受体

I found that activations of GABA_ARs and GlyRs inhibit the activities of two receptors in a region-specific manner.

结果显示，激活GABA_A和甘氨酸受体导致区域特异性的相互抑制，即在这三个区域这两种受体之间对话的模式是不一样的。

This contracting effect of NE on BA could be augmented by β-adrenoceptor antagonist propranolol (10〓mol/L)(there was no this augmenting effect in RA) and could be antagonised by α〓-adrenoceptor antagonist prazosin but couldn′t be antagonised by α〓-adrenoceptor antagonist yohimbin (10〓mol/L).

这说明AVP引起的收缩在BA对胞外钙的依赖性明显大于RA，提示与V〓受体耦联的胞内钙池在BA明显小于RA。因此，血管活动的个血管活动的个性现象绝不仅仅是受体分布的差异所致。

The majority of BA tested didn′t contract to NE, only a small number of BA contracted to NE but with obvious lower afficacy, lower affinity and tachyphylaxis to NE than RA.

按研究BA和RA平滑肌V〓受体时我们发现，尽管BA和RA在V〓受体的分布上没有差别，但在无钙介质中，AVP引起的收缩在BA则被明显抑制，而在RA则仅被轻度抑制。

The results showed that (1) all the arteries tested had tachyphylaxis to peptidergic agonists;(2) the desensitization of the arteries tested to catecholamines was uneasy except BA;(3) the desensitizations to AⅡ, AVP and PE were homologous;(4) the endothelium-EDRF -cGMP pathway had no contribution to the tachyphylaxis of PA to AⅡ and AVP;(5) membrane receptor cycling (internaliation and re-insertion) contributed only in part to homologous desensitization;(6) there was no change in the function of voltage-dependent Ca〓 channel during desensitization to AⅡ and AVP;(7) some changes in G protein occurred during homologous desensitization;(8) the most surprising finding was that the caudal arterial smooth muscle of stroke-prone spontaneously hypertensive rat showed tachyphylaxis to α〓-adrenoceptor agonist PE, while the tachyphylaxis of pulmonary artery of SHR was not changed compared with that of Wistar rat.

脱敏是消除效应的一种有效方式。因此，研究不同血管对不同激动剂脱敏的差异及阐明脱敏的机制，有助于阐明血管活动个性化的机制。研究表明：血管对肽类激动剂的脱敏方式为快速脱敏，而对儿茶酚胺类激动剂不易脱敏；血管对肽类激动剂和儿茶酚胺类激动剂表现为同源脱敏；内皮-NO-cGMP通路不参与肺动脉对AⅡ和AVP的快速脱敏；用PAO抑制膜受体的内在化只能短暂抑制脱敏的发展，提示用膜受体数目的下调说不能完全解释同源脱敏；血管对AⅡ和AVP脱敏后VSMC细胞膜电压依赖性钙通道功能无改变；CA对AVP脱敏后GTPγS的量-效曲线下移，说明有G蛋白的变化，但这种变化并非G蛋白的亲和性改变；SHRsp之CA平滑肌对AⅡ和AVP的快速脱敏并未减弱，但对PE却表现为快速脱敏，这是我们首次发现的一个非常有趣的现象。

For this reason, treatment should be emphasized on the regulation of endocrine in male patients, while in female patients the more attention should be paid to the modulation of the numbers and function of the local SHR. for female.

因此我们认为：在临床治疗上男性患者应侧重于内分泌调节的治疗，而对于女性患者应侧重于找出其局部受体改变的原因，并以改变局部受体的数量及功能的治疗为主。

This has changed with the recent discovery of the lymphatic endothelial markers vascular endothelial growth factor receptor 3, LYVE-1 (a lymphatic endothelium-specific hyaluronan receptor), Prox 1, and Podoplanin.

直到近期，一些淋巴管内皮细胞的标志被发现才被承认，如血管内皮细胞生长因子受体3（VEGF-3），LYVE-1（一直淋巴管特异性的透明质酸合成酶受体），Prox 1和Podoplanin 方法：因此，我们总结了关于角膜新生淋巴管存在的依据及其分子标志和调节因子。

Objective To study estrogen receptor and estrogen receptor messenger RNA expression in gastric carcinoma and to investigate the relationship with gastric carcinoma biological behaviors.

目的研究雌激素受体、雌激素受体mRNA在胃癌中的表达，以探讨其与胃癌生物学特性的相关性。

Background and objective Peroxisome proliferato-activated receptor-gamma is a kind of nuclear hormone receptor, which plays important roles in regulating metabolisms.

背景与目的过氧化物酶体增生物激活受体是对机体代谢过程起重要调节作用的一种核激素受体。

In SGK321 with expression of CpTI and Bt insecticidal protein genes, both petal and leaf showed significantly higher insect resistant activity than bud and boll heart.

结果表明：7月中旬两种转基因抗虫棉抗虫效果均较好，尤其是CpTI-Bt棉棉叶和花瓣对4龄幼虫3天内致死率为92%以上；8月中旬两种转基因棉的抗虫活性均明显降低，且Bt棉的杀虫活性显著低于CpTI-Bt棉，其幼虫死亡率与对照受体棉中16的死亡率之间无显著差异，仅显著抑制了幼虫的生长；石远321(SGK321受体品系)的花瓣具有一定的抗虫活性，可显著降低取食幼虫的体重，甚至造成部分幼虫死亡；CpTI-Bt棉中，花瓣和棉叶的抗虫性明显高于蕾和铃心。

Objective: To investigate the changes of follicle-stimulating hormone receptor and luteinizing hormone receptor in ovary of female rat exposed to psychological stress, and the mechanism of ovarian dysfunction.

目的：探讨雌性大鼠心理应激状态下，卵巢促卵泡刺激素受体、黄体生成素受体的变化，进而阐明卵巢内分泌功能失调的机制。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！