变型的

Currently activities involve (1) Investigation of dye-DNA interaction by using spectroscopic methods to probe the binding sites between chromophore and DNA and to identify various DNA conformational structures, particularly the telomeric DNA;(2) Investigation of the structure-activity correlation of anti-telomerase agents;(3) Design and synthesis new compounds for antitumor agents and fluorescence biomarkers;(4) Monitoring the folding and unfolding of quadruplex structure, tracing the pathway of drug delivery and probing drug-target interaction by using single molecule microscopy and spectroscopy.

目前 的研究重点分别是(1)利用光谱方法探讨探针分子与DNA的交互作用，特别是作用位置与结构变化；(2)研究抗端粒酵素作用分子之结构与生物活性之关系；(3)设计及合成抗肿瘤药剂或萤光生物标记；(4)建立单分子萤光光谱与影像技术，研究 DNA的多变型结构之变化机制，监测药物输送的路径过程及其在细胞中与标的物的作用。

Addressing to deficiencies of this method,optimum partition method which is widely used in mass analysis is developed to fit thermocline boundary calculation.

针对垂直梯度法的不足，引入水团分析中的最优分割法，对典型剖面，以及边界型、逆变型、多层型等几类特殊剖面的跃层边界分别进行了计算，并对垂直梯度法与垂直梯度法的计算结果进行了比较分析，结果表明最优分割法确定的跃层边界更为合理。

This is the essential thing: that Western man has been drawn for three centuries to the task of telling everything concerning his sex; that since the classical age there has been a constant optimization and an increasing valorization of the discourse on sex; and that this carefully analytical discourse was meant to yield multiple effects of displacement, intensification, reorientation, and modification of desire itself.

这就是西方人三个世纪以来，被牵引着坦白有关于性的一切事情的真相；是古典时代以来，性话语不断优化，稳固增长的真相；而且这种经过审慎分析的话语意味着可以产生出置换，强化，重取向，以及欲望自身的变型等多重效用。

In order to understand the drug resistance mechanism of HIV-1 integrase mutually existed for multiple drug-resistant strains to the most potent IN inhibitors diketo acids, three S-1360-resistant HIV-1 strains were selected and molecular docking and molecular dynamics simulations were performed to obtain the inhibitor binding modes.

为了解DKAs引起的多种耐药株共有的耐药性机理，选择3种S-1360引起的IN耐药突变体，用分子对接和分子动力学模拟，研究了野生型和突变型IN与S-1360的结合模式，基于该结合模式探讨了3种耐药突变体所共有的耐药性机理。

Eighthly, as one of the country in which economic system is turning to another system, China is fully creative during the course of the birth and growing of socialistic market economy system. In the process of the turning of economy system, the turning of accounting realizes. It builds solid foundation for the development of modern accounting system of China, and will promote the development of modern accounting system persistently in the following further economic reform.

八是在当代经济体制转轨国家中，中国在社会主义市场经济体制建立与发展之中，凸现了它的创新方面，并在实现经济体制转轨的改革中，实现了会计的转轨变型，建立了中国现代会计体系发展的基础，并将在今后深化经济改革中进一步推动现代会计体系的持续发展。

With the development of science and technology especially information technology, the conventional steady market becomes much dynamic and mutative. For its much advantages beyond mass production, Mass Customization is turning into the main production pattern of manufacturing industry.

随着科技的进步，特别是信息技术的发展，世界市场已从传统的相对稳定型市场演变为动态多变型市场，大规模定制由于克服了大批量生产方式的诸多缺陷，成为制造业发展的必然趋势。

Based on the fundament of analyses of abroad and our country CNG engine technology, the developing strategy of CNG engine has suggested. Based on the EQD180-20 diesel which the basic construction unchanged, the necessary modified designing for CNG engine was made which included combustion system, intake and exhaust system, cylinder head, piston, and turbocharger.

在分析国内外天然气发动机技术的基础上，提出了满足国3排放的电控喷射单燃料CNG发动机开发方案；以EQD180-20柴油机为基础机型，在基本不改变原机结构的前提下，对燃烧系统、进排气系统、气缸盖、活塞和增压中冷系统进行相应的变型设计；采用稀薄燃烧、增压中冷、低涡流燃烧系统、电控分组点火、开环控制、电控CNG喷射系统和氧化型催化器等技术，降低排放，保持天然气发动机的动力性和经济性。

S where 3-EtO-SalAPA is the monoanionic Schiff base derived from 3-ethoxysalicylaldehyde and N-(3-aminopropylaziridine and S is C6H5F, C6H5Cl, C6H5Br, C6H5I or o-C6H4Cl2. Their gradual nature of spin-state interconversion is evidenced by the variable-temp. magnetic susceptibility and EPR data. Only a single quadrupole-split doublet is seen in the Moessbauer spectra for all solvates in the temperature range of

本文对五种组成为[Fe(3-EtO-SalAPA)2]ClO4.S的Fe自旋变异晶态配合物进行了磁学和谱学表征，所有溶剂合物的变温磁化率和EPR数据证示它们的自旋态转变性质均属渐变型，在110-300K范围内的Mossbauer谱都只显示单一的四极分裂双峰。

With the increasing of the detritus content of rock masses（from mud shale, siltstone, to fine and medium sand）, the compressive strength and elastic modulus of rock masses increase.

试验研究与理论分析结果表明，随着碎屑颗粒含量的增加，岩石的强度和刚性增强，受载过程中积蓄的弹性应变能增大而耗散的永久变形能减少，发生应变型冲击地压的可能性增加。

The plane-parallel resonant cavity is built up in theory with the U-shaped bending waveguide for TM mode. The beam splitting and convergence effect are also discussed for the structure composed of filling-factor graded wave-like 2D-PC and one-dimensional multilayer thin films.

利用TM模的U型转弯波导构建了新型的平行平面谐振腔，并指出由填充率渐变型波状结构二维光子晶体和一维多层薄膜构成的混合结构在光分束和抑制光束发散方面的作用及其在平行平面谐振腔中的潜在应用。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。