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In the mouse,genetic studies show that the MC1R appears to be a unique,bifunctionally controlled receptor,activated by α–MSH and antagonized by agouti,both of which contribute to the variability seen in mammalian coat color.

MC1R基因的变异与动物的皮毛、人的皮肤和头发颜色差异密切相关。对小鼠的遗传学研究显示,MC1R是独特的、双功能控制受体

Objective To investigate the effects and mechanisms of BP on P53, P21 and AhR pathway of HELF cells in vitro.

目的 研究苯并芘对体外培养的人胚肺成纤维细胞中P53、P21蛋白量的影响及芳烃受体途径的作用。

However, chronic repetitive administration of beta-adrenoceptor agonists may increase AHR, airway inflammation, and risk of death.

然而长期反复使用β受体激动剂也可能增加气道高反应性、气道炎症和死亡的风险。

However,chronic repetitive administration of beta-adrenoceptor agonists may increase AHR, airway inflammation, and risk of death.

但持续使用β-肾上腺素受体激动剂可能会增强AHR,扩大炎症反应,增加死亡率。

AhR activated by environmental pollutants modifies a series of gene expression involved in cell proliferation, cell cycle and apoptosis, which cause injury and cancer.

环境污染物同时可激活芳基烃受体并改变一系列与细胞增殖、细胞周期进程和凋亡相关基因的表达,导致机体损伤并诱发肿瘤。

The toxicity of dioxins is dependent on their affinity to AhR. And if this affinity data would be gotten, we could know their harm degree and have ability to analyze and control these toxins quickly and effectively.

Dioxins与受体AhR相互作用的强弱决定着化合物毒性的大小,如能获得化合物对AhR的亲和性,就可以了解其危害程度,从而为快速有效对毒物进行分析及控制提供条件。

Objective To explore the possibility of aldosterone biosynthesis and expression of aldosterone receptor in rat mesangial ceils in vitro.

目的 探讨培养的大鼠肾小球系膜细胞能够自身合成分泌醛固酮及存在醛固酮受体的可能性。

The change of aldosterone and its receptors in kidney can affect the process of renal fibrosis in SHR.

肾组织醛固酮及其受体水平的改变可能影响高血压肾脏纤维化的过程。

Receptors for GA and ABA had been localized on the aleurone cell PM.

GAs和ABA的受体位於质膜上。

To discuss the effects of recombinant soluble alexin receptor type Ⅰ(sCR1) on complement expression in acute spinal cord injury tissue of rats and the protection of it on spinal cord injury.

目的探讨重组可溶性补体受体Ⅰ型(sCR1)对大鼠急性脊髓损伤组织补体表达的影响及对脊髓损伤的保护作用。

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