取代剂

Biaryl substituted pyrazole compounds are sodium channel blockers useful for the treatment of pain and other conditions.

联芳基取代吡唑化合物为钠通道阻滞剂，用于治疗疼痛和其它病症。

The polyaniline hybrid materials doped with cobalt substituted silicotungstate isomers α,β-Kβ(subscript 6-n)H[SiW11Co(H2O)O39]xH2O β(subscript i=β1,β2,β3 have been prepared.

以Keggin结构钴取代杂多硅钨酸盐异构体α，β-K(下标 6-n)H[SiW11Co(H2O)O39]xH2Oβ(下标 i=β1，β2，β3为掺杂剂，采用固相合成法制备了4种聚苯胺掺杂材料。

The paper discusses the preparation of stearic bicine diester for sizing agent and its application in paper-making.

论述了双硬脂酰取代甘氨酸酯施胶剂的制备及其在造纸中的应用。

Whereafter,we achieved a highly enantioselective approach towards the synthesis ofβ-substituted chiral ketones utilizing Oppolzer\'s sultam as chiral auxiliary.The-and-enantiomer of target chiral ketones were obtained with up to 99%ee.

应用手性辅剂樟脑磺内酰胺的手性诱导作用，高对映选择性地合成了一系列β-芳基取代手性酮，其ee值高达99%，可用于药物及其它精细化工中间体的不对称合成。3。

Using the cationic detergent benzyldimethyl -alkylammonium chloride instead of cytochrome C in spreading procedure, we have observed the binding site for EcoR Ⅰ on linear pBR322 DNA molecule in the presence of gluteraldehyde. The diameter of the bound EcoR Ⅰ molecules are 15nm which may be the tetrameric EcoR Ⅰ particles.

用低分子量阳离子去垢剂苯二甲基苄基氯化胺取代经典展层技术中的细胞色素C，汲取前人经验，建立了无蛋白展层技术，适用于蛋白质--DNA相互作用的电镜研究。

Part II The experiment study on anti-tumour effect of dendritic cells derived from peripheral blood monocyte of patients with oral cancer after pulsed by tumour antigen in different ways. Collected 50ml peripheral blood from each patients and volunteers to induced DC in vitro. We parted the test group and control group into three subgroups respectively, untreated group A, freezed and thawn group B, RNA transfected group C. To group A, after induced DCs for five days , we added 200U/mlTNF-α in each hole and cultured on. To group B, we added protein antigen (DC/ tumor cells = 1 : 1 ,each hole) for 4h at 5d, and then added 200U/mlTNF-α in each hole and cultured on. To group C, transfected immature DC with tumor cell RNA(DC:RNA=1×105/ml: 5ug)at 5d, operated completely with the specification of invitrogen DMRIE-C reagents. After transfection we replaced transfection agent with complete medium, and then added 200U/mlTNF-α in each hole and cultured on.

第二部分口腔癌患者外周血来源的树突状细胞体外负载抗原后抑瘤作用的实验研究无菌采集20例口腔癌患者和20例健康志愿者外周血50ml，分离单个核细胞体外诱导培养DC，并将实验组和对照组细胞各分为三组，A组为未处理组，B组为冻融组，C组为RNA转染组。A组DC在培养5d后，每孔加入TNF-α200U/ml；B组DC培养第5d后，每孔中加入癌细胞蛋白抗原，使DC/肿瘤细胞=1：1，继续培养4h后，每孔加入TNF-α200U/ml；C组将培养至第5d的未成熟DC用肿瘤细胞RNA进行转染(DC：RNA=1×105/ml： 5ug，按照invitrogen DMRIE-C试剂说明书进行操作)，转染结束后用完全培基取代转染剂，每孔加入TNF-α200U/ml。

Chlorine atoms were selectively introduced into the chlorin ring based on different reactivity between vinyl group at 3-position and 20-meso position by electrophilic addition and electrophilic substitution using hydrogen peroxide/hydrochloric acid, N-chlorosuccinimide, hydrogen chloride (or concentrated hydrochloric acid) as chlorinating reagent.

以过氧化氢/盐酸、N-氯代丁二酰亚胺、氯化氢为氯化剂，根据3-乙烯基和20-meso-位的不同化学反应活性，通过亲电加成和亲电取代反应，在二氢卟吩环上选择性地引进氯原子，完成8种未见报道的具有叶绿素-a基本碳架的氯代二氢卟吩衍生物的合成。

In view of the improvement on environmental protection and the reduction of costs for PCB fabrication, emphasis has been placed on the use of corrosion inhibitors as replacements for conventional tin -lead electrodeposits for the preservation of solderability.

鉴于电路板生产过程中环保和成本的要求，采用唑类缓蚀剂取代传统的锡铅合金镀层以保证可焊性。

Acetylated starches with high degree of substitution were synthesized from cornstarch with acetic anhydride as esterifying agent and methanesulphonic acid as catalyst.

以玉米淀粉为原料，醋酸酐为酯化剂，甲烷磺酸为催化剂，制备高取代度淀粉醋酸酯。

Preparation of starch succinate with low substitution degree was studied by using corn starch as raw material,succinic anhydride as esterifying reagent,water as solvent and sodium hydroxide as catalyst.

以玉米淀粉为原料，丁二酸酐为酯化剂，以水为媒介，氢氧化钠为催化剂对低取代度淀粉丁二酸酯的制备工艺进行了研究。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。