受体

Using whole-cell patch clamp recording, we observed multiple distinct ATPinduced currents in isolated DRG neurons of adult rats, each with unique desensitizing kinetics.β,γ-meATP, agonist of P2X1 receptor also induced fast inactivating and slowly desensitization current in small DRG neurons. PDBu, a selective agonist for PKC, decreased the P2X receptor-mediated inward currents in a dose-dependent manner, while SNP, nitric oxide donor, potentiated the ATP-evoked current through NO-cGMP pathway.

全细胞膜片钳记录观察到，在成年鼠离体DRG伤害性感受相关的小直径神经元上，ATP可诱导出多种具不同反应型式及脱敏动力学的由P2X受体介导的内向流；P2X1受体激动剂β，γ-meATP亦可诱导出快脱敏及慢脱敏两种型式的内向流；PKC激动剂可剂量依赖地削弱P2X受体介导的内向流，而NO供体硝普钠可通过NO-cGMP通途显著易化ATP介导的内向流。

Bidentis were studied by adopting indoor bioassay. The results showed that the volatile matter of F. bidentis had not allelopathy to four receptor plants. The eluviated matter inhibited seedling growth of cotton obviously, the inhibition ratio of root and stem were 6.29% and 10.42% respectively. The aqueous extract of litterfall and root exudates had different inhibition to four receptor plants, The synthesis effectof all treatments was significantly greater than eluviated matter treatment except for B3 of the aqueous extract of root exudates, such as the synthesis effect of all treatments (A1, A2, A3, B1, B2, B3 and eluviation) were 44.74, 29.37, 14.5, 31.54, 16.52, 3.55, 1.48 respectively.

结果显示：黄顶菊自然挥发物对受体植物不表现化感作用；黄顶菊淋溶物对棉花幼苗生长表现出明显的抑制作用，对棉花幼苗高度和根长的抑制率分别为6.29%和10.42%；黄顶菊枯落物浸提液和根系分泌物浸提液对4种受体植物均表现出不同程度的抑制作用，除了黄顶菊根系分泌物浸提液 B3处理外，其它处理的综合效应均显著大于淋溶物处理，如黄顶菊枯落物浸提液（ A1、 A2、 A3）、根系分泌物浸提液（ B1、 B2、 B3）以及淋溶物等各处理对受体植物的综合效应分别为44.74、29.37、14.5、31.54、16.52、3.55、1.48。

Although PRMT1 methylates nuclear orphan receptor HNF4,whether TR3,another orphan receptor,is methylated by PRMT1 and how the methyltransferase activity of PRMT1 is affected by nuclear receptor remain largely unknown.

虽然PRMT1可以甲基化核受体HNF4，但孤儿受体TR3能否发生甲基化以及PRMT1的甲基化酶活性是否被核受体调控等问题还不清楚。

Recent years with the development of molecular biology 14 kinds of 5-HT receptor subtypes have been cloned, which can be subdivided into seven subfamilies.

除5-HT_3受体亚型为配体门控离子通道受体外，其它5-HT受体均为具有七次跨膜结构的G蛋白耦联受体。

There was no difference about the maximum binding,affinity constant and concentration of the insulin receptor in cerebral cell membrane among the three groups.

三组大鼠比较，脑细胞膜的胰岛素受体最大专一性结合、受体亲和力常数及受体浓度均无显著性差异。

Objective To study the effect of Borna disease virus infection on the transcription of monoaminergic receptor genes in the brain tissues of neonatally inoculated rats.

目的分析博尔纳病病毒感染对新生大鼠脑内单胺类受体基因转录的影响。方法选择病毒滴度为2·0×106FFU/ml的BDV病毒液对新生大鼠进行颅内接种，接种量为10μl/只新生大鼠。30d后用RT-PCR和间接免疫荧光方法确定BDV感染情况；并采用半定量RT-PCR方法检测BDV感染大鼠脑组织中多巴胺2(D2)受体和5-羟色胺2α(5-HT2α)受体基因的mRNA转录情况。

The immunoglobulin like anti AChR antibody without complement binding activity is successfully made from a pathogenic anti AChR antibody IgG 637 by site directed mutagenesis.Key words:receptor, cholinergic;myasthenia gravis;point mutation;complement-binding;antibodies

本研究利用定点突变技术，从完型抗乙酰胆碱受体抗体IgG 637制备了不能激活补体的突变型抗乙酰胆碱受体抗体IgG 637/K 322 A，为最终制备出可用于治疗重症肌无力的无补体激活功能的单价抗乙酰胆碱受体抗体提供依据。

Some stimulators, including viruses, tumor cells and hot shock, could promote the expression of NKG2 receptors and their ligands via activating certain transcription factors which are capable of up-regulating NKG2 promoters' activity. Meanwhile, epigenetic mechanisms including DNA methylation and histone posttranslational modifications are also critical to expression of NKG2 receptors and their ligands and may control the clonally distribution of some NK cell receptors.

病毒、肿瘤和热休克等刺激可以通过激活相应的转录调节因子，提高启动子活性而上调NKG2家族受体及其配体的表达，而启动子区DNA的甲基化状态、组蛋白的乙酰化和甲基化等表观遗传调控，在NK细胞受体及其配体的表达方面亦起重要作用，并决定NK细胞受体的克隆性分布。

Glutamate receptors can be divided into two major classes: AMPA and NMDA receptors.

谷氨酸受体主要可以分为两大类：AMPA受体和NMDA受体。

But what the role of PLC-γ 1 in growth factor Hduced cells mitogenic signal transduction is not clear.

当受体与其配体结合并被激活后，PLC-γ1则与激活的受体偶朕，继而在这些受体酪氨酸激酶的催化下，其酪氨酸残基被磷酸化。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。