变大

To study the changes of plasma endotoxin NO and hemorheology in experimental cirrhotic rats and their correlation,we have used hemorheology analysis system and the means of limulus amoebocyte lystata assay Griess assay to detect changes of plasma endotoxin NO and hemorheological parameter in rats at 3 6 9 weeks after CCl4 administration.

为探讨肝硬化中血浆内毒素、NO水平的变化及血液流变学特性的改变及其相互关系，我们通过用四氯化碳(carbon tetrachloride，CCl_4)来诱导大鼠肝硬化模型，采用鲎试剂动态浊度法、镉还原比色法、血液流变学分析仪，分别检测了大鼠肝硬化演变过程中早期(诱导第3周末)、中期(诱导第6周末)、晚期(诱导第9周末)的血浆内毒素、NO水平及血液流变学各参数。

Fluid strength torque converter although can stepless change the torque in certain scope compared to, but because it exists changes turns between ability and the efficiency contradiction, at present the application fluid strength torque converter generally changes turns the coefficient insufficiently to be all big, satisfies the automobilism request with difficulty, therefore on the high-quality passenger vehicle, widely uses is fluid strength torque converter and the gear type transmission gearbox union composition fluid strength mechanical type variator.

液力变扭器虽然能在一定范围内无级地改变扭矩比，但由于它存在着变扭能力与效率之间的矛盾，目前应用的液力变扭器一般变扭系数都不够大，难以满足汽车使用要求，故在高级轿车上，广泛采用的是液力变扭器与齿轮式变速器联合组成液力机械式无级变速器。

The macroscopic rheological parameters and microstructure parameters were closely related, it is helpful to explain the essence of multiple rheological properties through the analysis of which the wax evolution process and microstructure of the crude oil which is waxy and high viscosity; the yield time of gelled waxy crude oil monotone increases along with the decreasing of rate of shear (the time of stress effect prolonged), there was power function relationship between them, it can be expressed with ; when adding diesel oil to Sudan crude oil, dilute proportion bigger the eccentricity degree of paraffin particles were bigger too, that was to say the symmetry of wax crystal was better, the wax crystal form fabric more hardly when the intermolecular interaction was smaller; in the light of macroscopica, the fall extent of the abnormity temperature, solidifying point and viscosity could be larger along with the accretion of dilute proportion, as a result, it's rheological properties could be improved.

SD原油析蜡点为94℃，析蜡高峰为50～30℃，异常点为40℃；其蜡晶颗粒细小、对称性差，所以具有较大的比表面能，容易形成联生、联锁结构；损耗角曲线与储能模量曲线或损耗模量曲线的交点所对应的温度与原油凝点或倾点温度非常接近，大约在39℃左右；也就是说，含蜡原油粘弹特性曲线的交点可以表征其流动性；原油宏观流变参数与微观结构参数密切相关，原油析蜡过程及蜡晶微观结构分析有助于诠释易凝高粘原油多重流变特性的本质；胶凝含蜡原油的屈服时间随剪切速率的降低而单调增加，二者显然存在幂函数关系，可用关系式描述；当SD原油加柴油稀释处理时，稀释比越高，蜡晶颗粒的偏心度也越大，亦即蜡晶对称性越好，分子间作用力越小，蜡晶颗粒越不易形成结构，宏观表现为异常点、凝点及表观粘度等流变参数下降的幅度越大，流动性越好。

According to the characteristics that Trypanosome can produce different variations, 5 New Zealand rabbits were infected in sequence with a monoclonal strain of Trypanosome evansi isolated from Yunnan buffalo. 50 monoclonal strains were isolated and showed by indirect immune fluorescent test that the first parasitemia peak of variation in following 4 rabbits exist in 9 predominant variations of first rabbit. The 50 variations subordinate to 20 antigen types.

