可以抑制的

The results show that the decalescence of catalyst bed affects the process of hydrogen peroxide catalytic decomposition greatly. If the catalyst bed is preheated or made up of materials with low thermal conductivity, that influence can be depressed. At the same time, the response characteristic of catalyst bed and the efficiency of catalytic decomposition can be improved. The low frequency pressure instability of catalyst bed occurs because of the coupling of catalytic decomposition and supplying. The decomposition plane pushes all the way through the catalyst bed during pressure oscillations, causing unreacted liquid hydrogen peroxide to be exhausted from the bed and leading to the appearance of liquid hydrogen peroxide channeling. Consequently, how to prevent or at least limit this channeling is the key to eliminate the pressure instability of catalyst bed. It was found that adding clapboard to the catalyst bed can depress the pressure instability efficiently.

结果表明催化剂床及催化剂的吸热对过氧化氢分解过程影响很大，对催化剂床进行预热或采用热导率低的材料制造催化剂床等措施，可以降低催化剂床壁面吸热对催化分解过程的影响，提高催化剂床的响应特性和催化分解效率；催化剂床的低频不稳定是催化分解过程与供应系统耦合产生的，催化剂床气体界面的波动过程中，液体过氧化氢穿透催化剂床形成过氧化氢液体通道，过氧化氢液体通道的产生和扩大是催化剂床不稳定的主要原因，也是消除催化剂床不稳定的关键，试验中在催化剂床内加入分流板成功地抑制了催化剂床的低频不稳定。

The results indicate seawater concentration has no effect on absorbency, pH, relative density, dry matter and water contents in Aloe vera leaves. While, seawater stress causes increased MDA and membrane penetration, decreased phytochroms, prolines and NO_3~--N. It is beneficial to plant growth when irrigation was done with 10% seawater, because of higher ratio of K~+/Na~+ and lower ratio of Na~+/Ca~(2+). In addition, the polysaccharide contents in Aloe vera leaves increase twice and triplication under 25% and 50% seawater irrigation respectively, the barbaloin contents increase over triplication in var. 75% seawater and over twice in var. 50% seawater and var. 100% seawater. However, when seawater concentration exceeds 25% the growth of plant was inhibited, biomass decreased, flowering time was deferred, Ca~(2+) content decreased caused by Na~+ accumulation in leaves.

结果表明：在海水胁迫下，库拉索芦荟全叶汁的吸光度、酸度、相对密度、总固形物和水分含量总体上受海水浓度的影响不大；但芦荟叶的丙二醛含量和质膜透性增加，叶绿体色素、脯氨酸和硝态氮含量减少；在10％海水浇灌下，芦荟叶细胞具有较高的K~+／Na~+比和较低的Na~+／Ca~(2+)比，对库拉索芦荟的生长有一定的促进作用；在25％海水和50％海水浇灌下，芦荟多糖含量提高了2-3倍；在75％海水浇灌下芦荟甙含量增加了3倍多，在50％海水和100％海水灌溉下，其含量也增加了2倍多；当海水浇灌浓度超过25％后，库拉索芦荟的生长明显受到抑制，生物量降低，抽苔期推迟，同时，海水浓度的增加也导致芦荟叶中累积大量Na~+，从而使得芦荟叶中Ca~(2+)含量降低，但Mg~(2+)并没有受到海水浓度的影响；用浓度低于75％的海水浇灌库拉索芦荟可以降低剖面深度在0-100cm之间的土壤盐度；其抗氧化保护酶中超氧化歧化酶的酶活力相对保持稳定，过氧化物酶的酶活力在10％海水浇灌下明显提高，随后则下降，而过氧化氢酶的酶活力则随海水浓度的升高而下降。

In this paper, we studied M. meretrix ferritin, cathepsin B and caspase genes, which are involved in clam larval shell formation, nutrition, metabolism and apoptosis, respectively. We have cloned the three genes, investigated the temporal and spatial expression profile both at gene and protein level in trochophore (L1), D-veliger (L2), pediveliger (L3) and postlarvae (L4). The potential roles of these proteins were analyzed with specific inhibitors during larval development. Firstly, embryos were found developed into trochophore-like larvae with no shell if cultured at gastrula stage in artificial seawater without iron. Shell-like structures were formed only in the presence of iron. The larvae which had been transferred at L1 stage into ASW developed normal shell. This indicated that iron and iron associated protein are important for larval shell formation. The EST sequence which is homologous with ferritin, which is a principal iron metabolic protein, was selected from the M. meretrix cDNA library. The full-length of ferritin subunit cDNA was cloned by RACE. The results of real-time PCR revealed that the MmeFer mRNA expression changed before and after the larval shell formation.

