可发现性

Ultrasonographic scans, fetal genetic studies, and hormonal assays of amniotic fluid can diagnosis certain diseases, fetal sex differentiation disorders, fetal endocrinal disorders, and chromosome abnormality.

产前超声发现胎儿生殖器官异常可作为筛查指标之一，联合羊水中激素检查可早期诊断某些胎儿生殖器官异常、胎儿性分化异常、胎儿内分泌代谢异常、胎儿染色体异常相关疾病。

TREATMENT: Except for anti-coagulation therapy, aminophyllini was an inexpensive medicine to treat PTE, it could largly lower Hb and Hct by reducing the secretion of EPO. Its defect was rechallenge of PTE with the drug stopped, and repeated administration was still effective. The side effect was exciting symptoms. Enalapril was a storng hypotensor which could also greatly lower Hb and Hct with the decline in PRA/AT-Ⅱ, and then decreasing serum EPO. In this therapy blood pressure shonld be monitored to prevent from postural hypotention. At last, it showed that diltiazemi had no obvious effect on PTE.

四、治疗研究：分别以氨茶碱、恬尔心、Enalapril来治疗PTE病人，发现氨茶碱能明显降低PTE病人的Hb及Hct，且该作用与EPO降低有关，其缺点是停用后可引起复发，但继续服用仍有效，该药的副作用主要为头痛、失眠等兴奋症状；Enalapril不但能显著降低Hb及Hct，还可治疗难治性高血压，适用于伴有高血压的PTE病人；恬尔心对PTE的治疗作用不大。

Besides neurokinins, recently we found that the dominant opioid receptor, delta subtype, was existed in renal pelvis and intrapelvic activation of DOR resulted dose-dependent increases in ANRA, suggested that DOR plays a role in regulating renal sensory response.

除了神经激肽受体之外，本实验室最近也发现类鸦片受体在肾盂表现并且其中以delta亚型的类鸦片受体（delta-opioid receptor， DOR）为主，活化肾盂内DOR可够剂量依存性地增加传入性肾神经的活性，所以DOR可调控肾脏感觉功能。

CaN Aβ gene silencing can reduce myocardial hypertrophy in cultured cells, si1280 (21bp) of CaN Aβ gene is the most effective target site for siRNA. The method of intrapericardial injection of plasmid, microbubbles and erzymes can improve transfection efficiency of non-viral plasmid with satisfying targeted transfection. But the scope of transfected myocytes is still limited. CaN Aβ shRNA expressing plasmid transfection in vivo by pericardial injection results in decreased CaN Aβ protein expression of small part of myocytes, and CaN Aβ mRNA only shows decreased trend. The dosage of non-viral vector and the parameters of ultrasound energy should be optimized in further study.

结论RNAi技术抑制CaN Aβ基因表达可有效减轻Ald诱导的心肌细胞肥大程度；CaN Aβ基因中si1280(21bp)片段为实现RNAi的更有效片段；微泡+酶类心包腔内注射超声导入的方法可有效改善非病毒载体在体心肌的转染效率，同时具有一定的靶向性，但总的转染范围仍然有限；采用这一方法进一步进行&一肾一夹&心肌肥大模型大鼠在体心肌细胞的CaNAβ的RNAi干预，发现心肌肥大大鼠心外膜下局部心肌细胞CaN Aβ蛋白水平降低，CaN AβmRNA水平虽有下降趋势，但无统计学差异，提示质粒的用量及超声导入的参数有待进一步研究使其优化。

This study demonstrates the integral function of SA, particularly streptococcal DNA, in the pathogenesis of psoriasis.

该研究通过揭示链球菌抗原的生物学功能，发现non-NASA相比SA可显著降低银屑病患者PBMC增殖和T细胞活化，提示链球菌DNA可辅助活化致病性T细胞，诱导银屑病的发生与发展。

Meanwhile, our successive observations for 3 generations on several lines of untransformed regenerants indicated that, their fertility under long-day showed a trend to return to normal level of original materials with the advancement of generations. But the transgenic lines still kept more stable and relative higher level over the control under long-day.

然而，通过对部分株系连续三代的初步观察，发现组培再生植株随世代推移长日条件下育性表达水平有逐步回复原始材料水平趋势，而转基因株则可保持稳定的较高长日可育水平。

Firstly, there are less secure and efficient threshold schemes; secondly, the research on multi-secret sharing is rather weak; thirdly, usual verifiable secret sharing don't consider the partners' anonymity, while it is just people's expectation. Last but not least, the problem of variety on shares is becoming a more obvious restrict of efficiency, especially in the facets of the lost and being districted of shares. On the application of verifiable secret sharing, there are also two inadequates : on the one hand , verifiable secret sharing has been used in much threshold cryptography but in less verifiable signatures.

然而，经过认真总结、分析该领域目前研究的发展状况（具体结果将在第一章给出），我们发现在可验证秘密分享的研究方面，仍有下列四个不足之处：一是现有的安全、高效的门限方案不多；二是对多秘密分享的研究非常薄弱，在已有的文献中还见不到安全、实用的可验证多秘密分享方案；三是通常的秘密分享方案没有考虑秘密分享者的匿名性，而这恰恰是人们所希望的；四是秘密分享者的动态管理问题已经越来越明显的制约现有方案的安全，尤其是密钥份额丢失或被破坏时如何恢复更是没有被深入探讨。

The results show that DCRP is indeed a excellent flame retardant. The material can reach the UL-94-V-0 level through choice different synergist. Many alternative synergists to antimony oxide are available for use. Zine and iron compounds are often used in place of the standard antimony oxide because of their lower cost and special properties. Additionally, synergist mixtures are also useful in obtaining specific properties.

本文在参考国内外文献的基础上自行设计了一些配方，分别把得克隆应用于尼龙66、尼龙6、PBT、PP、ABS等材料中，对得克隆进行了应用研究实验，发现得克隆可赋予材料优异的阻燃性，通过选用不同的协效剂一般可以达到UL-94-V-0阻燃级别，并且，可供选择的协效剂不仅是三氧化二锑，还有多种其他化合物如氧化铁、硼酸锌等及它们的配合物，这类协效剂在某些方面还优于三氧化二锑。

The results show that DCRP is indeed a excellent flame retardant. The material can reach the UL-94-V-0 level through choice different synergist. Many alternative synergists to antimony oxide are available for use. Zine and iron compounds are often used in place of the standard antimony oxide because of their lower cost and special properties. Additionally, synergist mixtures are also useful in obtaining specific properties.

本文在参考国内外文献的基础上自行设计了一些配方，分别把得克隆应用于尼龙66、尼龙6、PBT、PP、ABS等材料中，对得克隆进行了应用研究实验，发现得克隆可赋予材料优异的阻燃性，通过选用不同的协效剂，一般可以达到UL-94-V-O阻燃级别，并且，可供选择的协效剂不仅有三氧化二锑，而且还有多种其他化合物如氧化铁、硼酸锌等及它们的配合物，这类协效剂在某些方面还优于三氧化二锑。

Another drug－ the once-popular allergy medication Seldane, which was removed from the market in 1997－ was found to cause life-threatening cardiac arrhythmias and in some cases resulted in death when taken with certain other drugs.

另一种药－－曾经常用的抗过敏药，Seldane，1997年撤市－－被发现可引起致命性的心律失常，且和某些药物联合使用时可致患者死亡。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。