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变态反应

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Methods OECs were cultured in the olfactory bulb of newborn wistar rat. OECs suspension was infused into the lateral cerebral ventriculus of AE rats, intraperitoneal methyl-vitamine B12 associated with above OECs suspension in combined transpiantion group, and the saline with the same quantity was infused in pseudo-operation group. Afterwards, sport-function grade, histo pathological change were observed.

用新生wistar大鼠嗅球培养OEC,移植组将OECs悬液注入实验性变态反应性脑脊髓炎大鼠的侧脑室;联合移植组在侧脑室注入OECs的基础上,腹腔注入甲基维生素B12;假手术组按以上方法注入等量生理盐水;观察两组大鼠运动功能评分、组织病理学变化。

ConclusionShuangxin Nasal Spray can significantly improve the allergia rhinitis,and it has many advantages,such as convenience, safety and low side effects and so on.

结论复方双辛喷雾剂对实验性变态反应性鼻炎有显著的改善作用,且具有方便、安全、副作用小等优点。

ResultsShuangxin Nasal Spray could obviously improve each kind of allergic rhinitis symptoms of guinea pig allergia models. Compared in medication administration groups with the control group,the nasal secretions,the frequency of sneezing and the times of griping nose are obviously reduced.

结果复方双辛喷雾剂对实验性变态反应性鼻炎豚鼠模型的各种变应性鼻炎的症状和体征均有明显改善作用;与模型对照组比较,各给药组动物鼻腔分泌物量、喷嚏次数、抓鼻次数明显减少;复方双辛喷雾剂还能显著降低豚鼠鼻黏膜中组胺含量(P﹤0.01)。

Allergy which is induced by inhaled allergens group and food allergens group is one of the most important factors causing anaphylactoid purpura.

吸入物和食物过敏原诱导的变态反应是导致过敏性紫癜的重要因素之一。

The results were listed as follows:"Cumiansan" had certain promotion and enhancement to the thickness of foot-plate in DTH, CD4+/CD8+T cell ratio in peripheral blood of the normal and the immunosuppressive mice as well as the normal mice's blood serum TNF-a content, the ultra-fine powder remarkably surpassed the commonly cribble.

结果表明,&促免散&对正常和免疫抑制小鼠足趾变态反应、外周血CD4~+/CD8~+T淋巴细胞亚群的比例以及正常小鼠的血清TNF-α的含量均有一定的促进和提高作用,但与粉体的粒度和剂量有关,微粉低剂量即可达到与粗粉中高剂量相当的效果。

Result: The main ADR of Huangqi injection respectively were allergic reactions , then dermoreaction 9 cases (21.95%), allergic shock 5 cases (12.19%),drug fever 8 cases (19.51%), the respiratory system damage 8 cases (19.51%) and the other system damage 11cases (26.82%).

结果:黄芪注射液所致的不良反应主要为变态反应,其中皮肤反应9例(占21.95%),过敏性休克5例(占12.19%),药物热8例(占19.51%),呼吸系统8例(占19.51%),其他11例(占26.82%)。

Result: The main ADR of Qingkailing injection respectively were allergic reactions , then dermoreaction 40 cases (47.62%), allergic shock 21 cases (25%),drug fever 6 cases (7.14%), the nerve system damage 10 cases (11.90%), the respiratory system damage 5 cases (5.95%) and the blood system damage 2 cases (2.38%).

结果:清开灵注射液所致的不良反应主要为变态反应,其中皮肤反应40例(占47.62%),过敏性休克21例(占25%),药物热6例(占7.14%),神经系统10例(占11.90%),呼吸系统5例(占5.95%),血液系统2例(占2.38%)。

The immune function was evaluated with T lymphocyte proliferation,NK cell activity assay,IgMplaque forming cell assay,blood serum erythrocytolysin assay and delayedtypehypersensitivity to SRBC.

采用T淋巴细胞增殖和迟发型变态反应来评价细胞免疫功能,采用血清溶血素测定和抗体生成细胞检测来评价体液免疫功能,采用乳酸脱氢酶法测定自然杀伤细胞活性来评价非特异性免疫功能。

Besides, to establish a group of nonmedical models. To observe the ethological performance of rats and examine the contents of histamine in nasal nucous coat, nasal secretions; oxyphilic granular leukocytes and total IgE values in blood serum.

方法以卵清白蛋白致敏大鼠制做I型变态反应动物模型,随机分为3组:模型对照组、鼻敏水组、药物对照组,并设正常对照组,分别观察各组大鼠行为学表现及测定其鼻黏膜组胺含量、鼻分泌物和血清嗜酸性粒细胞、血清总IgE水平。

Such as Ligustrum lucidum can promote bone marrow erythropoietin; promote antibody; anti-inflammatory anti-allergic; improving the role of coronary blood flow and blood fat.

如女贞子可促进骨髓造血红细胞生成;促进抗体产生;抗炎抗变态反应;还有改善冠脉流量及降血脂作用。

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