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Methods: Sprague Dawley rats have been used as recipients and Wistar rats as donors. Donor aorta was anastomosed to the recipient's suprarenal abdominal aorta; donor pulmonary artery was anastomosed to the left renal vein of the recipient using continuous suture technique.

以Wistar大鼠为供体,SD大鼠为受体,将供心的主动脉和肺动脉分别与受体肾血管上方的主动脉和左肾静脉用连续缝合技术行端侧吻合。

The results showed: there was not statistic difference of recurrence rate between ER positive and negative groups. There wasn't either statistic difference of recurrence rate between AR positive and negative groups.

结果提示膀胱癌复发率随雌激素受体表达增多有下降趋势,但无统计学显著差异;雄激素受体表达阳性与否亦与肿瘤复发率无关。

Based on the above-mentioned, two kinds of target glycoclusters with different glycoterminus, flexible linkers and different scaffolds were designed, disaccharide glycocluster (including TM1-TM7) and trisaccharide glycocluster (TM8-TM9) respectively, with the purpose of obtaining glycoclusters with high binding affinity to anti-Gal antibody and thus better inhibiting the HAR.

基于上述,针对HAR产生的机制,以人体中天然存在的anti-α-Gal抗体及B细胞表面的相应受体为靶点,以α-Gal抗原末端的二糖Galα1→3Gal和三糖Galα1→3Galβ1-4GluNAc片段为糖基部分,采用柔性的连接臂(氨基保护的2-乙醇胺和3-巯基丙酸)和刚性的芳香骨架及柔性的脂肪链骨架,设计了两类结构新颖的糖簇分子:即氧苷和硫苷键连接的二糖糖簇TM1-TM7)和三糖糖簇(TM8-TM9),目的在于寻找与anti-Gal抗体及B细胞相应受体有较高结合力的糖簇分子,以便有效地抑制HAR反应的发生。

Objective: To investigate the relationship of PPARγ, MMP-2 and MMP-9 with trophoblast invasion.

目的:探讨Ⅱ型核受体的过氧化物酶体增殖物激活型受体γ、金属蛋白酶-2和MMP-9与细胞滋养细胞浸润的关系。

In addition, because these receptors have more binding points, they have better binding properties for anions than the molecular tweezer receptors based on thiourea we reported last time.

与以前我们报道的受体化合物相比,由于此类分子钳受体化合物具有更多的阴离子识别位点,因此具有更好地阴离子识别性能。

So far, the cancerogenic mechanism of lung cancer is not well elucidated. Some growth factors and growth factor receptors have been identified to participate in cancerogenic processes, but the downstream pathways regulated by those growth factor receptors are uncleared.

目前已知的癌症发病机理多是生长因子和生长因子的表面受体发生异常所致,因此,进一步阐明受体下游的调控基因对于阐明癌症的发生机理和进一步设计药物靶位点都是十分有意义的。forkhead box P4(FoxP4)就是本文作者在利用生物信息学方法筛选人类心脏发育候选基因的过程中发现的一个人类新基因,目前发现三种转录本。

objective to investigate the expression of tlr9 and tlr7 mrna of peripheral blood mononuclear cells in patients with uveitis.

目的 观察葡萄膜炎患者外周血单个核细胞toll样受体9(tlr9)、toll样受体7(tlr7)mrna的表达。

Objective To investigate regulative effect of estradiol valerate on the expressions of estrogen receptor-alpha and -beta in the vagina of rats after ovariectomy. Methods A total of 80 adult female SD rats weighing about 340 g were randomly and equally allocated into 4 groups: normal control group, sham operation group, ovariectomized group and drug group.

目的 通过研究戊酸雌二醇对去势大鼠阴道雌激素受体(estrogen receptor, ER)亚型α、β表达的调节,探讨雌激素受体亚型与绝经期泌尿生殖道萎缩的相关性。

This was followed by invitro studies of receptor-dependent and receptor-independentpulmonary vasoconstriction using an isolated perfused lung model.

随后在离体肺灌流模型中研究受体依赖性及非受体依赖性肺血管收缩。

Because windup partly depends on the N-methyl-d-aspartate receptor, action at this receptor is not critical to immobility produced by these anesthetics.

因为windup部分依赖于NMDA受体,此受体的活动在这些麻醉药产生的制动作用中并不关键。

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