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It seems that regulation of both glutamate release and NMDA receptor trafficking are worked in the protective effect of carnosine on Aβ42-induced neurotoxicity.

以上结果提示了H_3受体拮抗剂对Aβ42诱导细胞损伤的保护作用可能是通过对胞外谷氨酸含量及NMDA受体膜上表达调节的共同作用而引起的。

In enalapril treated group,there were no changes in AT1,AT2 re ceptor mRNA expression and AngⅡ receptor densities.

SHR+依那普利组AT1、 AT2受体mRNA表达及Ang Ⅱ受体密度均无改变。

We have found that microfilament of cytoplasm was decreased or disappeared and rate of lateral diffusion of ConA r ceptor was increased (D = 1.05 ×10-10cm2/ sec)after the cells were treated with CB. The microfilaments and the rate of lateral diffusion of ConA receptor on cell membrane were recovered D = 0.81 ?

经CB处理细胞后,胞质微丝减少或消失,但是膜ConA受体复合物的侧向扩散运动增加〔D〕=1.05×10~(-1)cm~2/sec,当除去CB后,微丝重新出现,膜ConA受体复合物的侧向扩散运动又减慢〔D〕=0.81×10~(-1)cm~2/sec,与对照组相似。

Expression of epidermal growth factor receptor in breast can- cerin relation to steroid hormone receptors and prognosis. Epider- mal growth factor receptor is a transmemberane protein encoded by the oncogene c-erbB-1. It presents in all types of tumor cells and certain normal tissues, and it is thought to be related to cell carcinogenesis and uncontrolled cell growth.

表皮生长因子受体(Epidermal growth factor receptor,EGFR)是原癌基因c-erbB-1的表达产物,它是一种细胞膜受体,广泛存在于各种类型的肿瘤细胞和某些正常组织细胞中,与细胞癌变和失控性生长趋势有关。

The former stimulates the cells and transfer the signals into the cells through the ligation with receptors on the cell membrane. The latter, a derivative of nucleotide, causes a cytotoxic effect to suppress thymidylate synthetase activity, and, therefore, to damnify RNA and DNA synthesis.

前者通过与细胞表面的受体结合,把胞外刺激传递到胞内,诱导免疫受体介导的信号级联放大作用,引起一系列免疫效应;后者是是小分子的核苷酸衍生物,可直接进入细胞内,通过抑制胸苷酸合成酶及损伤RNA、DNA等对基因转录和核苷酸代谢产生影响,最后产生细胞毒效应。

The remaining 9 rats in control group, 16 rats in treated grouop and 15 rats in model group were decollated and obtained brains to detect the relative mRNA expression of nuclear receptor-related factor 1 (Nurr1) and muscarinic acetylcholine receptor 5(M5) byusing RT-PCR, which was the consequence of those comparing with reference geneβ-actin mRNA expression.

将对照组、治疗组、模型组其余9、16、15只大鼠,断头取脑,采用RT-PCR方法检测大鼠脑组织孤儿核受体及乙酰胆碱毒蕈碱型受体5(M5)mRNA相对于内参基因β-actin mRNA的相对表达值。

Under the conditions of NO3(superscript -), two groups of DPAO existed and dominated in the system (40%~61% of VSS), namely DPAO35 and DPAO5, and they were able to denitrify NO2(superscript -) and NO3(superscript -) or NO3(superscript -) only as respective electron acceptor.

在NO3条件下,系统中存在2类DPAO:DPAO35(以NO2或NO3为电子受体)和DPAO5(以NO3为电子受体);作为系统的优势功能菌,DPAO占总VSS的40%~61%。

The executive system, in contrast, is known to be carried outin the prefrontal cortex and dorsolateral prefrontal cortex,which are central to learning, planning, regulating impulses,and making rational decisions.

这些自动受体通常在它最初释放后&擦掉&自由多巴胺的总量。更少的自动受体意味著这些人在多巴胺引发刺激后,更可能有更&激烈&的行径。

Several factors affecting transformation of elite maize inbred lines were studied, and an efficient and stable transformation system of embryogenic calli was established.

研究了影响玉米基因枪转化受体系统效率的若干因素,建立了玉米优良自交系的稳定、高效胚性愈伤受体系统,获得了正常结实的转基因植株。

In eukaryotic cells,Toll-like receptors in endosomal membrane were show to recognize viral RNA in endosome and thereby initiate innate immunity pathways for virus resistance.By contrast,a cytosolic RNA receptor protein, RIG-Ⅰ(retinoic acid inducible gene-Ⅰ),has recently been identified for recognition of the viral RNA.

在真核生物体内,除了定位于内吞体膜上的TOLL样受体能够识别入侵机体的病毒RNA,启动机体抗病毒的固有免疫反应外,近年来发现了另一种能够识别病毒RNA的细胞质内受体——RIG-Ⅰ。

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