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Now present evidence that a family of proteins related to ionotropic glutamate receptors is a previously unrecognized class of odorant receptors.

现在,有证据证实一类与离子型谷氨酸受体相关联的蛋白(先前的研究未将其定位为受体)是气味受体家族中的一类。

Rats with CHF were divided randomly into two groups, one group was injected dexamethasone(1mg /kg) intramuscularly at the first and forth day respectively,the other group was injected equi-volume saline likewise, and observing the changes of symptoms of rats with CHF; measuring rats hemodynamics index including blood pressure, heart rate and left ventricular end-diastolic pressure 4 days later. Part 2: To measure every group rats myocardialα1、β1、β2、β3-AR density by immunohistochemical method ,and to understand the AR density changes .Taking the first part rats'myocardium tissues for testing myocardialα1、β1、β2、β3-AR density and 5 normal rats for normo-contrast group and taking gray scale of slice as AR density. Part 3: The study enrolled 35 patients with DCHF. Patients were included if they had orthopnea and refractory edema due to acute DCHF that was severe and had taken more 1 week hospitalization and intravenous therapy in addition to diuretics.

观察心衰大鼠的症状,4天后对两组大鼠进行血流动力学检测,检测指标包括血压、心率和左室舒张末压;第二部分:取第一部分实验动物大鼠的心肌组织,并取5只正常大鼠的心肌组织作为正常对照,用免疫组化法检测大鼠心衰前后及糖皮质激素治疗前后大鼠心肌组织肾上腺素能受体α1、β1、β2、β3受体的变化,取镜下切片的灰度值反应受体的密度;第三部分:研究对象为临床难治性心衰病人35例,病人的选择标准包括由于急性失代偿的心力衰竭出现的端坐呼吸,难治性水肿,患者病情严重,住院超过1周,包括利尿剂之外药物的静脉治疗。

The experiment of privates providing public goods includes subjects, initial endows, providing mechanism and payoff function, the reason that the practical voluntary contribution excels the dominant equilibrium is human behavior with homo-economics, including pure altruism, warm-glow effects. reciprocal, conformity effect and noise; Reducing the contribution cost may improve the level of voluntary contribution, incentive mechanisms include dynamic game, stake distribution, encouragement and punishment, symmetrical information, communicating each other and re-grouping.

公共产品私人提供实验一般包括实验受体、初始禀赋、供给机制和支付函数等,公共产品私人提供偏离占优策略均衡主要是因为人的行为对利己、理性的背离,包括利他主义、光热效应、互惠行为、遵奉效应以及噪音或决策失误等;而通过降低公共产品的私人贡献成本可以提高公共产品私人贡献水平,这种激励机制主要包括博弈动态化、合理分配赌注、建立奖惩机制、公开贡献信息、受体相互交流以及受体重新分组等。

The binding between PCL and its receptor was formed by interaction of protein and earbohydrate.

在红花菜豆的抽提液中,用蛋白质印迹的方法发现存在多个PCL受体受体与PCL的结合是通过PCL肽链蛋白质与受体的寡糖相互作用的结果。

The effect of progesterone could be potentiated by GABA A receptor agonist muscimol and antagonized by GABA A receptor antagonists bicuculline and picrotoxin as well as GABA B receptor agonist baclofen. The effect of progesterone and the actions of these drugs mainly manifested in the concentration range of progesterone 0 01~0 05 μmol/L.

该作用可被氨基丁酸A受体激动剂蝇蕈醇加强,被氨基丁酸A受体拮抗剂荷包牡丹碱和印防己毒素以及氨基丁酸B受体激动剂巴氯芬阻断,而且孕酮的效应以及各药物对其的影响均集中在0.01~0.05 μmol/L孕酮浓度中较为明显。

In another series of experiments, we have observed that the effects of i. t. picrotoxin (PTX, a non-competitive GABA〓-receptor antagonist), or bicuculline (BIC, a competitive GABA〓 receptor antagonist), on the antinociception produced by i. t. NE, 5-HT or a GABA〓 receptor agonist muscimol using behavioural method.

在第二系列的实验中,我们使用行为测痛的方法观察了鞘内注入非竞争性〓受体阻断剂印防已毒素和竞争性〓受体阻断剂荷包牡丹碱,对鞘内注入NE、5-HT和〓受体激动剂muscimol所引起的镇痛作用的影响。

DC takes up antigen through phagocytosis, pinocytosis, and endocytosis via different groups of receptor families, such as C-type lectin receptors for antigen capture and presentation, Toll-like receptors for pathogen recognition and DC activation.

DC通过不同的受体吞饮、吞噬和胞吞抗原,例如C型凝集素受体捕获和呈递抗原,通过Ton样受体识别病原体和激活DC。

Radio-ligand binding assay was applied to determine the maximum binding and affinity changes of nicotinic acetylcholine receptor on five weeks old male Sprague-Dawley rat's lateral pterygoid muscle and superficial masseter muscle after the function mandibular advancement.

本研究在以往研究的基础上,首次对功能矫形的神经肌肉调控机理进行探索。应用放射受体分析法,从膜受体蛋白分子水平定量研究功能矫形前伸青春期SD大鼠(5周龄)下颌后,下颌前伸肌细胞膜烟碱样乙酰胆碱受体最大结合容量和亲和性的变化。

This suggested that the mechanism of alleviating asthma was that when drugs were combined with the active part ofβ2 receptor ,the conformation of receptor was changed and receptor was activated,spasm of bronchial smooth muscle was alleviated,of which relieved edema of air passage、restrained inflammatory cell and so on,these would contribute to pursiness.

这表明,麻杏石甘汤的平喘机制应该是通过和β2受体活性部位结合,改变了受体的构象,受体被激活,使得支气管平滑肌松弛,减轻了气道水肿,抑制了炎症细胞等,有利于缓解和消除喘息。

Further study suggested that the D-serine produced in astrocytes regulates the function of NMDA receptor through the glycine-binding site of the receptor.

这种内源性D-Ser在神经系统中的分布与NMDA受体的分布相平行,进一步的研究表明,D-Ser由突触旁星形胶质细胞产生,而作用于突触后NMDA受体上的Gly结合位点,对NMDA受体的功能进行调控。

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