发病的

On the establishment of shielding immune cells avoid HIV viral antigens identified protein adsorption and the establishment of "biological trap" induce HIV models Summary : HIV is the human immunodeficiency virus caused AIDS virus, AIDS is not currently be fully human control, AIDS vaccine is being developed, but because the virus genetic diversity potential to change the topic of the complexity of this ban from the incidence of HIV spread T4 cells in the mechanisms by, proposed changes T4 lymphocyte surface protein CD4 receptors structure as to avoid HIV adsorption, and the establishment of "biological trap" booby HIV idea to try to turn on AIDS treatment to the conversion of protein structure and function, as well as synthetic direction.

提要：HIV即人类免疫缺陷病毒是引起AIDS的病毒，目前爱滋病还不能被人类完全控制，AIDS的疫苗也正在研制中，但是由于病毒多样性的遗传潜能，使这一课题变的很复杂，本文试从HIV侵染T4细胞导致发病的机理入手，提出改变T4淋巴细胞表面CD4受体蛋白构象以避免HIV吸附，并设置"生物陷阱"诱杀HIV的构想，试图把对爱滋病的治疗引向对蛋白质结构与功能转化以及合成的方向。

The WHO statement goes into more detail. It says the virulence of the virus largely determines the number of severe illnesses and deaths, but many other factors influence the overall severity, including the contagiousness of the virus, the age distribution of cases, the prevalence of chronic health problems and malnutrition in a population, viral mutations, the number of waves of illness, and the quality of health services.

WHO在声明中进一步解释，病毒的毒性主要会决定重症和死亡病例的数量，但影响流感暴发严重程度的还有其他的因素，包括病毒的接触传染性、发病的年龄分布特点、是否更会在慢***和营养不良人群中流行、病毒的变异性、暴发期的次数和医疗服务的质量等。

Results 206 example patients after the stomach big excision method, including 28 people to have the complication, the complication distribution are as follows: Falls the syndrome 5 casses; The duodenum remnant end bursts 4 casses; After ulcer recrudescence, the stomach evacuation barrier, the technique obstruct, the denutrition each 3 casses; After the technique bleeds, remnant stomach cancer each 2 casses; The alkalinity returns flows gastritis, the diarrhea, lips heal fistula each 1 example.206 example patients carry on the technique effect evaluation after the Visk graduation standard, among Ⅰ Level 80 casses,Ⅱ Level 102 casses;Ⅲ Level 14 casses;Ⅳ Level 10 casses.

手术人员一方面必须非常熟悉胃十二指肠及其临近器官的正常解剖结构，并在此理论基础指导下进行手术，另一方面还必须具备扎实过硬的操作和对病人高度负责的职业态度，这样才可能尽量避免术中邻近脏器的损伤和线结被剪断，术后缝线脱落，以及减少出血等情况的发生。在施行胃大部切除术时，对切除胃的范围还没有一个精确的定量手段，只能根据临床经验进行掌握。胃切除过多，术后会导致病人胃肠功能不足，出现营养不良，甚至可以出现粒细胞减少而引起腹泻。切除胃过少又可能达不到治疗目的，出现原发病的复发，如溃疡复发，残胃癌等。

Research of ultramicro- structure of anal sphincter in the cases of patients with fecal incontinence shows : shortness of smooth muscle cells of anal sphincter , destruction of normal structure of the rest cells , elongation of elastic tissue and increase of collagen fibers. Thus the most familiar cause of copracrasia is Degeneration of finespun smooth muscle of anal sphincter which mantain anal sphincter closed .One of the pathomechanism of fecal incontinence is decrease of anal resting pressure .

对大便失禁者肛门内括约肌的超微结构研究发现：肛门内括约肌的平滑肌细胞缺失、剩余细胞的正常关系破坏、弹性组织拉伸、胶原纤维成分增加，因而大便溢漏最常见的原因是维持括约肌关闭的肌肉-肛门内括约肌的纤细平滑肌的退行性病变，肛管静息压降低是大便失禁发病的一个病理学机制。

ResultsIn 2006,German measles cases were 595,in which 484 cases were students and accounted for 81.34% of all cases;the outbreak and epidemic of German measles appeared in 5 schools;the ages of onset were most at 15-20 years old,male were more than fema...

结果2006年我县风疹共发病595例，其中学生发病484例，占发病总数的81.34%；5所学校出现风疹暴发流行；发病年龄以15～20岁最多，男性多于女性；时间集中在1～3月之间。

RESULTS: These familial keloids mainly occurred during adolescence, showing the equal chance of being affected between male and female subjects. The affected person could be heterozygous, and a child of an affected parent had a 50% chance of being affected. Thirteen subjects displayed familiar keloid, 1 suspected keloid, 2 did not present keloid as obligate carriers, and 1 did not present keloid as doubtful carrier. One pedigree displayed keloid in 3 generations, two displayed in 2 generations. The traits of familial keloids were transmitted interruptedly, revealing incomplete penetrance. The clinical phenotypes of familial keloids presented variable expression among the different affected.

