发病的

Meanwhile the function of antioxidant defense system increased to enhance the ability for clearing free radical and antagonized the damage to organism from free radical. So the activity of GSH-Px and T-AOC enhanced. But the compensative ability was limited and the activity of GSH-Px decreased abruptly and the T-AOC was not increased further in cerebellum of chicken with encephalomalacia. This showed that it existed the exhaustion of GSH-Px in cerebellum of chicken with encephalomalacia.

在体内自由基蓄积的同时，机体抗氧化系统功能出现代偿性增强，提高自由基的清除能力，以对抗自由基对机体的损伤，表现为GSH-Px活性和T-AOC的增强，但机体的代偿能力是有限的，发病雏鸡小脑中GSH-Px活性的突然降低和T-AOC的不再增高，表明GSH-Px在发病雏鸡小脑中存在耗竭现象。

In addition, we presume that the role of different MMPs is distinct in various stages of EMs development. The difference of subjects which is resulted by the genetic difference of MMP-1 has the association with the risk of EMs, and the abnormal expression of protein may have relation with the development of EMs; The abnormal expression of MMP-3 has a very important role in the development of EMs; As a protein of endothelial expression, MMP-7 may participate in the development of EMs, endometrial cells with high-expression MMP-7 easily take place ectopic implantation in the blood of menstruate countercurrented and increase the risk of EMs; It is not confirmed in our study that there are the association of MMP-9 with the risk of EMs, but in view of other study, we will further evaluate the role of MMP-9 in the development of EMs.

且推测不同的MMPs基因在子宫内膜异位症发生和发展的不同阶段作用不同，MMP-1基因的遗传差异所导致的个体差异与子宫内膜异位症发病风险的个体差异相关，其蛋白的异常表达还可能与子宫内膜异位症的进展相关；MMP-3基因的异常表达在子宫内膜异位症的发展中起重要作用；MMP-7作为一个上皮性表达的蛋白，可能对子宫内膜异位症的发生起重要作用，带有MMP-7高表达的在位子宫内膜细胞更易在经血逆流中"异位"种植，增加个体子宫内膜异位症的发病风险；MMP-9虽然在本研究中没有被证实与子宫内膜异位症的发生和发展有相关性，但鉴于其它相关研究，有待于从其它方法证实MMP-9在子宫内膜异位症进展中的作用。

The results showed:among the 7 isolates, five isolates of HY3、GY1－3、ZJ1－1、HP1、FC3 had same colony shape, irregular shape, liquidlike, slimy, opacity with smooth surface;the other two isolates had same shape, irregular shape, dry, opacity with coarse surface. By inoculating eucalyptus with the 7 isolates, the plants were infected apparently, and the young plants of eucalyptus in control experiment with tap water were not infected. By cultivating eucalyptus cuttings with the bacterial suspensions without EPS, the incidence of disease was very distinct,but compared with the former bacteria suspension,the incidence of disease has decreased at different degrees. By screening out two isolates of strong pathogenicity and two isolates of weak pathogenicity from the 7 isolates,making the bacterial suspensions with them to inoculate the young plants of eucalyptus, two treatments of cutlings and ramets with rats were set with 5 repetitions in every treatment, the results of data analysis showed: for the cutlings, the bacterial contents in upper and middle parts、upper and lower had significant difference;for ramets with roots, the bacterial contents in upper, middle parts, lower had significant difference between each other; For both the cutlings and ramets with roof, the bacterial contents in xylem and phloem had significant difference. The interaction between vertical and horizontal parts for the bacterial content had significant difference. For the two isolates of HY3 and 93B which were screened out at last,their activities of the cellulase were: 1.955ug/ and 1.288ug/ respectively, and had significant difference; the activities of pectase were: 1.325 ug/and 1.24ug/ respectively, and had no significant difference. The content of EPS extracted from the two isolates of HY3 and 93B was very different: 7.08x10-8ug/cell and 5.17x10-8ug/cell.

