受体

(1) The difference between alcohol dependence and control group at 5-HT1B receptor gene G861C was not significant in Jinuo population of Yunnan province.

（1）5-HT1B受体基因G861C多态分布在云南省基诺族酒依赖人群和正常对照中无差异性，5-HT1B受体基因G861C多态性与基诺族酒依赖的发生无相关性。

To study the regulatory effect of two different tonifying kidney (Fructus Ligustri Lucidi and Epimedium) on mRNA and protein expression of estrogen receptor βin male rat amygdaloid nucleus and cortex regions.

目的 通过检测服用补肾阳中药和补肾阴中药后的雄性大鼠杏仁核和皮质顶叶雌激素受体mRNA及蛋白，从分子水平探讨补肾中药对雄性大鼠神经系统雌激素受体的影响。

Both NMDA and non-NMDA receptors are involved in transmission andor modulation of spinal visceral nociceptive information and non-NMDA receptors may play more important role than NMDA receptors.

NMDA和非NMDA受体均参与介导脊髓内脏伤害性信息传递，而非NMDA受体的作用更强。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

The idea of synthesis of anion receptor is alsoa base of the design of receptor for neutral molecule.

同时这种阴离子受体的设计理念进一步为中性分子受体的设计提供基础。

A new series of short range donor acceptor systems consisting of anthracene and different substituted benzoic esters were synthesized.

设计合成了一类以蒽为电子给体，带不同吸电子取代基的苯为电子受体的新型短程有机电子给体受体体系。

The effects, of protection and treatment with, combined Ch, NaF and a trophie were significantly better than that with atropine alone. In isolated phrenic nerve-diaphragm preparation of rat, isolated jejuneal preparation of, guinea pig, and the metabolic experiment of rat liver, the results of the, assay on the rat blood ChE activity indicated that antidotal effect of NaF may be due to the antidese...

大鼠离体膈神经膈肌、豚鼠离体空肠和大鼠肝脏代谢实验及对大鼠全血胆碱酯酶活力测定的结果表明，NaF的抗毒作用可能是由于其对神经肌肉接头和/或神经节中的N受体的抗脱敏作用；而Ch则可能通过其对ChE的保护和/或加速被抑制ChE的复能，阻碍Ach到达M受体部位而发挥作用。

Objectives To investigate the functions of dopamine D: and D2 receptor in form deprivation myopia and the influcnce of apomorphine on inhibition of FDM in chick with rafiligand bgading assay.

目的 采用放射受体分析方法测定鸡视网膜多巴胺受体的理化特性，研究多巴胺系统与剥夺性近视和药物治疗近视相关的机理。

The results show that firstly, ApoE and LDL receptors can be transported bidirectionally (i.e. retro-and anterogr-adely) in the axoplasm along axons. Secondly, ApoE derived from regenerating fillers can be transported re t rogradely to the cell bodies.

本文用免疫细胞化学法研究正常和再生的大白鼠外周神经中脱辅基脂蛋白E和低密度脂蛋白受体的运输特性，发现在正常的外周神经中，ApoE及LDL受体在轴浆中均可沿轴突正行和逆行运输；再生的神经可产生ApoE，ApoE可逆行向细胞体转运。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。