发育异常

There is a cognitive disorder in 85.7 percent of microcephaly children with atelencephalia that is influenced by multifarious factors.

结果 42例患儿发育商值异常者占85.7%（36/42），影响早期认知功能的因素主要包括患儿有异常头颅影像学改变、性别、初诊年龄。

Calidonian granites are widely developed in the Yema Nanshan area in the western segment of the Qilian orogenic belt. The geochemical characteristics of most of the granites are similar to those of adakites: SiO2≥56%, Al2O3≥15.0%, low MgO (average 2.04%), high Sr (257-889μg/g, average 546.42μg/g), low Y (7.1-25.3μg/g,average 16.67μg/g), average Sr/Y=5.89, no pronounced Eu anomaly and Sr positive anomaly. Adakites in this area have five rock types, quartz diorite, quartz monzodiorite, quartz monzonite, monzogrannite and hornblende granite. These rocks commonly contain hornblende, belonging to I-type granites.

提要：祁连西段野马南山一带发育大量的加里东期花岗岩，其中大部分花岗岩具有与adakite岩相似的地球化学特征，SiO2≥56%， Al2O3≥15.0％，低MgO（平均2.04％），高Sr(257～889μg/g，平均值546.42μg/g)，低Y（7.1～25.3μg/g，平均16.67μg/g），Sr/Y平均为35.89μg/g，Eu无明显负异常，Sr正异常，Adakite岩石类型有石英闪长岩、石英二长闪长岩、石英二长岩、角闪花岗岩、二长花岗岩，岩石中普遍含有角闪石，属I型花岗岩，地球化学图解反映该花岗岩形成环境为板块碰撞前的岛弧型，锆石U-Pb同位素年龄为444+38/-33 Ma，处在祁连造山带板块俯冲收缩阶段，因此可以推断野马南山埃达克质Adakite花岗岩是俯冲板片部分融熔和壳幔岩浆混合形成的。

For example, in McCune-Albright syndrome, there are patchy dysplastic changes in the bone, abnormalities of endocrine glands, patchy pigmentary changes, and occasionally abnormalities in the heart or liver.

例如在McCune-Albright综合征中，骨中有发育不良斑块，还有内分泌腺异常，色素斑以及偶有心或肝的异常。

For example, in McCune-Albright syndrome, there are patchy dy lastic changes in the bone, a ormalities of endocrine glands, patchy pigmentary changes, and occasionally a ormalities in the heart or liver.

例如在McCune-Albright综合征中，骨中有发育不良斑块，还有内分泌腺异常，色素斑以及偶有心或肝的异常。

Result: in three categories and ten examples of congenital malformation fetus, the morphological and histological structures of colon in syndactyly and sxtrodactyly fetus have no obvious abnormity; the colon's structure shows abnormity in omphalo-thoracopagus twins; the colon's structure was insufficient development in anencephaly fetus.

结果：三类10例先天性畸形胎儿中，并缺指畸形胎儿结肠的形态学及组织学结构无明显异常；胸腹联体胎儿结肠结构异常；无脑儿结肠组织结构发育不全。

Microcephaly, occipital meningocele, dysplastic ears, optic atrophy, vertebral abnormalities, limb problems including radiohumeral synostosis, subluxation of one hip, joint contractures, and focal femoral hypoplasia.

小头畸形，枕部脑脊髓膜膨出，耳发育不良，视神经萎缩，脊椎异常，四肢问题包括：桡肱骨结合、一侧髋关节脱位、关节挛缩和灶性股骨发育不良。

It is deduced that the abnormal development of tapetum and the abnormal distribution of Ca(superscript 2+) are related to the pollen abortion.

推测绒毡层细胞结构发育的异常和Ca(上标 2+)的异常分布可能与花粉的败育有关。

The results showed that the cell wall organization during anther development failed to divide into inner-wall, middle and tapetum normally, and not to provide material, energy and information transfer for the development of pollen mother cells, resulting in the occurrence of abnormal pollen mother cells separatist period; thus which could not form a normal pollen grains which led to abortion.

结果表明，不育花药壁组织在发育过程中，没有分化形成正常的内壁、中层及绒毡层，不能为花粉母细胞的发育提供物质、能量和信息的传递，造成花粉母细胞在减数分裂期发生异常，不能形成正常的四分体，因而未能形成正常的花粉粒而导致败育。

Chromosomal abnormalities were identified in two anencephalic fetuses. One was trisomy 21, another was mosaic of diploid and tetraploid.

1。组织病理学和超微病理发现，NTDs胎儿在脑和脊髓以及重要脏器如肝、肾等发育有异常，主要表现在发育滞后和某些成分的缺如。

The development of Peiai 64S and IR36 did not differ up to microsporocyte formation stage; but since meiosis stage, male reproductive cells of Peiai 64S underwent several structural changes and ultimately terminated by early bicellular stage.

结果表明，小孢子母细胞减数分裂之前，培矮64S与IR36的发育过程基本相似。但从减数分裂开始，培矮64S的雄性性细胞出现一些异常变化，并最终发育至二胞花粉早期败育。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。