受体

Post mortem studies of suicide victims have shown a diffuse reduction in serotonin receptor transporter sites in the ventromedial PFC, and an increase in postsynaptic 5-HT (1A) receptors in localized regions of the PFC.

自杀死亡的尸检研究发现，腹内侧 PFC 的 5-HT 受体转运体位点普遍减少，并且 PFC 的部分区域突触后 5-HT (1A)受体数增加。

Nearly 70%of X.tropicalis GPCRs are represented by three types of receptors thought to receive chemosensory information from the outside world: olfactory,vomeronasal 1 and vomeronasal 2 receptors.

3不管是从受体的种类还是数量来看，热带爪蟾中的G蛋白偶联受体更趋近于高等动物，兼有水生和陆生特点，表现出从水生到陆生的过渡形态。

In this study, we investigated the effects of O-desmethyltramadol on M1 and M3 receptors, using the Xenopus oocyte expressionsystem.

本研究使用蟾蜍卵母细胞表达系统观察了 O-去甲基曲马多对 M1受体和 M3受体功能的影响。

Disruption of lipid rafts and caveolae by depleting cellular cholesterol with cholesterol-binding reagent,β-methylcyclodextrin or filipin, blocks the IGF-1 receptor signaling in 3T3-L1 preadipocyte.

通过免疫荧光和纯化脂质筏/质膜微囊的方法，发现IGF-1受体定位于脂质筏和质膜微囊中，而且IGF-1受体可以直接和微囊素－1相互作用。

However, fully consideration of special structure and physiological function of CRP is critical to investigate whether CRP provide protect effect or pathogenic effect in the progression of atherosclerosis. CRP is a member of pentrxins family, which consists of five identical, noncovalently associated 23-kDa protomers arranged symmetrically around a central pore with a 102 A external diameter. Each protomer has a recognition face with a phosphocholine binding site consisting of two coordinated calcium ions adjacent to a hydrophobic pocket. The opposite face of the pentamer is the effector face, where complement Clq binds and Fc receptors are presumed to bind. A cleft extends from the center of the protomer to the central pore of the pentamer. Both faces ofpentamer form a special bi-phase structure: one face is the ligand recognition phase, which can recognize apoptosis cells and enzyme modified low density lipoprotein in which PCh is exposed.

CRP是一种五聚体蛋白，外径为102 A，由5个相同的单体以非共价键结合，形成双面的环形结构，每个单体的配体识别位点或受体结合位点分别位于五聚体两个平面上，分别组成配体识别相和效应器相，从而构成特殊的二相性结构：一面为配体识别相，含有磷酸胆碱(phosphorycholine，PCh)结合位点，能够使CRP识别在病理条件下暴露出PCh的凋亡细胞、酶修饰低密度脂蛋白(enzyme modified low density lipoprotein，E-LDL)等。E-LDL是天然低密度脂蛋白(native Low density lipoprotein，N-LDL)在多种蛋白酶，如胰蛋白酶、神经氨酸酶、胆固醇酯酶等作用下的代谢产物，其主要特点是结构发生改变(N-LDL大小均匀，平均直径250±30 A，E-LDL大小差异极大，直径为100-2000 A)，暴露磷酸胆碱位点，能够被CRP识别；另一面为效应器相，能够与巨噬细胞、单核细胞表面受体FcγRⅡa结合，介导巨噬细胞、单核细胞识别及吞噬凋亡、坏死细胞作用。

The isolated aerobic ammonia oxidizers could use nitrite as electron acceptor to carriy out anaerobic ammonia oxidation as well as using oxygen as electron acceptor to oxidise ammonia.

所分离的好氧氨氧化菌能以氧作为电子受体进行亚硝化作用，也能以亚硝酸盐作为电子受体进行ANAMMOX作用。

Firstly, cross donor and recipient lines to produce F1; secondly, repeated backcross the F1 individuals and the subsequent progenies with the recipient to recover its genetic background; and thirdly, intercross the backcrossed progenies to fix the introgressed genes in the population.