根据锥虫在兔体内可产生不同变异体的特性，将伊氏锥虫云南水牛单克隆株顺序感染五只新西兰大白兔，分离到 50 个单克隆群体，经间接免疫荧光实验证明：后四只兔子出现第一次虫血症高峰的变异体，均包含在第一只兔体内分离得到的 9个优势变异体之内；这 50 个变异体分属于 20 个抗原型，即共分离到 20 个优势变异体。

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果：①40只建模大鼠中36只建模成功，建模成功率为90%；②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现，有6只大鼠在3个月后出现白内障，有4只大鼠在喂养接近至6个月时死亡；③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少，减少约61%(P.01)，后极部视网膜明显变薄(P.01)；④电镜观察，视网膜变薄，视杆细胞膜盘紊乱，血管基底膜增厚等表现；⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达，糖尿病组视网膜组织中3个月时可见少量表达，ERK1/ERK2表达部位为神经节细胞层和内核层；6个月时表达强阳性，部位表达不仅见于内核层、神经节细胞层，色素上皮层也见表达。

To all project practicality, the introduction is given to the operational characteristics, the methods for calculation and the researching actuality of the tail tunnels with sloping ceiling underground hydropower stations the Three Gorges. This paper has discussed in detail the characteristic method being the same with the compressive flow and the Priessmann solution being the same with the free-surface-pressure flow. And how to deal with boundary conditions has been expatiated. Also hydraulic transient process of tremendous load fluctuation in the tail tunnels with sloping ceiling has been numerical simulated and the Fortran program for numerical simulation has been given. The paper gain the maximal press for tail end of the shell, the maximal rising rate of rotational speed of generating set, the maximal vacuum degree for inlet of the tail tunnels and so on under 11 kinds conditions of tremendous load fluctuation. These conditions include the design conditions, the check conditions and the superposition conditions. Finally, the computing results have been analyzed and summarized. The end chapter is the general comment of the whole-length content and the describing of the intending view of researching.

本文以三峡右岸地下电站尾水洞设计为背景，从工程实际出发，阐述了变顶高尾水洞的工作特性、使用范围及其研究现状；详细论述了适用有压流的特征线法、适用明满交替流的普里斯曼解法等数学模型；边界条件的给定和明满交替流的计算方法；用Fonran语言编制了数值计算程序，对三峡右岸地下电站变顶高尾水洞的大波动工况进行了数值模拟，分别得出了在设计工况、校核工况和叠加工况下蜗壳末端最大压力上升值、机组最大转速上升值和尾水管进口最大真空度等重要参数；对数值计算结果进行了详细分析并得出了有价值的结论；最后展望了今后水电站变顶高尾水洞的研究方向。

At the super-low permeable reservior sandstone of Fu and Yang in Daqing Oilfield, many pore throats exist a lot in the types of compacted and restored flakes and curved lamellas while the pore volume of micropore and the thin, compacted and shrunken throat that contribute little to flow take large scale in the total pore space. Thereof high filtrational resistance is caused by much trouble including high content of reservoir shale, serious sensibility to pressure at waterflooding, remarkable effects of undersaturation and water blocks in micropore. A method with laboratory experiment, theoretical confirmation and field application included was adopted to analyze the non-linear flow characteristics, to reveal the deep mechanism of pinhole enveloping macropore and to provide a new technology of improving the development effect. The outcomes aquired are as follows: Multiple cores with different low and super-low permeability were selected to perform seepage experiments by gas, water and oil. Three fields of flow were observed in the reservoir at different low and super-low core permeability. They are pseudo- elastic flow, transition flow and plastic creep flow. So the concept that there was no correlation of rocky absolute permeability with fluid properties that pasted itself was broken up. Two-phase seepage of water displacing oil in uniform super-low permeability shows that the two-phase seepage zone is narrow.

