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It is postulated that IP induces the release of endogenous protective molecules that interact with cognate receptors to activate PLC through mediation of the chincough virus sensitive proteins. PLC hydrolyzes membrane phospholipid and produces diacylglyccerol,that,by working together with calcium hydronium,translocates PKC from cytoplasm to cell membrane and activates PKC.

推测缺血预处理细胞保护作用机制是:缺血预处理引起内源性保护物质释放,作用于细胞膜上的相应受体,通过百日咳病毒敏感性G蛋白的介导而激活磷脂酶,磷脂酶水解膜磷脂,产生二酰基甘油(diacylglyccerol,DAG),DAG和Ca2+协同作用于PKC,使其从胞浆转位到细胞膜并且被活化,PKC在膜上使底物蛋白磷酸化,引发一系列相关信号转导通路的激活,调控保护性基因的表达,从而提高细胞对缺血再灌注损伤的耐受性。

Cholecystokinin , firstly identified as a gastrointestinal peptide, is wildly distributed throughout the centr...

CCK是一类典型的脑肠肽,在中枢神经系统以神经递质或调质的形式,通过其受体发挥重要作用。

This conservation of a regulatory network supports the homology of metamorphosis in the chordate lineage.

因此,由甲状腺素诱导的变态过程受到了甲状腺素受体的调节,这种变态过程是所有脊索动物的祖先特征,这种调节网络的保守性也支持变态在脊索动物谱系中是具有同源性的。相关论文发表在《当代生物学》上。

Objective This study was conducted to detect the expression of laminin and laminin receptor in the specimens of hydatidiform mole, invasive mole and choriocarcinoma, respectively.

目的 了解葡萄胎、侵蚀性葡萄胎和绒毛膜癌组织中层粘连蛋白及其受体的表达,并探讨LN、LN-R与妊娠滋养细胞肿瘤侵袭和转移的关系。

Results Stain for EGFR was detected in all cell types of trophoblasts in GTD and normal chorion villi.

目的 研究表皮生长因子受体在妊娠滋养细胞疾病的表达,探讨EGFR对预测葡萄胎恶变的价值。

Recently,many articles reported the close correlation between human height and gene polymor- phism,such as GH1 gene, VDR gene ,CYP19 gene,estrogen receptor gene and a few regions in the Y chromo- some.

GH1基因、 VDR基因、CYP19基因、雌激素受体基因以及Y染色体均与人的身材高矮有密切联系。

In that case, the chromophore plane of TMB is nearly perpendicular to the substrate surface with its long axis lying on the substrate.

在这种薄膜中,给体和受体以面对面的方式堆积,两者的环平面与基片平面接近垂直。

Chronobiology ; circadian rhythm ; yeast two-hybrid ; laminin receptor ; Period1 gene

时间生物学;生物节律;酵母双杂交;层粘连蛋白受体; Period1基因

The reaction of α-hydroxyketone with Michael acceptor nitroalkene.was studied. After many experiments, we then found that in the presence of Zn2 and cinchonine, the α-hydroxyketone could successfully react with nitroalkene. Under our optimized condition, we gained the 95% yield of product with the ratio of syn : anti of 3:1 and 72% ee value for syn-product.

有机碱作用下α-羟基酮对硝基烯烃的加成反应研究研究了α-羟基酮类化合物与Michael受体硝基烯烃类化合物的反应,通过分析和实验发现在Zn2和辛可宁的作用下α-羟基苯乙酮能够与硝基烯烃化合物顺利反应,在优化的条件下以95%产率和3:1的Dr主要得到顺式产物,其中顺式产物的ee值最高为72%。

We know that this receptor is involved in regulating the formation of cortical circuitry.

我们知道这是受体参与调节形成皮层电路。

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