在标记辅助导入过程中，标记信息既可用于辅助前景选择，即对目标基因携带者的选择，以保证目标基因的正确导入，也可用于辅助背景选择，即对受体基因组的选择，以加快受体遗传背景的恢复。

The inward currents evoked by ATP was decreased in hypoxia condition,but suramin can still inhibit the depolarizing currents.

免疫组化实验结果显示在大鼠海马CA1区有多种P2X受体亚型的表达，低压缺氧可以引起P2X受体各个亚型表达的上调。

This gene encodes a receptor, the HIV receptor to make use of this invasive called CD4 + T cells in immune cells.

这一基因编码了一个受体，艾滋病毒利用这个受体来侵入称为CD4+ T细胞的免疫细胞。

ABSTRACT It is because that the excellent acceptors for maize transgenic engineering are insufficient in our country, especially in the southwest mountain areas of china and hereditary variation regularity for the two characters such as efficiency of embryonic callus induction and number of regenerating plant (these two characters were abbreviated to the nduction efficiency and number of regenerating in the following of the paper, respectively), which hint the maize culturing capacity, is not very clear. Therefore, aiming at picking out superior acceptors, we had made systematic researches on the two characters with combing traditional quantitative-character genetic analyzing methods such as single-factor genetic mating design, diallel crossing genetic design, genetic effect analyzing method and the modern molecular locating method such as QTLs'. The main results are followed.(1) 50 superior inbred lines and about 30 crosses in our country, especially in the southwest of China were used for identifying and selecting the superior genotypes in the above two investigated characters under the same culturing condition in 2000 and 2001. There was very significant difference among the genotypes in the both characters. But the two characters were not certainly related. Some genotypes such as 18-599 and 18-599 were very good in them. For some ones such as zong 31, induction was higher than 18-599 and 18-599 in the efficiency, but it was only 1/3 to the later in regenerating number. In some genotypes such as S37, R08, R15, P138, A318, induction efficiency was just about 3% and scarcely any regenerating plants were got. On the whole, hybrids acted better than inbreeds in the both characters.(2) Two kind of inbreeds were selected as parents of the Griffing's method 1. 18-599 and 18-599 and the inbred line zong 31 are one kind because they are not only superior in the characters of maize cross breeding, such as CA, resistance to disease and the important agricultural characters, but also excellent in transformation characters as the induction and regeneration.

针对我国、特别是西南山地所需玉米转基因工程育种优良受体极为匮乏和反应玉米幼胚培养能力的2个主要性状，即玉米幼胚胚性愈伤组织诱导率和胚性愈伤组织绿苗发生数的遗传变异规律十分不清楚的实际情况，本研究从筛选玉米转基因工程所需要的优良受体入手，采用单因素遗传交配设计、双列杂交遗传交配设计、世代基因效应等传统数量性状分析方法，以及现代分子标记定位主效QTL分析方法，对玉米幼胚胚性愈伤组织诱导率和胚性愈伤组织绿苗发生数等2个性状进行了较为系统的分析研究，取得以下主要研究结果：(1)于2000年和2001年通过对我国、特别是西南地区近50份优良自交系和近30个杂交组合，在相同培养条件下，对幼胚培养胚性愈伤组织诱导率和胚性愈伤组织绿苗发生数等2个幼胚培养能力性状进行了筛选与鉴定，发现玉米不同基因型具有完全不同的幼胚培养胚性愈伤组织诱导率和胚性愈伤组织绿苗发生数，但幼胚培养胚性愈伤组织诱导率与胚性愈伤组织绿苗发生数并不具有必然的相关关系，有的基因型，如自交系18-599和18-599在胚性愈伤组织诱导率和愈伤组织绿苗发生数等2个性状都表现相当优异；有的基因型，如自交系综31，仅幼胚培养胚性愈伤组织诱导率性状表现高于19-599和18-599，但在胚性愈伤组织绿苗发生数这一性状则与它们有相当大的差距，仅为19-599和18-599的1/3左右；有的基因型，如S37、R08、R15、P138、A318等玉米自交系不仅幼胚培养胚性愈伤组织诱导率很低，平均仅在3％左右，而且胚性愈伤组织绿苗发生数表现也很差，基本上没有分化成苗。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！