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Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前,Mahon医师等人主导一个先驱研究,探索完整分子生物学上缓解之CML病患停用imatinib的可能性,在总共15名病患中,7人在6个月内復发,但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解,其他8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前,Mahon医师等人主导一个先驱研究,探索完整分子生物学上缓解之CML病患停用imatinib的可能性,在总共15名病患中,7人在6个月内复发,但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解,其他8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前,Mahon医师等人主导一个先驱研究,探索完整分子生物学上缓解之CML病患停用imatinib的可能性,在总共15名病患中,7人在6个月内复发,但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解,其它8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

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