受体

It was found that an acylguanidine derivative characterized by having a tricyclic structure or a pharmaceutically acceptable salt thereof has a strong antagonism to 5HT2B receptor and 5HT7 receptor.

发现以具有三环类结构为特征的酰基胍衍生物或其制药学上可接受的盐对于5-HT 2B 受体和5-HT 7 受体都具有强力的拮抗作用。

Result:It was showed that Zhechong not only lowered markedly whole blood viscosity,plasmatic viscosity and packed cell volume but also promoted red cell immune function,which may be:①RBC C3b receptor rosette rate(RCR1R) could be enhanced,②RBC immune complexes rosette rate could be reduced,③the serum rosette forming enhancing rate of RBC C3b receptor could be increased,④the serum rosette forming inhibitory rate of RBC C3b receptor could be decreased.Moreover,there were the inverse correlation between blood viscositv and RCR1R.

结果：虫能明显降低瘀血大鼠的全血比粘度、血浆比粘度和红细胞压积；提高瘀血大鼠红细胞C3b受体花环率，使红细胞免疫复合物花环率下降，血清红细胞免疫粘附促进因子活性增强，而抑制因子减弱；血液粘度与红细胞C3b受体花环率的相关分析呈显著负相关。

Immunofluorescence cytochemistry was used to detect the expression of IPSCs fibroblast growth factor receptor 3, the expressions of SV40Tag and fibroblast growth factor receptor 3 in the human precartilaginous stem cells were determined by RT-PCR.

以免疫荧光细胞化学技术检测永生化人前软骨干细胞成纤维生长因子受体3，以RT-PCR检测永生化人前软骨干细胞及人前软骨干细胞中SV40Tag和成纤维生长因子受体3表达。

Neuronalα4β2 nicotinic acetylcholine receptors are the most widespread subtypes in central nervous system.α4β2 nAChRs mainly exist in procerebrum, parietal lobe cortex, temporal lobe cortex, hippocampus, basal ganglion and cerebellum.

神经元烟碱受体α4β2亚型是中枢神经系统分布最为广泛的烟碱受体亚型，占脑内与烟碱有高亲和力的nAChRs的90%，主要分布在前脑、顶叶和颞叶皮质、海马、基底神经节和小脑。

Objective To use an ischemical reperfusion injury rat model by pulsinelli-4-VO andobserve the changes of the expression of Glu, N-methy-D-asparagic acidreceptor subunits NR_1 and NR_(2B) and ability of learning and memory after procerebrum ischemic reperfusion injury, and approach the pathogenesy of learning andmemory disorder induced by ischemic reperfusion injury, and the intervention ofginsenoside Rg_2 on the learning and memory disorder after procerebrumischemic reperfusion injury.

目的利用pulsinelli四血管法体建立脑缺血／再灌注损伤模型，观察前脑缺血损伤后谷氨酸、N-甲基-D-天门冬氨酸受体亚单位NR_1、NR_(2B)表达的变化及学习记忆的改变，从兴奋性氨基酸的兴奋毒作用尤其是其受体的表达方面探讨脑缺血／再灌注损伤引起的学习记忆功能障碍的发生机制，并观察人参皂苷Rg_2对脑缺血缺氧损伤引起的学习记忆障碍的干预机制。

Key words:protein P53;Genes C-erbB-2;Receptors,Estrogen;Receptors,Progestational Hormones;breast neoplasms;Immunohistochemistry

目的：探讨乳腺癌中P53、C-erbB-2基因蛋白及雌激素受体、孕激素受体的表达及其临床病理意义。

Two types of reagents were employed to prove the proteic characteristic of ANS receptor, the result of which demonstrated the proteic characteristic of the toxin.

本试验采用两种试剂，从两个角度表明了ANS受体和质膜上存在的Ⅱ-3受体具有蛋白特性。

A challenge in such a use is expansion and directed seeding in itro, requiring proliferation and surial, and directed migration, respectiely, prior to functional differentiation. The epidermal growth factor receptor is the prototypal growth factor receptor and elicits these responses from a wide ariety of stromal, epithelial, and endothelial cells.

对于这一种细胞的应用所面临的挑战是在功能性分化前在体外的直接种植和扩增、增殖及分化以及导向性迁移等，表皮生长因子受体是一种原型生长因子受体可以在间质细胞、表皮细胞及内皮细胞中引出上述效应。

The SPECT imaging of ~(99)Tc~m-GEBP11 can show the tumor mass clearly and ~(131)I-GEBP11 has anti-tumor effect with weak toxicant and secondary effect, which is the foundation for them to develop nuclide probe or radiotherapeutics drugs targeting to tumor vasculature.3. GEBP11 can inhibit angiogenesis, which comes true probably through its inhibition effects on the proliferation, invasion, migration and adherence of ECs.

1、GEBP11具有活体内胃癌血管靶向结合的能力，它与胃癌血管内皮细胞膜受体特异结合后可被内化。2、~(99)Tc~m-GEBP11 SPECT成像能较好地显示体内肿瘤灶，~(131)I-GEBP11具有明显的抗肿瘤效应及较弱的毒副作用，为开发肿瘤血管成像核素探针及受体放射治疗新药奠定了基础。3、GEBP11具有抑制胃癌血管生成的作用，这可能通过抑制ECs增殖、基质降解及迁移、粘附能力实现。

Effect of regional CTLA4Ig gene transfection on the rejectiveresponsiveness of small bowel recipients in ratsObjective: To evaluate the local expression of CTLA4Ig gene in smallbowels and its action on the rejective responsiveness of small bowelrecipients in rats.

四、移植肠局部C TLA4Ig转基因对受体免疚排斥反应的影响目的：研究CTLA4Ig基因在小肠局部转染表达及其表达产物对受体免疚排斥反应的影响。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！