受体

We tested whether inhibitory GABAergic synaptic transmission regulates Xenopus optic tectal cell dendritic arbor development in vivo by expressing a peptide corresponding to an intracellular loop ofthe gamma2 subunit of type A GABA receptors GABA(AR, which is required to anchor GABA receptors to the postsynaptic scaffold.

我们想证明如下设想：抑制性GABA能突触传递是否能调节早蟾视顶盖细胞的树突发育。因为GABA受体的gamma2亚基有一段细胞内的跨膜端序列，这段序列对锚定GABAA受体到突触后膜是必须的，所以我们的主要方法是设计了一段特异性的争对细胞内段的序列，这样就特异性的阻断了单个细胞GABA能的突触传递。

Changes in synaptic plasticity in dopamine neurons of the ventral tegmental area may contribute to circuit modification induced by many drugs of abuse, including cocaine.

这种LTP的易化产生是由可卡因诱导衰减GABA受体而产生的。GABA受体可以抑制多巴胺神经元的活动。

I Thio was sensitive to bicuculline, a -aminobutyric acidAreceptor antagonist, but not to strychnine, a glycine receptorantagonist.

I Thio 对γ-氨基丁酸 A 受体拮抗剂荷包牡丹碱敏感，而对甘氨酸受体拮抗剂士的宁不敏感。

Methods: Eleven B-CLL patients were studied. Leukemic lymphocytes with (n=8) or without (n=3) P2z receptors were exposed in vitro to ATP, benzoylbenzoic-ATP, 2-methylthio-ATP(2MeSATP), adenosine-5′-［γ-thio］ triphosphate, and other nucleosides for 8h. Apoptosis was detected by electron microscopy, agarose gel electrophoresis, and quantitative TdT assay. Results:Apoptosis was detected only in leukemic lymphocytes with P2z receptors. By using the quantitative assay, ATP-inducing DNA strand breaks were found to occur specifically for BzATP, ATP and 2MeSATP, but not for ATP-γS and other nucleosides.

将表达P2z受体［P2z］与不含P2z受体［P2z］的两组CLL细胞分别同1.0mmol/L三磷酸腺苷体外培养8小时，以电镜、DNA凝胶电泳和定量DNA 3′端TdT法检测细胞凋亡；并对ATP、苯甲酰苯甲酸ATP、2-甲基硫ATP(2MeSATP)、γ-硫代ATP及其它核苷的诱导效应和氧化型ATP、1-［N，O-二(5-异喹啉碘酰基)N-甲基-L-酪氨酰］-4-苯哌嗪KN-62）的抑制效应做定量研究。

In this double-blind study, 142 women with high-risk singleton pregnancies received 100 mg progesterone or placebo daily by vaginal suppository. Between 24 and 34 weeks of gestation, all subjects had uterine contraction monitoring with an external tocodynamometer once weekly for 60 minutes.

对早产的高危险孕妇来说，预防性地在阴道使用progesterone可降低子宫收缩的频率，并减少早产的发生，虽然目前我们还不清楚它的作用机转为何，但我们知道它对子宫肌肉层有2种作用：一为藉由抑制细胞质内动情素受体的取代而抑制动情素发挥作用，另一个则是经由它自身的细胞性受体而直接作用在子宫的生合成路径上。

As the first attempt, it was designed to reveal the general pattern of lectin receptor distribution on the surface of female cells, namely egg cells, central cells and synergids of Torenia fournieri and, especially, toensure the possible effects of cell isolation procedure on the distribution of lectin receptors by four different systems.

在烟草活体的中央细胞及卵细胞表面发现了伴刀豆凝集素受体的极性分布或者称之为&镶嵌性分布&。在大部分的中央细胞膜表面，该凝集素受体主要分布在靠近核的部位，而在相对侧的荧光要弱或缺失。

Further,with indirect immunohistochemistry technique,CD25(IL-2 receptor or IL-2R) cross-reaction has been identified on lymphocyte membrane of Ctenophaxyngodon idellus and Trionyx sinensis using mouse monoclonal antibody directed against Human Leucocyte Differentiation Antigen CD25(IL-2R).

进一步用抗人白细胞分化抗原CD25(IL-2受体，简称IL-2R)单克隆抗体进行免疫组化交叉反应提示草鱼、中华鳖淋巴细胞膜上含有与人类IL-2R类似功能和结构的物质。关键词：白细胞介素-2；白细胞介素-2受体；发育和比较免疫学；草鱼；中华鳖

Glucocorticoids are effective in inducing apoptosis via the uncharacterized mechanisms in many hematological malignancies. GC-induced apoptosis is initiated by, and strictly dependent upon, the interaction of GC with its receptor, the GR.

糖皮质激素(glucocorticoid，GC)通过与其特异性受体-糖皮质激素受体(glucocorticoid receptor，GR)结合，不仅可诱导未成熟胸腺细胞凋亡，而且对急性白血病细胞、淋巴瘤细胞、骨髓瘤细胞等均有促凋亡作用，诱发凋亡正是应用糖皮质激素治疗白血病的分子生物学基础。

The expression of AT1 and AT2 receptor was examined in ureteric bud cell of the embryonic mouse, including embryonic days 12, 14, 15, 16 by immunohistochemical technique.

采用免疫组织化学方法检测胚龄12，14，15，16 d小鼠肾脏发育早期输尿管芽分支中血管紧张素Ⅱ受体1和受体2的含量。

In peripheral blood,〓increases, so cause 〓 balance is broken, and 〓 which can induce inflammatory reaction increases obviously too; meanwhile, there are immuno- function change in the red cells, the RBC-〓 receptor rosette promoting rate of serum decrease, indicate this uveitic animal model have both cellular immunity dysfunction induced by T cells and the changes of RBC immuno-function. The analysis of the local and systemic immuno-function changes of uveitic animal model offers objective theoretical bases for combining the local treatment and the systemic treatment.

葡萄膜炎兔房水中房水中〓及IL-2均升高，病变葡萄膜组织中T细胞表面分化抗原的免疫组化检查显示大量阳性细胞，表明兔葡萄膜组织本身存在着免疫功能亢进所导致的病理改变，而外周血中〓增高，导致〓平衡失调，介导炎症反应的〓亦明显增高，同时伴有红细胞免疫功能改变，外周血中RBC-〓受体花环率及血清中RBC-〓受体花环促进率均降低，显示葡萄膜炎兔本身既存在T细胞介导的细胞免疫反应功能紊乱，也存在红细胞免疫功能改变，这种局部和全身的免疫功能改变分析为葡萄膜炎的治疗局部和全身相结合提供了客观的理论依据。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！