结果显示：7个菌株中，其中5个菌株HY3、GY1－3、ZJ1－1、HP1、FC3的菌落形态相同：不规则形状、流体、粘性、不透明、表面光滑；另外2个菌株93B、GN1菌落形态相同：不规则形状、干燥、不透明、表面粗糙；用7个菌株接种剪根桉树苗，发病情况非常明显，而自来水对照实验中桉树苗却不发病；无EPS菌悬液培养桉树剪根苗，发病率也很明显，但是相比原菌液，则发病率有不同程度的下降；从7个菌株中间筛选出来2个强致病性菌株和2个弱致病性菌株，用它们配制菌悬液培养桉树苗，设置剪根和不剪根两个处理，每个处理设置五个重复，数据分析结果显示：对于剪根苗，上部和中部、上部和下部的含菌量有显著的差异，中部和下部含菌量差异不显著；带根苗，上部、中部、下部含菌量彼此之间差异显著；不管是剪根苗还是带根苗，木质部和韧皮部含菌量之间的差异都非常显著；上中下与木韧交互作用中，含菌量差异非常显著；最后筛选出来的强弱2个菌株HY3和93B，它们的纤维素酶活性分别为：1.955ug/和1.288ug/，具有显著的差别；果胶酶的活性分别为：1.325 ug/和1.24ug/，没有显著的差别，而且HY3和93B两个菌株细胞分泌的胞外多糖的含量差异很显著，分别为：7.08×10-8ug/cell和5.17×10-8ug/cell。

Positive significant correlation between three infection indexes and SDD, and negative insignificant correlation between infection indexes and LIP were found. Fifteen sugarcane varieties could be divided into 6 groups on the basis of the distance more than 1.0. It resulted most ot tested sugarcane varieties had similar smut resistance. It suggested that smut race 1 and race 2 were included in inocula and the condition for Ustilago scitaminea infection was suitable in the crop season by setting up the standard varieties of NCo310, F134, NCo376 and Ya71-374 for smut identification. In addition, the results of sugarcane varieties resistant to smut race 1 and race2 were known by only a simple field trial.

结果显示：9个引进甘蔗品种中，ROC26属于感病品种，其余属于抗病或高抗品种；3个病情指数和持续发病期的两两相关均为显著正相关，潜伏侵染期与这些参数的相关为负相关，但未达到显著水平；在类间距离大于1.0的条件下，可将15个品种聚为6类，进一步明确了各品种抗黑穗病性的相似程度；抗性鉴定标准对照种NCo310、F134、NCo376和Ya71-374的应用，明确了接种源为小种1和小种2，通过一次接种试验，明确了供试品种对2个小种的抗性水平，标准对照种的抗性表现，还说明了本生长季发病条件基本是适宜的。

Four field strains of infectious bronchitis viruswere isolated from chicken kidney, trachea and lung of the young layer flocks in some regions of Shaanxi province. Biological characterizations of the virus were investigated by virus pathogenicity to chicken embryo and healthy chickens, hemagglutination test, hemagglutination inhibition test, dwarfing embryonated chicken eggs, electron microscopy and reverse transcription polymerase chain reaction. It demonstrated that allantoic fluid of each passage virus could hemagglutinate chicken red blood cells by treatment with 1% trypsin. The standard positive serum to IBV could inhibited the hemagglutination. The isolates could make respiratory and kidney diseases in chickens.

采集陕西省宝鸡市、扶风县、兴平市和榆林市等地鸡场疑似传染性支气管炎发病鸡病料，通过9～11 日龄非免疫鸡胚进行了病毒的实验室分离和传代，并对分离毒株进行了病毒的血凝性、血凝抑制性、致病性、鸡胚矮小化、电镜特征等生物学特性鉴定，结果表明，4 株分离株经1%胰酶处理后的各代病毒尿囊液均可凝集鸡红细胞，标准阳性血清可特异性的抑制其凝集性，回归试验可复制出与自然发病相同的病例，病毒传代物有明显的致鸡胚矮小化作用，透射电镜下可见有近似球形、直径100 nm左右的冠状病毒粒子，将分离鉴定的4 株IBV 定名为BJ-04、FF-04、XP-03 和YL-04。

Not only it impairs patients" genital health and Quality of life, but also is associated with an increased risk of type 2 diabetes, endometrial carcinoma, hyperlipemia, hyperpiesia, cardiovascular and cerebrovascular events. Up to now, precise pathogenesy of PCOS is yet unknown. The modern medicine indicates the etiopathogenisis of PCOS related to hereditism, endocrinology, immunology, metabolism and so on. The main features are hyperandrogenism and hyperinsulinemia, the correlation and between the above factors and how they inference PCOS are still unclear. In the view point of Traditional Chinese Medicine ,PCOS classifies to "menopathy","infertility" and "Zhengjia , its occurrence exists a close relationship with dysfunction of liver, kidney, spleen and further inducing deficiency, sputum, sluggish stagnant and fire. Many scholars insist that pathogenesis of PCOS is a renal deficiency plus phlegmatic hygrosis. However, after many years clinical observation.

