只有当

The dose-dependent experiment revealed that Id1 antagonised E47 and Ets1 mediated transcriptional activation in a dose-dependent manner. With pGL3-870 as a template, site-directed mutagenesis of E-box and / or ETS-binding site was introduced into p16 promoter. E47 could not activate the transcription of p16 promoter with E-boxes mutated, and Ets1 could not activate the transcription of p16 promoter with EBS mutated. The synergy effect between E47 and Ets1 would occur only if the E-boxes and EBS were present. These facts demonstrated that E47 and Ets1 proteins were not recruited to the promoter by binding to other cis-elements or through interaction with other protein factors, however, they bound to DNA directly through respective consensus sequences in p16 promoter.

以pGL3-870为模板，构建了E-box或/和EBS点突变的p16启动子报告基因载体，将野生型和突变型的报告载体分别与pI-E47、pI-Etsl以及pI-E47+pI-Ets1共转染，发现E47和Ets1所诱导的转录激活作用依赖于启动子DNA上存在的各自的特异结合序列，二者的协同作用也只有当两个结合位点都存在时才会发生，说明E47和Ets1不是与其它作用元件或其它蛋白质因子相作用而被招募到该启动子的，它们是通过启动子上各自的特异结合位点与DNA直接结合的。

But what makes me "tap-dance to work " is when we show people something new

但只有当我们向人们展示某些成果的时候，我才会&跳着踢踏舞去工作&。

This app is not resident, so, it consumes memory only when you are configuring rotation support.

这个程序是常驻，因此，它占用的内存只有当你正在配置旋转才使用。

Objectivity can only be achieved, therefore, when all social constructions have been deconstructed.

因此，只有当所有的社会建构都被解构之后才能获致客观性。

A seed of corn must have 14%... in it to pop.

只有当一粒玉米种子里含有14%的水分时才能爆开。

A seed of corn must have 14% water in it to pop.

只有当一粒玉米种子里含有14%的水分时才能爆开。

When you heat a seed of corn, the water inside makes the corn explode.

只有当一粒玉米种子里含有14%的水分时才能爆开。

It's only when you realise that the bully has a different mindset from yourself and that he or she has the behaviour profile of the serial bully that this person's aggressive, disorganised, disordered behaviour starts to make sense.

只有当你意识到欺负者和你的想法不一样，他或她具有一位连环欺负者行为特征后，此人的侵犯性、瓦解和无章的行为才开始让人可以解释。

The results show that the effect of Li is to increase the rate of hardening, however, the addition of lithium does not progressively change age hardening and precipitation process of Al--Cu--Mg--Ag alloys with low Cu/Mg ratio, and significant age hardening response only occurs with the addition of 2.0\%Li.

结果表明，在Al--4.0Mg--1.5Cu--0.4Ag合金中添加锂，可以加速合金的时效进程，但其时效硬化效果并不能简单地随着含锂量的增加而逐步加强，只有当锂含量达到2.0\%时，才表现出显著的时效硬化与强化效果。

Only when they keep a peaceful heart can they face both favors and humiliations with composure.

只有当他们保持一个和平的心，他们既面临有利和屈辱与镇定。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。