发病机理

Objective:To study the effect of TNF α in the pathogenesis of dengue fever.

目的：研究TNFα在登革病毒发病中的作用，试图对登革病毒感染发病机理进行探讨。

ObjectsTraditional Chinese Medicine is considered that gout belong to ""bizheng"" category, whichis related to diseases of ""gout"",""severe and migratory arthralgia"",""dermatophytosis"", andso on .

研究目的祖国医学认为，痛风性关节炎属于"痹症"范畴，相当于"痛风"、"白虎历节"、"脚气"等病，对其病因及发病机制的认识、看法颇多，但其确切的发病机理尚不十分清楚，目前认为是多种因素引起的尿酸钠微结晶在关节周围组织沉积引起的急性炎症反应。

Nevertheless,as this surgical method is receiving more and more disputes,with its long-term curative effects remain further observation,it still needs ever-larger investigation.One main reason for the weak curative effects of the clinical treatment for the intractable psychopathy is the uncertainty of the pathogenesis.

难治性精神病的临床疗效欠佳，其中主要原因之一就是其发病机理还不够明确，虽然有各种环路理论和神经递质异常学说，如：由乳头体、隔区、丘脑前核、扣带回、海马、中脑被盖区、内侧嗅区构成的内侧环路功能异常学说等，但是，到目前为止，尚无任何一种学说能够完全解释精神病的发病机制。

Recently, there a break-through of traditional medical therm in therapy of stroke.

近年来中医治疗中风病有了理论上的突破，在重视传统风、火、痰、虚、瘀等发病机理的基础上，随着对传统毒邪认识的深化，逐渐认识到毒邪与中风发病密切相关，许多证据表明内生毒邪对中风病的病理及预后有直接影响。

To reseach the mechanisms of ED wtih DM from the acpects of endocrinology, morphology and molecular biology, using rats from NDM and STZ groups as control, the concentration of testosterone, LH and FSH in sera, the microstructure of testicular tissue, bulbocavernous and ischiocavernous muscle tissue, and penile cavernous tissue, the ultrastructure of penile cavernous tissue, and the expression of nNOS mRNA, the content of nNOS and eNOS, the activity of NOS and the concentration of cGMP in the pathway of LARG-NO-cGMP in penile cavernous tissue from ED rats with DM were reseached or examinated in Group A, B and C.

本实验利用第一部分所建立的DM性ED模型，采用NDM及STZ大鼠作对照，通过对A组、B组及C组DM性ED大鼠血清中睾酮、LH及FSH浓度的测定，睾丸组织形态结构的研究从内分泌方面探讨DM性ED的发病机理；通过对阴茎海绵体组织显微及超微结构和球海绵体肌及坐骨耻骨肌显微结构的研究，首次从形态学方面探讨DM性ED的发病机理；通过对阴茎海绵体组织L-ARG-NO-cGMP通路中nNOS mRNA表达、nNOS及eNOS含量、NOS活性及cGMP浓度的检测，从分子生物学方面探讨DM性ED的发病机理。

The changes of free radicals metabolism and membrane ingredients and morphology of mammary gland epithetical cells in cow suffered from Alcohol Positive Milk were studied in this paper for studying the molecular mechanism of APM/s occurring further.

为了进一步研究酒精阳性乳的发病机理，本研究从乳腺上皮细胞自由基代谢、膜组分改变和形态学变化的角度对酒精阳性乳的发病机理进行了探讨。

Although there are various etiogenic theories,the etiology and pathogenesis of endometriosis is remain obscure.

尽管关于子宫内膜异位症的发病原因学说很多，但是究其发病机理及病因学尚不明确。

The dopamine release in vivo was monitored by fast cyclic voltammetry and the concentrations of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic acid were determined by high performance liquid chromatography electrochemical detection in the process study. In addition, the effects of some traditional Chinese herbs and related marine drug on behavioral changes were also evaluated in order to provide some suggestive clue for rational drug design of anti-Parkinon's disease .

许多因素都参与PD的DA能神经元的死亡，所以，本研究在制备PD动物模型的基础上，应用国内率先引进的快速周期伏安法检测设备在体动态监测DA的释放，同时应用另一种电化学检测技术—高效液相色谱电化学检测法离体检测DA及其代谢产物二羟苯乙酸和高香草酸的含量，结合行为学测定及其它方法，研究了雌激素和铁在PD发病中的作用，以及一些药物，如吲哚醌、牛磺酸、铁离子螯合剂、胆囊收缩素（CCK-8）、乌鸡白凤丸有效成份、大豆异黄酮及海洋酸性寡糖HSH971，对DA能神经元的影响，从DA能神经递质角度对PD的发病机理提供进一步的实验依据，并为PD的预防和治疗提供新的干预措施。

Objective This study attempts to elucidate the relationship between RET oncogene and Chinese patients with Hirschsprung's disease.

目的 从分子水平探讨先天性巨结肠的发病机理，了解中国人群HD发病与酪氨酸激酶受体基因突变的关系。

Presently, the method of preventing milk fever is balancing the ion of dietary, so dietary cation anion difference comes into being.

目前，对于该病的发病机理尚没有完全搞清楚，现在多采用发病后大量补钙来进行治疗，但是在发病时，病情已十分严重，因此临床疗效常常不佳。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。