released from the enzyme-catalyzed reaction, a convenient colorimetry method is established for the assay of acidic phospholipase 〓 and glycogen phosphorylase b Brilliant yellow and bromothymol blue are chosen as indicators for assays of acidic phospholipase 〓 and glycogen phosphorylase b by following the absorbance changes at 495 nm and 615nm respectively The method is simple, sample-saving, sensitive and valid for a wide range of enzyme concentrations.

为了研究糖原磷酸化酶的激活动力学和酸性磷脂酶〓的复性过程,我们根据酶催化反应中释放氢离子浓度的变化引起相应的指示剂的光吸收发生变化的原理,建立了一种简捷的比色法,用于测定酸性磷脂酶〓和糖原磷酸化酶b的活性。选用亮黄和溴麝香草酚兰分别作为酸性磷脂酶〓和糖原磷酸化酶b测活的指示剂,在495 nm和615 nm处检测二者的光吸收值的变化,可以测定酶活。本方法的优点是,可在比较宽的酶浓度范围内进行活力测定,而且操作简单、节省样品、灵敏度高。

The reason is that warm has functions of stimulating tissue regeneration, alleviating pain and increasing tissue nutrition, when warm acts on surface wound, serous effusion increases, which helps to eliminate pathological products; warm can make blood vessel dilative and enhance vascular permeability, which is propitious to discharge tissue metabolites, absorb nutriment, restrain development of inflammation and advance the healing.

究其原因,是因为温热可刺激组织再生且有减轻疼痛和加强组织营养的作用,当温热作用于体表的创口时,浆液性渗出物增多,能协助消除病理产物;热可使血管扩张,血管通透性增强,有利于组织代谢产物的排出和对营养物质的吸收,抑制炎症的发展,促进其愈合。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周,炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节,另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg,20分钟后踝关节照光,激光波长627.sum,功率密度 100mwcm',照射时间1000秒,能量密度100)/。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径,治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后,治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗,随机治疗一侧膝关节,另一侧作自身对照。兔耳静脉注入I'arrainrelomg/Kg,20分钟后,膝关节用金蒸气激光照射,激光能量密度100)儿旷。24 /J'时后取膝关节滑膜作病理检查,并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果: 1。模型观察:CIA大鼠炎症高峰期滑膜下炎细胞浸润明显,滑膜细胞明显增殖,炎症达到高峰后二周,血管缀形成,并侵蚀和破坏软骨和骨, CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生,滑膜下炎细胞浸润,也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明,各组织对HMME 的吸收速度和吸收量不同,荧光值一时间曲线不同,滑膜组织比皮肤和软骨对 HMME的吸收多,在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明:PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性,但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好,统计学检验差异有显著性。。3_军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少,图像分析结果表明面密度(阳性染色的面积总和与统计视野面积的比值)治疗组小于对照组,统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多,图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组,统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小,与对照组相比,统计学检验差异有显著性。结论:二。CIA、AIA的病理改变类似人类RA,可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同,滑膜组织比皮。

In details, the strongest inhabitation to the shoot growth was observed when neutral soluble fractionates were supplied. The shoot biomass with neutral soluble fractionates added was decreased by 10.52% over the blank control, resulting in obvious increase of root: shoot ratio. It suggests that the root exudates would be self-poisonous. Besides, both acid and alkaline soluble fractionates exhibited the trend to increase the stem height and it is necessary to exploit the reasons.

在培养液中,分别加入分组的烤烟根系分泌物,均显著降低根系对NO_3~-、H_2PO_4~-、K~+离子的吸收和根系活力,推测根系分泌物中产生抑制作用的物质可作用在相当宽的pH范围;其中,碱溶性组分对H_2PO_4~-、酸溶性组分对K~+、中性组分对NO_3的吸收和根系活力的抑制作用较强,推测在烤烟根系分泌物中,可能存在多种抑制烤烟生K和养分吸收的化学物质;另外,抑制作用随着根系分泌物浓度的增加而增强。

We using the Si substrate has 200μm thickness SiO because of its low absorbing and scattering, so it could be the anti-reflection layer;it also has well-variable refractive index、well-transmittal and well-heated stability of JSR THB-120N negative photoresist which we choice to be materials to develop the polymer waveguides.

选择具有成长200μm厚度的二氧化矽之矽晶片作为实验所需之基板,因为二氧化矽对光具有低本质吸收及低散射性等特质,故可作为所设计之抗反射层;所使用的光阻为JSR THB-120N来作为制作高分子波导的材料,它具有可调折射率、良好的导光性以及良好的热稳定性等。

It can promote calcium deposition in teeth and bones, the maintenance of their normal growth; can promote intestinal absorption of iron to prevent iron deficiency anemia; to enhance the baby's body resistance, to avoid recurrent fever; can also enhance the capillary wall of the flexible and compact, bone and skin to prevent bleeding.

它能够促使钙质沉积在牙齿和骨骼上,维持它们的正常生长;可促使铁质在肠道吸收,防止发生缺铁性贫血;能够增强宝宝身体的抵抗力,避免经常感冒发烧;还可增强毛细血管壁的弹性和致密性,避免骨和皮肤出血。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。