口腔的

Objective: By observing and analyzing the different expressions of E-cad MMP-9 or CD44V6 at normal oral mucous oral atypical hyperplasia and oral squamous cell carcinoma, to investigate the relationship of their abnormal expressions cancerate and metastasis.

目的：通过观察E-Cadherin、MMP-9和CD_(44)V_6在正常口腔粘膜、口腔粘膜不典型增生和口腔粘膜鳞癌的不同表达，分析它们在口腔粘膜鳞癌及其癌变过程中的表达规律，探讨它们的异常表达与口腔粘膜癌变、转移的关系。

Objective By observing and analyzing the different expressions of MMP-9 at normal oral mucous, oral atypical hyperplasia and oral squamous cell carcinoma, to investigate the relationship of its abnormal expressions, cancerate and metastasis.

目的 通过观察MMP-9在正常口腔粘膜、口腔粘膜不典型增生和口腔粘膜鳞癌的不同表达，分析它在口腔粘膜鳞癌及其癌变过程中的表达规律，探讨其异常表达与口腔粘膜癌变、转移的关系。

Objectives To present the relationship between oral microecological imbalance and oral diseases, and the mechanism of oral malodor caused by oral diseases.

目的 介绍口腔微生态失调与口腔疾病的关系，口腔疾病出现口腔气味异常的机制。

To analyze comprehensively the significance and trend of studies on oral microecology and health, explore the regulatory effect of oral microecology on oral diseases, especially in eliniminating oral malodor.

综合分析口腔微生态与口腔健康的研究动态及意义。展望口腔微生态调整在口腔疾病治疗中的作用研究，尤其在消除口腔异味的积极作用。

Results: In contrast to negative expression in normal oral mucosa, survivin was expressed in 42 of 50 (84%) cases of oral squamous cell carcinoma samples. There was no significant correlation between survivin expression and age and sex. In squamous cell carcinoma tissues, the expression of Survivin gene stepped up following malignant degree, but the positive rate of Survivin was not statistically significant.

结果：Survivin蛋白在10例正常口腔粘膜组织中呈阴性，而在50例口腔鳞癌组织中有42例阳性，占84%，差异有极显著性(P.01)；COX-2蛋白在10例正常口腔粘膜组织中呈阴性，但在口腔鳞癌组织中的阳性率为86%(43/50)，差异有极显著性(P.01)；Survivin蛋白阳性率与年龄和性别无相关性，而与COX-2蛋白表达阳性呈正相关(P.05)。

Methods: 9 cases of exogenic OVC、6 cases of cystoid and infiltrative OVC、15 cases of well-differentiation OSCC and 15 cases of poor-differentiation OSCC were selected; two specimens, which were carcinoma tissues and the sur...

方法取9例外生型口腔疣状癌、6例囊肿／浸润型口腔疣状癌、15例高分化鳞癌、15例低分化鳞癌，应用半定量逆转录多聚酶链式反应方法检测口腔疣状癌和口腔鳞癌中OPN mRNA的表达水平，应用免疫组织化学法检测上述标本中OPN的表达及分布，判断差异。

Objective To analyze the CT and MRI manifestations of oral carcinoma,and to evaluate the value of imaging technologies in the diagnosis of oral carcinoma,thus to explore the most reasonable imaging method Methods 46 cases with oral carcinoma,proved by surgery and pathology （2 lip tumors,8 carcinomas of the gingival ridge,5 carcinomas of the buccal mucosa,24 tongue carcinomas,5 carcinomas of the floor of the mouth,2 tumors of the hard palate）,were analysed retrospectively32 cases were examined with CT and 14 cases with MRIImaging presentations were compared with surgery and pathology Results Of the 46 cases with oral carcinoma,22 were ulcerative lesion of infiltrative growth,24 were masslike lesion of extruded trowthOf the 32 cases examined with CT scan,27 were detected,5 were missed,the 4 missed cases were confirmed to be superficial ulcers by surgery and pathologyOf the 10 cases with bone destruction examined with CT scan,8 were manifested,2 were missedAnd of the 14 cases with MRI scan,all 14 were detected Conclusion CT and MRI scan are valuable for diagnosis of oral carcinomasThey can manifest the morphology and size of primary tumor,contiguous structures,bone invasion and cervical lymph node metastasisMRI is the optimal imaging method for superficial ulcerative lesion of infiltratibe growth

徐 锋，罗德红，唐威，欧阳汉，周纯武目的分析口腔癌的CT及MRI表现，评价影像检查在口腔癌诊断中的应用价值，探索合理的影像学检查方法。方法回顾性分析经手术及病理证实的口腔癌46例（唇癌2例，牙龈癌8例，颊黏膜癌5例，舌癌24例，口底癌5例，硬腭癌2例），其中32例行CT扫描，14例行MRI扫描，将影像表现与手术所见及病理结果进行对照分析。结果 46例口腔癌中，呈浸润性生长的溃疡型病变22例，外生性生长的肿物型病变24例。CT扫描32例，明确显示病变27例，遗漏病变5例，其中4例为表浅溃疡型病变。CT扫描病例中，10例有骨质侵犯，CT扫描准确评价8例，遗漏2例。MRI扫描14例，均准确评价肿瘤及其与周围结构的关系。结论 CT、MRI对口腔癌原发肿瘤的形态、大小、周围结构侵犯、颈部淋巴结转移的评价有重要价值。对于较小及呈浸润性生长的表浅溃疡型肿瘤，CT扫描尤其是CT平扫难以准确显示，应首选MRI。

Objective: To study the expression of osteopontin in oral verrucous carcinoma and oral squamous cell carcinoma, so as to investigate the role of this gene in the development of OVC and OSCC, and to validate the results of gene chip.

目的研究骨桥蛋白(osteopontin，OPN)在口腔疣状癌和口腔鳞癌中的表达，探讨其在口腔疣状癌和口腔鳞癌发生发展中的作用，对基因芯片结果进行验证。

When stratified by type of leukoplakia , the response was more pronounced in homogeneous lesions: complete regression was seen in 16 of 28 (57%) subjects with homogeneous leukoplakia , 2 of 8 with erythroplakia , 2 of 4 with verrucous leukoplakia , and 0 of 4 with ulcerated and nodular lesions.

以口腔黏膜白斑病的种类分层时，同类口腔黏膜白斑病的反应更加显著：28位同类口腔黏膜白斑病患者中，有16位(57%)得到完全的逆转；8位口腔黏膜红斑病患者中，有2位得到完全的逆转；4位口腔疣性黏膜白斑病患者中，有2位得到完全的逆转；8位溃疡性和结状损害患者中，没有任何人得到完全的逆转。

Light condition should pay attention to oral hygiene, local or chlortetracycline coated Bingpeng San glycerine; if red, powerful, and even oral mucosa have ulcers, good oral care should be more clean in the mouth, and timely infection control.

光照条件下应注意口腔卫生，地方或冰硼涂金霉素甘油三；若红，强大的，甚至口腔黏膜有溃疡，良好的口腔护理应更清洁口腔，并及时控制感染。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。