本论文以文蛤幼虫为研究对象，分别对文蛤幼虫发育过程中贝壳形成相关的铁蛋白、营养及变态相关的组织蛋白酶B及变态过程中细胞凋亡相关的caspase三个基因进行了克隆，分析了基因及编码蛋白在担轮幼虫期(L1)、D形幼虫期(L2)、壳顶幼虫期(L3)和稚贝期(L4)的时空表达特征，解析了其可能的功能，并研究了相应酶类的特异性抑制剂作用对幼虫发育过程的影响，进行了目标蛋白的功能验证，详述如下：研究结果显示，在文蛤胚胎发育到原肠胚时放入不含铁离子的人工海水中培养，发育成无壳的畸形，随着人工海水中铁离子添加浓度的升高，幼虫长出壳状组织接近正常状态；而发育到L1期幼虫放入不含铁离子的人工海水中培养却可以发育出正常的壳，推测铁和铁代谢相关蛋白在幼虫贝壳初始形成有重要的作用。

At the one-cell stage, each embryo was injected with gradient doses of 2-8ng MO. The control morpholino, was purchased from Gene-Tools.To test the knockdown effectiveness of the morpholino, the tbx2-EGFP (enhanced green fluorescent protein) construct was generated. And coinjection of morpholino with mRNA tests its specificity of the morpholino. Overexpression of tbx2 via mRNA microinjection helps us understand gaining function of tbx2. Results The tbx2-EGFP construct tests the knockdown effectiveness of the morpholino. Zebrafish embryos lacking tbx2 function have defects in cardiac contractility, rhythm and morphology in a dose-dependent manner. The embryos with c-MO are normal in development. Coinjection of morpholino with mRNA rescue the phenotype of tbx2 knocking down. The phenotypes include pericardial edema, hypogenetic ventricle, dilation of atria, arrhythmia, bradycardia, asystole, abnormal atrioventricular canal, aberrant valve and blood regurgitation.

结果荧光蛋白融合标记实验验证了tbx2-MO可以很好得阻抑斑马鱼胚胎tbx2的表达，tbx2-MO组胚胎在心脏收缩性、节律和形态学发生上出现了异常，心脏畸形随着注射剂量的增加而出现比较一致的表型，而c-MO组胚胎没有出现明显的畸形；tbx2-mRNA和tbx2-MO的共注射减少了tbx2-MO胚胎心脏畸形的发生率及减轻了心脏畸形的程度，验证了所设计合成的tbx2-MO对tbx2基因的抑制作用具有特异性；tbx2-MO组胚胎心脏缺陷包括心室发育不良、心房扩张、房室管和瓣膜异常以及心率缓慢、心律不齐、心脏停搏、血液返流等，并根据心脏发育异常的程度分为轻、中、重度畸形组tbx2-mRNA基因过表达胚胎没有见到心腔的形成。

The resulting strain, designated YES2MTM1, was transformed with a yeast genomic library. Transformants lost the plasmid overexpressing MTM1 after 5-FOA treatment. Yeast strains able to grow on nonfermentable carbon source with MTM1 deletion and overexpression of some DNA fragments were picked up and candidate suppressor genes were identified. Overexpression of five genes were identified to be able to rescue the growth defect on nonfermentable carbon source. The study will provide reference for MTM1 gene function and screening for suppressor of genes whose deletion result in irreversible damage.

为了避免MTM1缺失造成的不可逆损伤，在野生型酵母中先转入带有MTM1 基因的质粒，再敲除染色体上的MTM1 基因，随后转入基因组文库，再利用药物5-氟乳清酸(5-FOA)迫使细胞丢失表达MTM1基因的外源质粒，再筛选能在非发酵培养基上生长的转化子，通过这种方法筛选发现，POR2等5个基因的过表达可以挽救MTM1 基因缺失造成的非发酵培养基上的生长缺陷，为深入了解MTM1基因的功能提供了线索，对筛选其他造成不可逆损伤的突变基因的抑制基因提供了一条可行的研究思路。

These results indiacated that tranferring macrophages combinedwith cytokines could be a new adoptive immunotherapy protocol foradvanced cancer,and rTNF used in vivo locally could induce andactivate macrophages to kill tumor cells.Monocytes when activatedunderwent a series of phenotypic and functional changes includingthe expression of IL-2R which may provide an important immunoregu-latory pathway.The presence of lectin-like molecules on thesurface of monocytes and tumor cells may bring theeffector/target cells together,thus facilitating the inductionof apoptosis in target cells by triggering the production ofcytolytic factors and the modification of target of targer cell surface anti-gens.(such as HLA-DR).

