变态性

To investigate whether the expression of cdc2 and cyclin B1 in spermatogenic cells during spermatogenesis is actually a temperature dependent event, in situ hybridization, Western blotting and immunohistochemistry analysis were used to study the expression of cdc2 and cyclin B1 in normal and cryptorchid testis. Results showed that heat would differentially hurt male germ cells in different developmental stages during spermatogenesis, especially the pachytene primary spermatocytes. Most of spermatogonia in contralateral cryptorchid testis were not harmed fatally by heat as yet, indicating that spermatogonia could resist to beat to a certain extent. In this case spermatogonia could develop to pachytene/diplotene primary spermatocytes, but they could not acquire the ability to complete the transition from mitosis to meiosis, and then appeared to go through apoptosis. Therefore, we could not find the descendants of meiosis: secondary spermatocytes and round spermatids, elongated spermatids and spermatozoon. The abdominal temperature had no significant influence on the transcription of cdc2 and cyclin B1 in the spermatogonia and pachytene/diplotene primary spermatocytes. In normal rabbit testis, cyclin B1 increased in the pachytene/diplotene primary spermatocytes before meiosis and reached its peak in the spermatids.

为了解精子正常发生过程中cdc2和cyclin B1表达的低温依赖性，我们利用原位杂交和免疫组化等方法，研究了正常和隐睾精子发生过程中cdc2和cyclin B1的转录和翻译调控活动，结果表明：（1）热对各阶段的雄性生殖细胞都有损害，粗线期的初级精母细胞尤为敏感，实验性隐睾内的精原细胞尚未完全受到"致命"影响，说明精原细胞对热有一定的耐受性，但即使成为粗线期／双线期初级精母细胞，却未能获得由有丝分裂过渡到减数分裂的能力，呈现不同程度的凋亡，所以在整个切片中找不到源自减数分裂的产物----次级精母细胞、圆形精子细胞，更谈不上长形精子细胞和精子的形成；（2）腹腔高温未明显地影响隐睾精原细胞和粗线期/双线期初级精母细胞中cyclinB1和cdc2的转录，说明高温并不是通过影响cyclin B1和cdc2的转录活动而导致生精过程阻断的；（3）正常兔睾丸组织中，〓在精原细胞和粗线期／双线期精母细胞中均有表达：cyclin B1蛋白在减数分裂前期的粗线期／双线期初级精母细胞中的表达量增加，于变态末期的精子细胞中达高峰。

Conspirators of Pleasure is Czechoslovakian famous movie director Jan Svankmajer s magnum opus, which described the abnormal pursuing of ordinary people in life by using surrealistic ploy.

《极乐同盟》是捷克著名导演史云梅耶的代表作品，以超现实主义的手法来描绘现实生活中普通人时性的一种变态的追求。

What is going on across this nation, in the form of sexual perversion, is no longer taking place in 'shady dens of iniquity somewhere on the outskirts of town', between men and women.

这是怎么在这个国家，在形式的性变态，不再是发生在'可疑窝点的不公正某处郊外的小镇'，男子和妇女之间。

They found no evidence of sexual deviance or pedophilia; they did not uncover any financial motive, either.

他们没发现他有变态的性取向或是恋童癖，也没找到他是受经济利益驱使的证据。

One of the most common sexual deviancy, Women and men had, in which men more, women less.

一种最为常见的性变态，男女皆有，其中男性较多，女性较少。

In a sex-obsessed age abstinence sounds unnatural and thus a cause of sexual deviancy.

在当今这个色迷欲痴的年代，禁欲听起来是反自然的，于是就变成了性变态的理由。

Come back and ask why I would be sexual deviancy followed, they said with a smile, there are a lot of Chinese girls doing prostitutes maybe ...

回来问及为什么我会被性变态跟随时，他们笑着说，那里有很多中国姑娘在做妓女，可能……妈妈保佑我。

Let me preface this ad by saying if you are a nut job, pervert or fruitcake, move on.

在看这个广告这前，你要弄清楚自己是否是个古怪的人，性变态者或是个疯子，继续

Mamet began writing at Goddard College in Vermont and attended the Neighborhood Playhouse School in New York; early off-Broadway successes like Sexual Perversity in Chicago brought notoriety in the mid- 1970s and led up to a Pulitzer Prize for 1984's Glengarry Glen Ross.

马默特开始写作戈达德学院佛蒙特州并出席了学校周边环境剧场在纽约举行；早期外百老汇的成功像性变态在芝加哥带来恶名在1970年代中期，并导致到1984年的普利策奖的 Glengarry峡谷罗斯。

At the end, I was of course arrested and your father became the hero of the hour: more indeed than the hero of the hour merely: your family now ranks, strangely enough, with the Immortals: for with that grotesqueness of effect that is as it were a Gothic element in history, and makes Clio the least serious of all the Muses, your father will always live among the kind pure-minded parents of Sunday school literature[13b], your place is with the Infant Samuel, and in the lowest mire of Malebolge[13.1] I sit between Gilles de Retz[13.2] and the Marquis de Sade

好像历史也带上了一点哥特式的离奇古怪，从而使历史和史诗之神克里奥成了众缪斯中最不正经的一位。靠着这份离奇古怪，结果是你父亲在主日学校的文学里将永远活在那些个心地和善纯良的父母之中 [1 3 b ] ，你将与少年塞缪尔并列，而在地狱最底层的污渎中，我将与崇拜撒旦的雷斯和性变态的萨德侯爵为伍 [1 3 c ] 。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。