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VLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

ConclusionsVLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

结论VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

Using true metabolizable energy method to evaluate the available nutritive value of acorn kernel, while maize and rice were used as control.

以京白种鸡作试验动物,以玉米、稻谷作对照,采用鸡真代谢能法研究野生经济植物资源橡籽仁的可利用营养价值。

A small amount of use, digestible energy of wheat close to corn, the chicken metabolizable energy lower than corn; a large number of use, due to the role of non-starch polysaccharide anti-nutritional effects, available energy lower than corn.

少量使用时,小麦消化能和玉米接近,鸡代谢能低于玉米;大量使用时,由于受非淀粉多糖抗营养作用的影响,可利用能量低于玉米。

DATA EXTRACTION: MRS defines the dynamic changes of cerebral metabolic substance following traumatic brain injury, and such changes in the white matter suggest the degree of neuraxon injury, while those in the gray matter indicate the state of brain laceration.

资料提炼:磁共振波谱分析可反映创伤性脑损伤后活体脑组织代谢物质的动态变化。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速,应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等,其中自杀基因被认为是最有前景的基因治疗方法,它又称病毒介导的酶/药物前体疗法,是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中,该基因表达的产物可将无毒的药物前体转化为毒性药物,从而选择性杀伤该肿瘤细胞,常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因,前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物,然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷,作为DNA合成链的终止剂和DNA合成酶的抑制剂,干扰细胞DNA的合成;后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶(5-FC)脱氨成为5-氟尿嘧啶(5-FU),然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸(5-FUTP)和5-氟-2′脱氧尿嘧啶-5′磷酸(5-FdUTP),5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成,5-FdUTP则作用于胸苷合成酶,导致TMP衰竭而阻止DNA的合成,最终诱导肿瘤细胞凋亡。

Key words: aerobic exercise; non-alcoholic fatty liver; serum lipid metabolism; liver histolomorph; oenothera erythrosepala borb

月见草结合有氧运动可有效调节非酒精性脂肪肝患者的血脂代谢病改善其肝脏形态。

D. polymorpha Some previous studies have reported that mussel tolerance to pollutants is regulated by seasonal changes (Van Benschoten et al., 1995) and by temperature (Harrington et al., 1997; Buschini et al., 2003a), since temperature-dependent metabolic and filtration rates (Quigley et al., 1993; Kilgour and Baker, 1994) can modulate exposure to toxicants.

四多形 先前的一些研究报告说,淡菜耐受污染物是调节季节性变化(范benschoten等基地, 1995年)和温度(哈林顿等人, 1997年;布斯基尼等人, 2003年),因为温度依赖性代谢和过滤费率(奎格利等人, 1993年; kilgour和贝克, 1994年),可抑扬接触毒物。

They were pipeline-like or reticulately arranged and could grow,differentiate and regenerate into new fat bodies in vitro culture,fina...

研究结果可为进一步探讨家蚕脂肪体细胞的分化及脂类代谢调节机制提供实验条件。

The two white-skin animals are suit for research of zoopery of increased-pigment disease, while the other two are suit for research of zoopery of reduced-pigment disease; and α-MSH is one of the most important indicators in the research of zoopery with pigment disease.

结论]白色昆明小鼠及白色FMN豚鼠适宜做色素增加动物实验研究,C57BL/6J小黑鼠及棕黄色HARTLY豚鼠适宜做色素减退动物实验研究;α-MSH可做为观测色素代谢障碍性疾病动物实验研究的一个重要指标。

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推荐网络例句

I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意,使我记忆犹新,那天你随着我的亲友从家里送我上轮船,搬运工迟迟不来,你毅然替我提着皮箱上船。

St. Nicholas became the patron saint of Russia, where he was famous for his red cape, flowing white beard, and bishop's mitre.

圣尼古拉成了俄罗斯人的守护神,在那里,他以身披红斗篷,留着飘逸的白胡须,戴着主教法冠而闻名。

Long periods of seeming invincibility. Though some industries or lines of business exhibit characteristics that endow leaders with virtually insurmountable advantages, and that tend to establish Survival of the Fattest as almost a natural law, most do not. Thus, for every Inevitable, there are dozens of Impostors, companies now riding high but vulnerable to competitive attacks. Considering what it takes to be an Inevitable, Charlie and I recognize that we will never be able to come up with a Nifty Fifty or even a Twinkling Twenty. To the Inevitables in our portfolio, therefore, we add a few "Highly Probables."

在所属的产业都被赋予其无可取代的优势地位,大者恒存的自然定律似乎牢不可破,但实际结果却不然,也因此在找到真正的真命天子之前,旁边可能还有好几打假冒者,这些公司虽然曾经红极一时,但却完全经不起竞争的考验,换个角度来看,既然能够被称为永恒的持股,查理跟我早就有心理准备,其数量绝对不可能超过五十家或甚至是不到二十家,所以就我们的投资组合来说,除了几家真正够格的公司之外,还有另外几家则是属于极有可能的潜在候选人。