针对大庆油田扶、杨特低渗透油层砂岩孔隙喉道的大小和形态以压实再生型片状、弯片状喉道分布较广，压实、缩小型细喉道型，微孔不可流动的孔隙体积所占总孔隙体积的比例较大的特点；及储层泥质含量高，注水开发中压力敏感性强、微孔隙欠饱和及水锁效应显著，导致流体渗流阻力增大的问题，本文采用室内实验、理论推证和矿场应用相结合的方法，研究、分析了流体非线性渗流特征，更深刻地揭示出小孔包围大孔的机理及产生原因，并提供了改善开发效果的新的技术方法，取得如下成果：选择不同渗透率的低渗透、特低渗透岩心，进行了气、水和油单相渗流实验，揭示出当岩心渗透率不同时，油层内的流体呈现出拟弹性流变、过渡流变、塑性蠕变三种流变区，从而打破了岩心的绝对渗透率与通过岩心流体性质无关的观点；同类特低渗透岩心的水驱油两相渗流实验表明，两相渗流区较窄。

According to the energy conservation theory, BOM and CSIM4 were coupled. The BOM has no treatment on transmission solar radiation, which is of great importance when the model is adapted to Arctic Ocean. So the treatment was introduced to BOM. Through numerical test on different lead albedos, it was found that sea ice thickness is not so sensitive to lead albedo, which may be contribute to the lead occupies little ratio within multiyear sea ice pack. The reason of summer over-melt of arctic sea ice is the NCEP reanalysis downward solar radiation being larger than its reality. Then the arctic sea ice climate variability was simulated. Results showed that: simulated ice thickness change is in accord with the submarine investigated mean sea-ice draft changes. Simulated annually maximum ice thickness along the Eurasian continental oceans are closely related to the observed ones. The long-term mean simulated ice motion has the same features of the SSM/I derived ice motion. Sea ice extents in differential sub-regions have same trends comparing to the satellite passive-microwave data derived ones. Simulated ice concentration is closely related to the observed in the Arctic sub-regions. Sea ice flux through the Fram Strait involves ice concentration, motion and thickness. It is a composite criterion for sea ice model evaluation. The simulated ice area and volume export through the strait accord with the satellite derived or statistically reconstructed ones.(5) The simulated ice thickness climate variability and mean sea surface current of the coupled model were analyzed, results showed: the total ice volume in the Arctic Ocean has a significant decreasing trend. The volume variability is of a 10-year timescale oscillation, with two major periods of 12-13a and 18-20a. Mean ice thickness in the arctic sub-seas has different tendencies. It has an increasing trend in the Barents-Kara Sea and Baffin Bay-Labrador Sea, and decreasing in the others. The characteristic time scale of 7-10a wherein the river discharges leads the Fram Strait ice volume export is about the period that river water takes to be conveyed across the Arctic Ocean.(6) Using the simulated ice distribution in the Arctic Ocean and China precipitation, air temperature and SST in tropical key regions, the climate teleconnection were studied. Result showed: When the mean sea ice thickness is large in the central Arctic Ocean and Chukchi-Beaufort Sea , and small in the Barents-Kara Sea and Baffin Bay-Labrador Sea , the precipitation in South China, Tibetan Plateau, and the north part of Northeastern China are always smaller than normal, and v. v. When the mean ice thickness is small in CA, BC, East Siberian Sea and Greenland-Iceland-Norwegian Sea , and large in BL, The air temperature in north-eastern China, the southern of Tibetan Plateau, and Hainan Island, are always lower than normal, and v. v. In addition, when the sea ice is thick in BC and BL, the SST is larger in the middle and eastern Pacific Ocean, and is smaller in the tropical Southeastern Indian Ocean.

