受体

The team then looked at autopsied brains from RLS patients for possible differences in histamine receptor location and found that the substantia nigra, the part of the brain implicated in RLS, contained a higher number of histamine-3 receptor proteins, suggesting that this molecular pathway is more active in people with RLS.

研究小组随后看着从解剖大脑的RLS患者可能差异组胺受体的位置和发现，黑质，部分脑牵连的RLS ，包含了较多的组胺- 3受体蛋白，这表明这种分子途径更积极的RLS人。

In the study, RT-PCR and sequencing were employed to detect the expression levels of CCK-B receptor, CCKBRi4sv and gastrin mRNAs in 30 human gastric carcinoma and their corresponding normal tissues, 10 gastritis and 2 autopsied normal stomach specimens as well as in a gastric carcinoma cell line SGC-7901 cells.

本研究首先用RT-PCR及测序方法检测了30例人类胃癌组织及癌周正常胃粘膜、10例胃炎、2例尸检胃组织及胃癌细胞株SGC-7901中CCK-B受体、CCK-B受体的异位剪接变异体(intron 4-contained variant of cholecystokinin B receptor，CCKBRi4sv)及胃泌素基因的表达。

Current understanding of the kinetics of IgE binding to high-affinity receptors on mast cells and basophils is imperfect, but available data suggest that disarming high-affinity receptors on these cells is likely to take weeks rather than hours or days.

目前对IgE与效应细胞表面高亲和力受体结合的动力学状况尚不清楚，但已有的资料表明使这些高亲和力受体失活可能需要几周时间，而不是几个小时或几天。

The mPSCs induced by GABA released from the presynaptic boutons could be completely and reversibly blocked by 5μM bicuculline, which is the specific antagonist of GABAA receptor. These results indicate that GABA released from the presynaptic boutons may produce modulatory effects through binding with GABAA receptor on postsynaptic Vme neurons.

以上结果表明：突触前终扣内释放的GABA与分布于突触后的GABAA受体结合从而发挥对Vme神经元的调控作用，GABAA受体激活后，氯离子通道开放，Vme神经元胞体内外氯离子流动构成了GABA对Vme神经元的作用基础。

The expression of M1 and M4 subtype receptor in the retina, choroids and posterior sclera were detected with immunohistochemistry and the mRNA level of two receptors in the three tissues were examined via RT-PCR.

实验结束后，通过RT－PCR对各组巩膜、脉络膜和视网膜内M1和M4亚型受体的mRNA水平进行检测，同时使用免疫荧光法检测两种受体在各个组织中的表达情况。

Theexpression of M_1 and M_4 subtype receptor in the retina, choroids and posterior sclerawere detected with immunohistochemistry and the mRNA level of two receptors inthe three tissues were examined via RT-PCR.

实验结束后，通过RT—PCR对各组巩膜、脉络膜和视网膜内M_1和M_4亚型受体的mRNA水平进行检测，同时使用免疫荧光法检测两种受体在各个组织中的表达情况。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

2AR knockoutmice and wild-type congenic FVB/N controls were studied, aswell as 2 groups of wild type mice given either ICI 118,551(0.2 mg/kg) or 0.9% saline intraperitoneally 30 min before MCAO( n = 10 per group).

大鼠分为两组，分别为β2-肾上腺素能受体缺乏小鼠及野生型同类系小鼠作为对照组，两组野生型小鼠在 MCAO 30分钟前分别腹腔内随机注射选择性β2-肾上腺素能受体阻滞剂 ICI118，551（0.2mg/kg ）或0.9%生理盐水（每组 n=10）。

Analysis of the relation between serotonin and its receptor in OFC and stress depression(n=8):(1) Microinjection of 5-HT into OFC significantly shortened immobility time, dejections have no great changes; though locomotor、 grooming activitives have little increased, they have no significant difference; rearing scores greatly reduced;(2)microinjection of pCPA into OFC significantly prolong immobility time, dejections have no great changes; locomotor、rearing activities are greatly reduced, but have no significant effect on grooming activity receding;(3)compared with the effect of 5-HT alone, microinjection of spiperone combined with 5-HT into OFC, significantly prolong immobility time and greatly reduced dejections; locomotor、 rearing、 grooming activities are all reduced, but have no significant differences.

眶额叶区5-羟色胺(5-hydroxytryptamine，5-HT)及其受体与应激性抑郁症的关系(n=8)：(1)注射5-HT后，大鼠FST不动时间明显降低(P＜0.05)，粪便数量变化不显著(p＞0.05)，OFT水平运动、修饰得分虽均有升高，但无显著性差异(P＞0.05)，垂直活动显著降低(P＜0.05)；(2)注射色氨酸羟化酶抑制剂-对氯苯丙氨酸后，FST不动时间明显增加(P＜0.01)，粪便数量无显著性变化(p＞0.05)，OFT水平、垂直运动显著减少(P＜0.05)，修饰降低但无显著差异(P＞0.05)；(3)与5-HT组比较，先注射5-HT_(1A)受体拮抗剂后再注射5-HT，FST中的不动时间明显增加(P＜0.01)，粪便数量显著减少(p＜0.01)，但OFT水平、垂直、修饰活动均有所减少，却无显著性差异(P＞0.05)。

During peri-implantation, the decrease of the ECL and the PHA-L receptors may lead to the failure of implantation in the oviduct, and the increase of the UEA receptors at diestrus may contribute to the process of fertilization.

围植入期ECL和PHA-L受体表达下降，在输卵管内形成了不利于植入的微环境，可能是胚泡正常情况下不植入输卵管的原因之一；动情期UEA受体水平显著低于动情间期，有利于受精过程的正常进行。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！