变构

Based on a series of shear creep tests of discontinuous plane with regular dentation,the relationship between shear creep and different normal stress,shear stress,and slope ratio is obtained.

文章在规则齿形结构面剪切蠕变试验的基础上，分析了剪切蠕变随不同的爬坡角、正应力和剪应力的影响，拟合了剪切蠕变曲线，并将拟合的方程与Burgers模型的本构方程进行了比较分析，讨论了Burgers模型中剪切模量、粘滞系数的变化规律及其影响因素，取得了较为理想的结论，为结构面剪切蠕变本构方程的建立提出了较为合理简便的方法。

Allosteric control enables the cell to regulate needed substances rapidly.

变构调控使细胞能迅速地调节所需物质的合成。

This paper discusses research progress in acetylcholinesterase molecular shape and three-dimensional structure, gene structure, and the relationship between allosteric acetylcholinesterase and pesticide resistance, as well as utilization of the molecular domain of acetylcholinesterase.

文章介绍了乙酰胆碱酯酶的分子形式、三维结构、基因结构，变构乙酰胆碱酯酶与抗药性的关系以及乙酰胆碱酯酶分子领域应用等方面的研究进展，并对乙酰胆碱酯酶的进一步研究提出了展望。

The simultaneous allosteric modulation of ligandgated ion channels by general anesthetics is entirely additive.

同时发生的全麻药对配体门控离子通道的变构调制作用完全是相加性的。

Standard patch-clamp technique was used to study the allosteric modulation of ATP sensitive by intracellular pH.

方法用人胚肾细胞表达Kit6.2野生型、R371H和P266T位点突变后的通道，用膜片钳技术研究突变后胞内pH对ATP敏感性变构调节的变化。

Allosteric enzymes are often multi-subunit proteins,with an active site on each subunit.

变构酶通常是多亚基蛋白质，每个亚基具有一个活行部位。

The modulation effect of Zn2+ on IATP belongs to allosteric modulation and may be achieved by changing the affinity of ligand-receptor.

结论Zn2+对ATP-激活电流调制效应可能是通过改变配体和受体的亲和力而实现的变构调制。

The Center for Advanced Biomolecular Research is primarily dedicated to education and research in biomolecular including mechanism and regulation of enzymes, Protein folding and stability, proteomics, enzyme regulation and design, mechanisms of enzyme allostery, nuclear magnetic resonance, structural biology, proteins and RNA folding thermodynamics.

高级生物分子研究中心主要致力于生物分子的教学与研究，其研究领域包括酶作用机理，蛋白折叠和稳定性，蛋白组学，酶调控和设计，酶变构机制，核磁共振，结构生物学，蛋白质和核糖核酸折叠热力学等。

Thirty SD rats were randomly divided into five groups: control, 1 week, 2 week, 3 week and 4 week and stimulating the right triceps surae was stimulated by electrical stimulator. Using real-time quantitative PCR measurement to measure two alternative splices of IGF-1(IGF-1Ea and MGF) and MyoG mRNA expressing of gastrocnemius and right biceps brachii.

SD大鼠30只，随机分为5组，每组6只，分别为对照组和1、2、3、4周电刺激组，刺激部位为右侧腓肠肌，实时荧光定量PCR法分别检测双下肢腓肠肌和前肢肱二头肌的胰岛素样生长因子-1(IGF-1)不同变构体肝型胰岛素样生长因子(IGF-1Ea)和机械力生长因子以及成肌分化因子(Myogenin， MyoG)mRNA表达。

The new rT joint not only has two rotation axes that intersect at right angle,but also has another rotational degree of freedom which can be used to modify the assembly of other joints.This can change the mobility of the parallel mechanisms that assembled with the new rT joints and leads to two types of metamorphic paralllel mechanisms:In the first type,the mechanism changes its topology by turning the new rT joints in all limbs into different configurations which reconfigures the constraints within the limbs or the assembly of all the limb constraints.This change of mobility is completed by two cases.One is illustrated by a 3PS and a 3C parallel mechanism,by altering the rT joint into different configurations there will produce or reduce local degrees of freedom and thus change the constraits to the moving platform.This qualifies the 3PS and 3C to have variable mobility from 3 through to 6 and from 1 through to 6 respectively.

该铰链除了一般Hooke铰的两个轴线互相垂直相交的旋转自由度外，还增加了一个可以调节该两个轴线之一的姿态的一个旋转自由度，通过此自由度调节该rT铰到不同的装配构型，可以改变用其装配的并联机构的自由度，由此产生两类新型的并联变胞机构：一类是机构的各个支链中都有rT铰，该铰链的不同构型可以改变各支链对运动平台的约束或整个支链组的组合形式而改变机构的自由度状态，3PS和3C属于前者，通过调节rT铰到不同构型可以使其支链产生或消失局部自由度，从而减少或增加支链对运动平台的约束，使得并联变胞机构3PS和3C分别具有自由度从3变到6和从1变到6的能力；3P属于改变支链组组合形式的机构，其rT铰的不同构型将改变整个支链组的几何约束组合，使得并联变胞机构3P可以有三转动、三平动或三平移(来源：ABCded9de论文网www.abclunwen.com)一转动的自由度形式。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！