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NHD specific immunotherapy could attenuate the production of cytokine IL-4, IL-5 and is effective for treatment in dust acarid allergic rhinitis.

尘螨标准化变应原疫苗免疫治疗是一种有效、安全的治疗常年性变应性鼻炎的方法,可能通过减少机体IL-4、IL-5的生成,从而减轻IL-4、IL-5对常年性变应性鼻炎患者的免疫毒害作用,发挥其调节免疫的作用,进而达到有效治疗常年性变应性鼻炎的作用。

Animals in AR and Dex group were sensitized with egg albumin, and in NC group were treated with normal saline as control. After sensitization and reproduction of AR model, rats in AR group received no treatment, while those in Dex group were treated with dexamethasone(5mg/kg, once a day) for 5 days.

NC组为对照组,用生理盐水替代卵蛋白进行同步处理;AR组为变应性鼻炎无干预组;Dex组为变应性鼻炎地塞米松干预组,动物建模后腹腔注射地塞米松注射液(5mg/kg)治疗,每天1次,连续5d。

The result showed that the MUC5AC may play an important role in the hypersecretion of mucin in patients with perennial allergic rhinitis.

黏蛋白MUC5AC在常年性变应性鼻炎的黏液过度分泌过程中具有重要意义,但是没有发现黏蛋白MUC5在常年性变应性鼻炎的黏液过度分泌过程中起明显作用。

Object: The mechanism and method of the neurectomy were explored in the treatment of e allergic rhinitis.The basic on anatomy and theory was provided for treating allergic rhinitis by surgical way. Methods:A team of Rabbits were made sensitization three days after the sphenoidpalatine nerve was cut or sympathetic nerve was cut.

目的:本研究旨在了解蝶腭神经切断治疗变应性鼻炎的机理和方法,了解感觉神经及其产生的神经肽在变应性鼻炎发病中的作用,了解鼻后外侧神经、筛前神经进入下鼻甲的确切位置,为切断相关神经治疗变应性鼻炎提供理论基础。

2000 outpatients who were doubted with allergic rhinitis by otolaryngologist in Huaxi hospital underwent skin prick test with 10 standardized aeroallergens (Dermatophagoides pteronyssinus, Dermatophagoides farinae; Animal Hair, Feathers, Grasses, Herbs, Moulds I, Moulds II, Tree I , Tree II). The patients were divided into eight age groups(0-10 years, 11-20 years, 21-30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, beyond 70 years).

方法对2005年3月到10月经华西医院耳鼻咽喉科专科医师检查怀疑患有变应性鼻炎的门诊患者(共2000名)进行10种常见吸入性变应原(屋尘螨、粉尘螨、动物毛、羽毛、禾本科花粉、杂草花粉、霉菌Ⅰ、霉菌Ⅱ、树花粉Ⅰ、树花粉Ⅱ)的皮肤点刺试验。

Results Class I allergic rhinitis (without symptoms of secondary barotraumas in flight), class II allergic rhinitis (with symptoms of secondary barotraumas in flight), perenial allergic rhinitis, and pollinosis were diagnosed in 30, 23, 28, and 25 pilots, respectively. Forty-four pilots could continue their flying and 9 pilots were permanently grounded.

结果 飞行人员变应性鼻炎I类(飞行中无继发性气压伤表现)30例,II类(飞行中出现继发性气压伤表现) 23例;常年性变应性鼻炎28例,花粉症25例。44例继续飞行,9例永久停飞。

the incidence of inhalant allergen is higher than ingestive allergen. acaridan is the major allergen in haikou area and thus effective measures be made to prevent the occurrence of allergic dermatosis.

吸入性变应原是海口地区变应性皮肤病主要变应原,其发生率高于食入性变应原,螨是海口市变应性皮肤病的主要变应原,其次为屋尘、猫、狗皮屑。

aeroallergen specific ige antibody in the serum of 625 patients with allergic rhinitis were positive. total ige in serum was positive in 413 cases, accounting for 66.1%. the positive rate of total ige was less than that of aeroallergen specific ige. the positive rate of aeroallergen specific ige in order were mite mixture (84.32%), cockroach (19.04%), cypress (15.20%), cat-dog epithelia (13.12%), tree mixture (7.20%), ragweed (5.12%), humulus lupulus (1.76%), mugwort (1.76%), mould mixture (1.44%). in the two groups, the positive rate of aeroallergen specific ige in order were similar.

625例变应性鼻炎患者中吸入性变应原特异性ige阳性率依次为尘螨84.32%、蟑螂19.04%、柏树15.20%、动物毛皮屑组合13.12%、树木花粉组合7.20%、矮豚草5.12%,葎草1.76%、蒿草1.76%、霉菌组合1.44%;总ige阳性者413例(66.1%)明显低于特异性ige阳性率;两组中最常见的变应原相似;未成年组屋尘螨的阳性率及敏感程度明显高于成年组(p 0.01)。

in the case of AR of children who have obvious allergen, SIT should be more considerable. The curative effect of SIT can be known by the detection of the level of TIgE, SIgE, and ECP in serum of AR patients. SIT of AR makes for prevention and cure of asthma. It is very important for preventing and treating asthma to deal with AR by SIT.

对儿童变应性鼻炎患者有明确变应原者,免疫治疗应予以考虑;检测患者血清TIgE、SIgE和ECP可了解SIT的疗效;对变应性鼻炎进行SIT对防治哮喘有重要意义。

Objective: To investigate the pathogenesis of allergic rhinitis at cell level by determing basophil histamine releasability in guinea-pigs and attempt to find an objective way for the diagnosis of allergic rhinitis.

目的:通过对变应性鼻炎豚鼠的嗜碱粒细胞释放组胺能力的测定,从细胞水平探讨变应性鼻炎的发病机制,并期望为变应性鼻炎的诊断指标提供一种客观手段。

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