综合以上结果可以得出以下结论：转输巨噬细胞并结合细胞因子的联合应用是肿瘤继承性免疫中的又一新的、有潜力的方法；抗肿瘤细胞因子rTNF可通过激活巨噬细胞在体内抑制对其不敏感的肿瘤细胞的生长；人单核细胞在一定条件下激活后，可表达IL-2R，进而一方面增强其自身对IL-2的敏感性，另一方面在体内也具有调节T细胞功能的作用；单核细胞和肿瘤细胞上存在的凝集素类受体可促使两种细胞之间在凝集素介导下相互接近，并诱发单核细胞产生细胞毒因子，以及通过调节靶细胞上表面抗原的表达，促进诱导靶细胞的细胞凋亡。

Which can be used as the body of vitamin B1 coenzyme of many enzymes in the normal human body has an important role in glucose metabolism, it can inhibit the activity of cholinesterase, and choline esterase is an important neurotransmitter, and thus nerve conduction impact; vitamin B2 in the organization by participating in a variety of yellow enzymes constitute a coenzyme, its role in bio-oxidation process in the delivery of hydrogen role in regulating the body's metabolism process; vitamin B6 can also be a variety of enzymes as coenzyme participate in all kinds of amino acid metabolism, promote the absorption of amino acids and protein synthesis, cell growth is necessary for the material, which also promote fat metabolism, involved in neurotransmitter synthesis, hemoglobin synthesis and the impact on the normal reproductive functions such as human body an important metabolic process, Volkswagen Medicine Net: What liver protection effect of vitamin B family?

可作为维生素乙许多酶的辅酶，在正常人体组织中有一个用糖代谢的重要作用，能抑制胆碱酯酶活性，和胆碱脂酶是一个重要的神经递质，神经传导，从而影响；由黄色参与各种酶在组织中维生素B2构成辅酶，其作用在生物氧化氢的作用，调节人体的代谢过程中产程；维生素B6也可以是作为辅酶参与氨基酸代谢的各种酶的品种，促进氨基酸的吸收和蛋白质合成，细胞生长是必要的材料，这也促进脂肪代谢的神经递质合成，血红蛋白合成和参与，如影响人体生殖功能的正常新陈代谢过程中一个重要的，（大众医药网：什么样的维生素B家庭肝脏的保护作用？

These results, together with the structural elucidation of the purified polysaccharides described above, indicate that the α-glucans in G. lucidum don't have any remarkable immunomdulating activities, but the effects of β-glucans on immune system depend on their glycosyl residue linkages and sugar chain conformation. Further, it is concluded that the 1, 3-linked backbone, relative lower side chain size and substitution, and a high-organized helical structure are the beneficial structural features for the immunostimulatory activity of β-D-glucans. However, the 1, 6-linked backbone may induce the immunosuppressive effect of β-D-glucans.

结合各纯化多糖的结构与构象分析的结果，可以得出以下结论：赤灵芝中的α-型葡取糖不具有显著的免疫调节作用，而β-型葡聚糖的免疫作用则与其糖链结构和糖链构象有密切关系，1，3-连接的主链，较低的分支取代率和较短的支链长度及高度有序的螺旋结构是β-型葡聚糖发挥免疫增强功能的有利结构因素，相反，1，6-连接的主链却可能引起多糖的免疫抑制作用。

To solve the exsisting problems in the realization of the LFM/CW radar, the thesis presents a technique for dynamically measuring the LFM/CW signals, which can accomplish the dynamic measurements of FM linearity, FM bandwidth and FM slop of the transmitted signals of LFM/CW radars. This technique creates an effective and accurate means of judging the performance of LFMCW radars. The linearity-correction techniques presented in the thesis successfully make the linearity of the transmitted signals of an actual LFM/CW radar reduce from approximately 25% to 0. 1%(or r. m. s linearity of 0.04%), better than the best results (0.22%) obtained by foreign researchers with complex linearization closed-loop in the same kind of LFM/CW radars, according to the published literatures during the last decade. In order to improve the capability of the real-time processing and range-cells management of LFM/CW radars, the principle of equivalent mixing by lacking-sampling process of band-pass real signals is proposed based on the well-proved improvedversion of sampling theorem of band-pass real signals. This principle is used to configure the range-segments processing of the beat signals of an actual LFM/CW radar. The techniques of system-background interference suppression and the beat signal's dynamic range suppression are proposed, and are realized in an actual LFM/CW radar to demonstrate their effectiveness.

针对线性调频连续波雷达实现中急待解决的技术问题，文中提出并验证了线性调频连续波信号的综合动态测试技术，可以完成对线性调频连续波雷达发射信号的扫频线性度、扫频带宽和扫频斜率的综合动态测试，为衡量实际线性调频连续波雷达的系统性能创立了精确有效的测试手段；文中建立的非实时闭环动态校正技术使一部实际的线性调频连续波雷达的发射信号（时带积3×10〓）的扫频线性度从25%改善为0.1%（方均根线性度0.04%），优于国外已公布的80年代同类雷达中采用复杂的实时闭环动态校正环路所获得的实际结果（0.22%）；为了改善线性调频连续波雷达的实时性和分辨单元数处理能力，文中发展完善了实带通信号的采样定理并给予了严格证明，并在此基础上提出了欠采样等效混频原理，将其应用于实际线性调频连续波雷达的距离分段处理中；针对线性调频连续波雷达中系统背景干扰和回波动态范围问题，创立了系统背景综合抑制技术和频域动态范围压缩技术，并将它应用于实孔线性调频连续波雷达系统中，显示出它们的有效性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。