结果：这些瘢痕疙瘩家系以青春期发病为主，男女患病的机会均等；杂合体即可发病，双亲之一发病其半数子女可能发病；3个瘢痕疙瘩家系发病13人，可疑发病1人，2个未发病肯定携带者，1个未发病可疑携带者；3代发病家系1个，2代发病家系2个；瘢痕疙瘩性状存在间断传递、外显不完全现象；临床表型存在个体差异。

In 1980s, HFRS additionary occurred in spring season, the diseased cases and the dead cases accounted for 42.78%and 21.73%of that of the whole year respectively, the endemic area expanded to 14 areas where the mixed infection of Hantaan virus and Seoul virus were found. In 1990s, the diseased cases and dead cases were 43.68%and 37.55%of that of the whole year respectively, mixed infection of Hantaan and Seoul virus was found.

结果表明：山东省在60年代和70年代HFRS发病以秋冬季（10月～翌年1月）为主，其发病数占全年发病数的89.87％，病死数占全年的88.99％；疫区限于6个地区，疫区型别为姬鼠型。80年代，除秋冬季发病高峰外，出现春季（3～6月）发病高峰，其发病数和病死数分别占42.78％和21.73％；疫区扩大至全省14个地区，疫区型别为姬鼠型和家鼠型的混合型。90年代情况与80年代类同，春季发病与死亡数分别占全年的43.68％和37.55％；疫区型别仍为混合型。

This subset is hyporesponsive and anergic to antigen stimulation. Recently, it has been demonstrated to participate in the immune deficiency in human immunodeficiency virus infection and has close relationship with the development of acquired immunodeficiency syndrome. Meanwhile, the CD4(superscript +)D25(superscript +)Treg is also infected when the human body is invaded by HIV. The CD4(superscript +)CD25(superscript +)Treg will finally be killed by the mechanism of antibody-dependent cell-mediated cytotoxicity. Because of the decrease of the CD4(superscript +)CD25(superscript +)Treg, it can't function as a immune suppressor as a result of the excess of activation of HIV and gradually exhausting of the T cell, which shows that the CD4(superscript +)CD25(superscript +)Treg plays a inhibitory role in the different stages of the development of the HIV as well as different effects in the pathogenesis of AIDS.

它能够抑制自身免疫病的发生和发展，参与肿瘤免疫的调节，同时在感染和移植免疫中也发挥着极其重要的作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性，新近发现它亦与爱滋病的发生、发展关系密切HIV进入人体后，CD4D25调节性T细胞抑制了机体的免疫效应但它也同时被感染，最终由于细胞毒的作用而死亡由于调节性T细胞数量的减少不能有效的发挥其抑制作用，HIV持续的过度活化使得T细胞逐渐耗竭说明在HIV发生、发展的不同阶段Treg细胞可能都发挥了免疫抑制作用，但是却对HIV感染与爱滋病发病的进程产生了不同的效应。

There is still high incidence of hepatitis A in the developping country. The wide-spread use of HAV live attenuated vaccine and inactive vaccine has provided efficient ways for controlling the epidemic of heptatitis A. while, some people got hepatitis A after injecting vaccines. In order to distinguish the viral capsid could result from hepatitis A vaccines or from natural infection, the identification of the virus strains is necessary. In 1975, KO|¨hler and Milstein have developped hybridoma technique for producting monoclonal antibody.

甲型肝炎在发展中国家多年来都有不同程度的流行，甲肝减毒活疫苗和灭活疫苗的使用，为甲肝的预防提供了可靠的手段，但偶有在接种疫苗后发生甲型肝炎的案例，这就需要对患者所感染的病原体进行鉴别，以明确患者发病的原因是接种疫苗引发还是甲肝野毒株感染导致的偶合病例。1975年KOhler和Milstein建立了杂交瘤技术制备了单克隆抗体(monoclonal antibody；McAb)。

Between women with or without endometriosis, the expression of VEGFmRNA of eutopic endometrium in the secretoiy phase was significantly higher than that in the proliferative phase(P.05). eutopic endometrium of women with endometriosis both in the proliferative phase and secretoiy phase expressed higher level VEGFmRNA than that in control group(P.05). Conclusion:①The expression of VEGF is adjusted by female'hormone.②VEGF is a very important factor that may contribute to the pathegenesis of endometriosis by promoting neovascularization,explanting of ectopic endometrium , increasing activity of angiopoiesis in eutopic endometrium③VEGF is a efficient organism maker to reflect invading growth, prognosis and metastasis potency of EMs.④VEGF may paly an important role in both pathogenesis and progress of endometriosis.

EM 患者VEGF 水平受女性性激素周期性调节；VEGF 是导致EM 发生特别是在位内膜血管活性增强、异位内膜种植、新生血管形成的重要机制，提示血管生成是EMs 发生中的一个重要因素；VEGF 可能不仅参与EM 的形成，并与进一步发展存在关系，提示血管生成在异位子宫内膜的种植、浸润中可能起着重要的病理生理作用，是EM 发病的必要环节；VEGF 是反映EM 侵袭生长、转移潜能、预后的有效生物指标，提示通过使用抗血管生成药物或抗血管生长因子抗体，来阻断血管生成，极有可能成为EM 在现有药物和手术治疗基础上的一种有效治疗策略和靶点。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。