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But the existence, structure and localization of plant GABA receptors are needed to be further studied all the same.GABA could decrease relative exosmic ratio of radicle and coleoptile, enhanced the content of endogenous soluble sugar, proline and betaine, promoted the absorb of K+, excluded Na+ coming in the root, stem and leaves of maize seedling, increased K7 Na+ ratio under salt stress.

GABA类似物及动物GABA受体拮抗剂能够略微减弱GABA的生理学效应,动物GABA受体激动剂略微增加GABA的生理学效应,暗示植物可能也象动物一样存在GABA受体

The properties of several rhodopsin sequences were analyzed by comparing withα2A-adrenergic receptor, and a great similarity was found between bovine rhodopsin andα2A-adrenergic receptor. Therefore transmembrane helices ofα2A-adrenergic receptor were constructed homologically based on the bovine rhodopsin.In the newly constructed structure, a 0.090 nm3 active-site, which was enclosed by several reported active residues, was found.

通过对比多个与α2A-肾上腺素受体同属G-蛋白偶联受体的视紫红质蛋白序列,选择以相似性最大的牛视紫红质蛋白为模板,同源模建了α2A-肾上腺素受体的跨膜结构,并在结构中找到了体积为0.090 nm3,已被报导的活性残基包围的活性位点。

Besides neurokinins, recently we found that the dominant opioid receptor, delta subtype, was existed in renal pelvis and intrapelvic activation of DOR resulted dose-dependent increases in ANRA, suggested that DOR plays a role in regulating renal sensory response.

除了神经激肽受体之外,本实验室最近也发现类鸦片受体在肾盂表现并且其中以delta亚型的类鸦片受体(delta-opioid receptor, DOR)为主,活化肾盂内DOR可够剂量依存性地增加传入性肾神经的活性,所以DOR可调控肾脏感觉功能。

Objective To study the effects of angiotensin Ⅱ receptor antagonist valsartan on intrarenal mRNA expressions of ETA and ETB in diabetic rats.

目的 观察血管紧张素受体拮抗剂缬沙坦对糖尿病大鼠肾脏内皮素受体A、内皮素受体B基因表达的影响。

Two classes of renal sensory receptors have been identified neurophysiologically: renal mechanoreceptors responding to increases in intrarenal pressure and renal chemoreceptors responding to renal ischemia and/or changes in the chemical environment of the renal interstitium.

在电生理的研究下,有两类的肾脏感觉受体被发现,分别为:感应肾脏内压力的肾压力性受体;及感应肾脏缺血及肾内化学环境改变的肾化学性受体

Extant jawless vertebrates, represented by lampreys and hagfishes, have innate immune receptors with variable domains structurally resembling T/B-cell receptors. However, they lack cardinal elements of adaptive immunity shared by all jawed vertebrates: T/B-cell receptors and major histocompatibility complex molecules.

在以七鳃鳗和盲鳗为代表的无颌类脊椎动物中,虽然发现了与有颌类脊椎动物T细胞受体(T-cell receptors, TLRs)、B细胞受体(B-cell receptors, BCRs)可变区具有相似结构的先天性免疫受体,却从未发现有颌类脊椎动物适应性免疫系统的核心组分:TCRs、BCRs、组织相容性复合体(Major histocompatibility complex, MHC)。

The proximal jejunum of the graft was anastomoscd to that of recipient, and an jejunostomy was created by exteriorizing the distal end of the donor jejunum with the recipient distal jejunum anastomosed to the side of the graft blow the stoma.

肠道重建采用切除受体部分回肠,将供肠近端与受体肠近切端端端吻合,供肠远端与受体肠远切端端侧吻合后把供肠远端拖出,腹壁造口的方法。

The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明,SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达,孔圣枕中丹组比盐酸哌甲酯组要高,且两者均低于对照组;豆状核多巴胺受体D2的基因表达,盐酸哌甲酯组要比孔圣枕中丹组高,且均低于对照组。

Seen from clinical effect, haemodynamics and general condition both better in rats treated with dexamethasone than rats treated with saline. We had a presumption on these grounds that the sum of negativity myodynamia generated byβ3-AR up-regulation andα1-AR down-regulation possibly less than positive myodynamia generated byβ1-AR up-regulation. 5 For patients with DCHF, adding prednisone to the usual care resulted in significant relief of the congestive symptoms, which was accompanied with a potent diuresis with time and an improvement in renal function.

从临床效果来看,地塞米松治疗的心衰大鼠在血流动力学及一般状况上,都明显优于注射生理盐水的心衰大鼠,据此推测,β3受体上调和α1受体下调产生的负性肌力之和可能弱于β1受体上调产生的正性肌力。5对于失代偿的充血性心力衰竭病人,在心衰常规治疗基础上加用强的松这种糖皮质激素能显著缓解充血症状,并伴随着强有力的利尿和改善肾功能的作用。

Results Many neuronal cell bodies and fibers with dense mGluR7-like immunoreactivity were intensely distributed in the island of Calleja,hippocampus,dentate gyrus,medial habenular nucleus,olivary pretectal nucleus,zonal layer of the superior colliculus,superficial layers of the caudal spinal trigeminal nucleus,paratrigeminal nucleus,raphe magnus nucleus,raphe nucleus pallidus,locus coeruleus,superficial layers and lateral spinal nucleus of the spinal cord.

近年来,大量生理学和药理学实验表明,Glu还可通过与G蛋白偶联的一类受体来调节兴奋性突触的活动和神经元的兴奋性,此类受体被命名为代谢型谷氨酸受体(metabotropic glutamate receptors,mGluRs)。目前应用分子生物学技术已成功地克隆出mGluR的8种亚型(mGluR1-8)[2~7]。

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