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To develop a method for the culture of OECs and to evaluate the therapeutic effect of OECs transplantation on experimental allergic encephalomyelitis.

目的 研究嗅鞘细胞的培养及其对实验性变态反应性脑脊髓炎的治疗功用。

AIM: To investigate the modification by glucocorticoid on CD4 CD25 regulatory T cells in mice with experimental autoimmune encephalomyelitis.

目的:研究糖皮质激素在实验性变态反应性脑脊髓炎治疗中对调节性T细胞的调变作用。

We tested the mononuclear phagocyte englobement function, serum haemolysin, delayed hypersensitivity, interlukine-1, 2(IL-1, 2) activity and T, B lymphocyte proliferating function.

测定小鼠单核巨噬细胞吞噬功能、血清半数溶血素值、迟发型变态反应、T淋巴细胞及B淋巴细胞增殖能力、白介素-1(IL-1)及白介素-2(IL-2)活性。

Eosinophile, mast cell , basophils, lymphocyte and many kinds of cytokine are involved in this inflammation.

是以气道高反应性和慢性气道炎症为特征的变态反应性疾病,是由嗜酸性粒细胞、肥大细胞、T淋巴细胞等多种炎症细胞和细胞因子参与的气道慢性炎症。

Infant eczema is common in infants allergic skin disease, occurred in two months to one-year-old children, a clinical diagnosis often erosive wet, cheek, and then spread to the trunk, limbs and body, skin rash does not form and so on, since the erythema, papules, HSV development exudate, eschar, desquamative and intense itching as the main characteristics.

婴儿湿疹是婴幼儿常见的变态反应性皮肤病,好发于2个月至1岁的小儿,临床上以糜烂型湿诊多见,面颊、继而蔓延到躯干、四肢和全身,皮疹形态不等,自红斑、丘疹、疮疹发展为渗液、结痂、脱屑和剧烈瘙痒为主要特征。

Results α-Linolenic acid was capable of increasing the quantity of antibody-producing cells and the level of serum hemolysin, promoting the expurgation effect and the phagocytic function of monocyte/macrophage, stimulating...

结果α-亚麻酸能提高小鼠的抗体生成细胞数和血清溶血素水平,促进小鼠的单核-巨噬细胞的碳廓清和腹腔巨噬细胞的吞噬能力,促进小鼠的迟发型变态反应,提高小鼠NK细胞的活性。结论α-亚麻酸具有增强小鼠免疫力作用。

Results There was an markedly efˉfect for astragalus root stimulating the multiplication and transformation of spleen lymphocyte,promoting the delayed type of hypersensitivity,increasing the number of antibody-created cell,enhancing the level of serum hemolysin,promoting the expurgation effect and phagocytosis function of monocyte-macrophage and increasing the activity

结果 黄芪能明显刺激小鼠的脾淋巴细胞增殖、转化作用,促进小鼠迟发型变态反应作用,提高小鼠抗体生成细胞数,提高小鼠的血清溶血素水平,促进小鼠单核-巨噬细胞碳廓清作用,增强小鼠的单核-腹腔巨噬细胞吞噬能力,提高小鼠NK细胞活性。

Results Sheep spleen polypeptides could significantly stimulate multiplication and transformation of mice's spleen lymphocytes; increased markedly the weight of spleen and the thymus; promoted delayed hypersensitivity; increased the quantity of antibody-producing cells; increased the level of serum hemolysin; promoted the expurgation effect and the phagocytic function of monocyte/macrophage and increased the activity of natural killer.

结果 羊脾多肽能使小鼠脾、胸腺增重,明显刺激小鼠的脾淋巴细胞增值,促进小鼠迟发型变态反应作用,提高小鼠抗体生成细胞数,提高小鼠的血清溶血素水平,但促进小鼠单核-巨噬细胞碳廓清作用不明显,增强小鼠的单核-腹腔巨噬细胞吞噬能力,有效提高小鼠自然杀伤细胞活性。

Results There was an markedly efˉfect for astragalus root stimulating the multiplication and transformation of spleen lymphocyte,promoting the delayed type of hypersensitivity,increasing the number of antibody-created cell,enhancing the level of serum hemolysin,promoting the expurgation effect and phagocytosis function of monocyte-macrophage and increasing the acˉtivity of natural killer.

结果 黄芪能明显刺激小鼠的脾淋巴细胞增殖、转化作用,促进小鼠迟发型变态反应作用,提高小鼠抗体生成细胞数,提高小鼠的血清溶血素水平,促进小鼠单核-巨噬细胞碳廓清作用,增强小鼠的单核-腹腔巨噬细胞吞噬能力,提高小鼠NK细胞活性。

Methods Level of delayed-type hypersensitivity, IL-2 of immunized BALB/c mice were determined by footpad swelling,MTT and transfered protective rate of T cells purified by neloy wool were studied with 500LD50 of the bacteria.

方法迟发型变态反应、IL-2分别采用足垫肿胀、MTT法;利用尼龙毛柱纯化免疫的BALB/c小鼠的T淋巴细胞通过尾静脉转移到非免疫小鼠,再用500LD50的STM攻击。

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