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Agmatine is a novel neurotransmitter and/or neuromodulator, which is the endogenic ligand of the imidazoline receptors.

胍丁胺是一种新的神经递质和/或神经调质,是咪唑啉受体的内源性配体。

The anti-cancer effect of these hormones by increasing endorphin second step is to directly activate cells of the opioid receptor.

这些激素的抗癌作用的第二步是通过增加内啡肽直接激活癌细胞的阿片受体

Objective To investigate the role of endotoxin receptor expression in the activation of hepatic stellate cells.

目的 了解内毒素受体在肝星状细胞活化中的变化和作用。

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果: 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高,4小时吞噬能力达最高峰,8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8,但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论: 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的,并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应,对哮喘炎症的控制具有重要意义

The galanthus nivalis agglutinin is one kind of plant mannose combine agglutinin, it can integrate on the glycoprotein acceptor of insect enteron epithelial cell, and produces partial or system poisons to the insect and suppresses its growth.

雪花莲凝集素是目前与害虫治理有关且研究得比较多的一种单子叶植物甘露糖结合凝集素,能结合到昆虫消化道上皮细胞糖蛋白受体上,对昆虫产生局部或系统毒害后果,抑制害虫生长发育繁殖。

Small intestinal biopsies showed subepithelial collagen deposition with varying degrees of villous atrophy and varying numbers of intraepithelial lymphocytes. Four patients had previous biopsies showing enteropathic changes without collagen deposition. Seven cases were associated with collagenous colitis and 1 also had features of lymphocytic colitis. Three patients also had collagen deposition in gastric biopsies. One case was associated with lymphocytic gastritis. Celiac disease (CD, gluten-sensitive enteropathy) was documented in 4 patients. Five patients made a clinical improvement with combinations of a gluten-free diet and immunosuppressive therapy. Two patients died of complications of malnutrition and 1 of another illness. Clonal T-cell populations were identified in 5 of 6 cases tested. Four of these patients improved clinically after treatment but 1 has died. Collagenous sprue evolved on a background of CD in 4 cases. There was no history of CD in others and these cases may be the result of a biologic insult other than gluten sensitivity.

小肠活检表现为上皮下胶原沉积,绒毛萎缩程度不一,上皮内淋巴细胞浸润数量不等。4例患者以往曾做过活检,表现为其他肠病改变,并没有胶原沉积。7例患者合并胶原性结肠炎,且1例还有淋巴细胞性结肠炎的特征。3例患者胃活检也发现有胶原沉积。1例患者合并淋巴细胞性胃炎。4例患者有乳糜泻(CD,谷蛋白敏感性肠病)病史。5例患者经无麸质饮食和免疫抑制治疗后,临床症状有所改善。2例患者因营养不良合并另一种疾病而死亡。6例患者做了T细胞受体基因重排,其中5例发现有克隆性T细胞群,这5例中有4例治疗后临床症状加重,且1例死亡。4例患者在CD的基础上病发胶原性口炎性腹泻;其余患者无CD病史,他们的发病也许是生物源性损害,而非谷蛋白敏感。

Aims: To observe the effect of antagonists of various 5-hydroxytryptamine (5-FIT) receptors on gastric slow waves and energy of pacing stimuli needed to entrain gastric slow waves, and hence to investigate the mechanisms of gastric pacing in rats.

目的:观察不同5-羟色胺(5-HT)受体拮抗剂对胃慢波和控制胃慢波所需的刺激能量的影响,探讨胃起搏的作用机制。

Effects of in vitro maturation duration and enucleation time of buffalo oocytes on the NT embryo development were studied.

探讨了受体卵母细胞的成熟和去核时间对水牛核移植效果的影响。

Methods 1. HE staining. Cells were stained by hematoxylin and eosin, observed under light microscope.

细胞传代后,平均细胞于各皿中,分别加入不同浓度的AngⅡ和CGP-42112A(特异的AT〓受体激动剂)诱导细胞,在不同时间进行观察。

Bronchial asthma;cold type asthma; heat type asthma; IgE;SIL -- 2R; T -- lymphocyt subpopulations; Eosinophile lung function;clinical study

支气管哮喘;冷哮证;热哮证;IgE;可溶性白细胞介素Ⅱ受体;T淋巴细胞亚群;嗜酸粒细胞;肺功能;临床研究

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

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