取代

METHOD Dofetilide was synthesized by steps of reaction (substitution ,reduction, methylsulfonylation and methylammoniation, etc) from p-nitrophenol and p-amino phenethyl alcohol.

以对硝基苯酚为起始原料，经取代、还原、甲磺酰化等反应制得 4甲磺酰苯胺(5 )；以对氨基苯乙醇为起始原料，经甲磺酰化、甲氨化等反应制得 4 甲磺酰苯胺(8)，再与5经取代反应制得多非利特。

Tetra-O-benzyl-D-glucose reacted with bromine to give glucosylbromide. It reacted with hydroxyl phenyl acetonitrile or hydroxyl benzaldehyde to give substituted ph- enylacetonitrile or substituted benzaldehyde.11 New stilbenes were synthesized possessing 2,3,4,6-tetra-O-benzyl-D-glucoside by condensation reaction with pheny lacetonitrile or benzaldehyde, which had potential biological activity and would be sieved in the future.

由2，3，4，6-四芐氧基葡萄糖作为中间体，首先制备出的溴代糖和含有羟基的苯甲醛和苯乙反应制备出含有糖的取代苯甲醛和取代苯乙，再和简单的苯乙或苯甲醛缩合反应生成11种具有潜在的生物活性且含有2，3，4，6-四芐氧基葡萄糖的类化合物，这些新化合物有待于进一步进行药理活性筛选。

The 7-bromo group was replaced with various aniline, and then treated with 4-methoxybenzenesulfonyl chloride to afford the 6-azaindole-1-sulfonamides.The synthesis of 7-aryl-6- azaindole-1- sulfonamide derivatives were prepared by a Suzuki reaction at 7-position, utilizing the 7-bromo-6-azaindole was treated with a variety of phenylboric acid to give the designed 7-aryl substituted 6-azaindoles.

将七号位碳上的溴基取代成各种苯胺类衍生物，再与4-甲氧基-磺基氯苯反应得到6-氮基吲哚-1-磺胺。7-苯基-6-氮基吲哚-1-磺胺类衍生物的合成是以7-溴基-6氮基吲哚-1-磺胺为起始物和各种苯硼酸经由铃木偶合反应在第七号位碳上，得到在第七号位碳上有苯基取代的6-氮基吲哚-1-磺胺。

Four new compounds,substituted-benzyloxyindole-3-formaldehyde-(4′-nitro) phenylhydrazone ,were synthesized by the condensation of 4-nitrophenylhydrazine with substituted-benzyloxyindole-3-formaldehyde in ethanol.

以取代苄氧基吲哚-3-甲醛和4-硝基苯肼为原料，乙醇为溶剂，通过缩合脱水反应合成了4个新化合物——取代苄氧基吲哚-3-甲醛-(4′-硝基)苯腙，其结构经1H NMR，IR，MS和元素分析表征。

On the basis of ascertaining that phosphomolybdic acid modified platinum electrode has higher catalytic activity to methanol oxidation , three kinds of transition metal substituted phosphomolybdic acids were synthesized, and the IR spectrum indicated that the compounds still kept Keggin structure.

在证实了磷钼酸修饰铂电极对甲醇氧化具有较高活性的基础上，合成了3种过渡金属取代的磷钼酸，通过红外光谱测试仍为Keggin结构，并制备了过渡金属取代磷钼酸修饰铂电极，研究了修饰铂电极在硫酸溶液中的电化学行为及对甲醇的催化氧化作用。

In order to improve the electrocatalytic activity of the anode in the Direct Methanol Feul Cell, three kinds of transition metal substituted phosphomolybdic acid modified platinum electrodes were prepared, and the electrochemical behavior in the sulphuric acid solution of transition metal substituted phosphomolybdic acid modified platinum electrodes and their electrocatalytic effects of methanol oxidation were studyed. The anti-poison effect to carbon monoxide of the prepared electrodes were studied by the carbon monoxide adsorbing.

为了提高直接甲醇燃料电池阳极催化活性，本文研究了三种过渡金属取代磷钼酸修饰铂电极在硫酸溶液中的电化学行为及对甲醇的电催化氧化作用，并利用一氧化碳吸附实验评价了三种过渡金属取代磷钼酸修饰铂电极的抗一氧化碳毒化性能。

The results show that the three kinds of heteropolyacid modified platinum electrodes have the higher electrocatalytic activity to methanol oxidation, PMnMo11 modified platinum electrode has the highest electrocatalytic activity. Meanwhile the anti-poison effect to carbon monoxide of platinum electrode can been improved by modification of transition metal substituted phosphomolybdic acid.

结果表明，三种过渡金属取代磷钼酸修饰铂电极均能够提高铂电极的催化活性，其中PMnMo11修饰铂电极对甲醇的催化活性最高，同时铂电极经三种过渡金属取代磷钼酸修饰后抗一氧化碳毒化能力增强。

The toxicity of selected compounds and their binary mixtures of sodium dodecyl sulfate with three substituted aromatic compounds to photobacterium phosphoreum was investigated, respectively.

研究阴离子表面活性剂十二烷基硫酸钠和苯酚、硝基苯、甲苯3种取代芳烃对发光菌的单一毒性，以及在等浓度配比条件下，SDS与这3种取代芳烃二元混合体系的联合毒性效应，并采用毒性单位、相加指数、相似性参数和泥合毒性指数进行毒性评价。

A series of novel polys: poly, poly and their copolymer poly were synthesized at high temperature by nucleophilic polycondensation of bisphenol 4 (3 phenyl 4 hydroxyphenyl) 2,3 phthalazin 1 one with activated difluorodiphenylketone, dichlorodiphenylsulfone and both together.

将苯基取代类双酚化合物 4-(3 -苯基-4-羟基苯基)-2 ，3 -二氮杂萘-1 -酮与活性双卤单体如 4，4 -二氟二苯酮、4，4 -二氯二苯砜进行高温缩聚反应，合成了高分子量的新型苯基取代杂萘联苯型聚芳醚材料；用1 H NMR、FT-IR表征了类双酚单体及聚合物的结构。

Microsoft has been trying to get developers to move away from INI files for quite some time, pithily suggesting using the Registry instead... despite the fact that it's rarely a suitable replacement.

Microsoft 一定会让开发人员在某个时候不能使用INI文件，建议使用注册表取代，虽然现在还不有一个合适的取代产品。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。