随着研究的不断深入，PCOS日益显示出其复杂性和重要性；他不仅影响到患者的生殖健康及生存质量，而且其异常的激素环境使该类患者对子宫内膜癌、高血压、高血脂及心脑血管意外等病发生危险明显增加；但目前该病的确切发病机制尚不十分清楚，现代医学认为其病因涉及到遗传、内分泌、免疫、代谢等多个方面，以高雄激素血症与高胰岛素血症为主要特征，二者在PCOS发病中的确切作用，目前尚不清楚；PCOS相当于祖国医学的&月经病&&不孕&&癥瘕&等范畴，本病的发生与肝、肾、脾功能失调导致虚、痰、瘀、火有关。

Asymmetric dimethylarginine and monomethyl arginine are endogenously produced amino acids that inhibit all three isoforms of nitric oxide synthase.

点评：内皮一氧化氮以及一氧化氮合酶是目前门静脉高压症以及相关并发症的发病机制的研究热点之一，本文研究了抑制NOS的内源性氨基酸类化合物的清除酶—-二甲基精氨酸–二甲氨基水解酶，进一步的深入探究了这一发病机制，为今后治疗作用位点的选择、药物研发以及相关实验研究提供了一定的理论依据，个人认为该实验意义较大。

Injection drug use history was the main risk factor among FSWs(adjusted OR=9.8);(2) The self reported illicit drug-using behaviors and high risk sexual behaviors among close-cohort of FSWs who attended all the three cross-sectional surveys decreased accompanied with the survey time.The decrease of STIs prevalence and urine positive rate among them confirmed their decreased high risk behaviors;(3)The incidence of HIV was 1.4(95%CI 0.5～3.3)/100 Person Year in the open-cohort.FSWs who were recently HIV-infected had obvious high risk sexual behaviors with clients and 4/5 of them were not illicit-drug using FSWs;(4) 42.1%(16/38) of BED-CEIA positive specimens were false positives(＞155 days),but after eliminating the misclassified long-term HIV infected specimens,the BED-CEIA estimated HIV incidence were similar with that of the cohort survey among the same FSWs2.1/100PY vs.2.0/100PY;0.4/100PY vs.

注射吸毒行为是FSWs人群HIV感染的主要危险因素(aOR=9.8)：(2)连续参加过三次横断面调查的封闭式FSWs队列中，自报吸毒行为及高危性行为随调查时间均出现了降低的趋势，另外其性病感染率及尿吗啡阳性率的降低也印证了其自报高危行为特征的下降；(3)开放式FSWs队列中的HIV发病密度为1.4(95%CI0.5～3.3)/100人年，HIV新发感染FSWs与嫖客之间的高危性行为十分突出，以非吸毒FSWs为主(4/5)：(4)BED-CEIA阳性标本中的假阳性率为42.1%(16/38)，但在排除误检的既往HIV感染标本后，BED-CEIA及开放式队列研究估计的HIV发病密度十分接近2.1/100人年vs.2.0/100人年：0.4/100人年vs.0.6(来源：4eABC论f5f5文网www.abclunwen.com/100人年。

We also use rank sum test to analyse the differe- nce between the light pre-eclampsia group and the severe pre-eclampsia group (P=0.000),the early onset pre-eclampsia group and the late onset pre-eclampsia group (P=0.003). All of the results give the same conclude that the differences within the three groups are significant (P.05). Conclusion: We conclude that HLA-G proteins are normally expressed in invasive trophoblasts and HLA-G proteins expression is defective in most pre-eclamptic placenta.We propose that trophoblasts lacking HLA-G proteins are vulnerable to attack by the maternal immune system.

结论HLA-G分子特异性分布于胎盘EVCT的胞膜及胞浆中，生理妊娠组、子痫前期组间差异性存在表明其表达量的下降与子痫前期的发病相关；轻、重度子痫前期组间显著差异表明HLA-G分子表达量的下降与子痫前期病情严重程度相关，早发型重度子痫前期患者胎盘组织中HLA-G分子的表达明显低于迟发型组，提示我们HLA-G分子表达的降低程度还与发病早晚有关。

Dr. Spitz listed several factors that can contribute to a delay in diagnosis. He observed that some physicians expect epilepsy patients to present with grand mal seizures, that comorbid conditions such as cardiac disease and cancer can mask seizure activity, and that patients can be extremely confused for a day or two after mild seizures."The recovery period from an epileptic seizure is longer and more dramatic in someone who is 70 as opposed to someone who is seven," he said.

Spitz医师开出几项会造成诊断延误的因子，他观察到一些医师认为癫痫病患会有重癫痫的发作，comorbid的症状如心脏疾病和癌症会掩盖发作活动，病患在轻微发作后一两天会极度困惑，他表示，70岁病患癫痫症发病到复原的期间比七岁病患更长和更惊人，Spitz进一步表示，一旦被诊断出，老年病患的发病通常是轻微的，并且能用药物治疗。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。