由于BOM没有考虑透射太阳辐射的物理过程，研究表明透射太阳辐射对北冰洋的能量收支起到重要作用，因此在BOM模式中引入了对透射太阳辐射的处理；通过对不同水道反照率的数值试验表明海冰厚度对水道反照率的敏感性不强，可能与海冰区水道面积占的比率很小有关；而模式模拟的北极海冰夏季&过度融化&主要源于NCEP再分析资料提供了偏大的太阳短波辐射；对北极海冰的气候变率进行了模拟研究，结果表明：模拟的海冰厚度变化与潜艇探测的海冰吃深度变化具有一致性；模拟和观测的亚欧大陆沿海的年内最大海冰厚度有很好的相关；模拟的海冰移速与长期平均的卫星反演的海冰移速具有相同的速度分布特征；模拟的各个海区海冰面积的变化趋势与卫星反演资料分析的结果基本一致；模拟与观测的主要海洋分区的海冰密集度具有很好的相关：弗瑞姆海峡的海冰体积和面积的输送涉及到海冰密集度、厚度和移动速度，是判断模式模拟能力的一个综合的指标，模式模拟的结果与卫星反演或重建的面积输送、体积输送具有很好的一致性；(5)分析了模拟的北极海冰厚度的气候变率及气候平均表层海流场，结果表明：北极海冰的总体积有显著减少的趋势，北极海冰总体积的变化具有10a际尺度振荡的特点，存在18-20a和12-13a两个主周期；北极海冰的平均厚度在各个海区的变化趋势不同，在巴伦支—喀拉海和巴芬湾—拉布拉多海地区海冰厚度有显著的增加趋势，而其它海区存在减少的趋势；通过对模拟的气候平均表层海流的分析表明，北极河流流量超前弗瑞姆海峡海冰流量7-10年的特征时间尺度与表层海流的气候分布存在着必然联系：(6)利用模拟结果以及中国降水、气温和热带关键区SST资料，讨论了北极各海区海冰平均厚度与中国降水、气温以及热带关键区SST的关系，结果表明：在北极中心海区和楚科奇—波弗特海海冰厚度偏大，在巴伦支—喀拉海以及巴芬湾—拉布拉多海海冰厚度偏小，则中国降水在华南地区、青藏高原和东北北部降水偏少，反之相反；在北极中心海区、东西伯利亚海、楚科奇—波弗特海以及格陵兰海海冰厚度偏小，在巴芬湾—拉布拉多海海冰厚度偏大，则在中国东北地区、高原南部地区和海南岛附近气温偏低，反之相反；另外，北极楚科奇—波弗特海和巴芬湾—拉布拉多海海冰厚度偏大时，在热带中东太平洋海温偏高，而在热带东南印度洋海温偏低。

METHODS: Adjuvant-induced arthritis rats were treated with acupuncture therapy, Chinese herb treatment or both in combination for one week, then the density of TMPH in heart, liver, kidney, and hind paw was determined by HPLC. The cAMP level in the heart and liver was also measured by radioimmunoassay. The blood changes were detected through the test of blood rheometer.

以佐剂性关节炎大鼠为模型，观察单纯针刺法、单纯药物法及针药结合法分别连续治疗一周后，用HPLC法测定各组大鼠心脏、肝脏、肾脏及病灶局部组织中盐酸川芎嗪的含量；用放射免疫法测定各组大鼠心脏、肝脏中cAMP水平；用血液流变仪测定各组大鼠的血液流变学变化。

On the basis of analyzing the thermodynamic properties and cycle performance of pure refrigerants, the paper optimizes their concentration while screening NARMs used in wide variable-temperature heat source. The practical applications of NARMs, such as R22/R123, R123/R125 etc., are studied in geothermal heat pump, seawater heat pump, air dehumidification system and dual-evaporator domestic refrigerator. The results show that the NARMs can match the limitation of a pinch point at the air-side exit of heat exchanger, reduce the unreasonable heat transfer temperature difference, and improve the COP of system. The above conclusion is proved by measuring the cycle performance of R12, MP39 and R11/R22 in a two-evaporator experimental system.

其次，本文在工质热物性和变工况循环性能分析基础上，筛选和优化了适应外部大变温热源约束条件的非共沸混合工质及其浓度配比；讨论了相变温差较大的非共沸混合工质（如R22/R123、R123/R125等）在地热源供热热泵、海水源供热热泵、双门冰箱和热泵空气除湿的应用，计算分析表明制冷与热泵系统采用相变温差较大的非共沸混合工质有利于弱化传热过程的&窄点&的约束，减小传热过程中的不合理温差，提高系统COP值；通过建立双蒸发温度循环系统试验装置，对R12、R22/R11和R22/R152a/R124循环性能进行实验研究，结果与理论分析一致。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