发生生物学

Agglutinative reaction of ConA to cells treated with nickel refining dusts suggested an alteration of biological feature in the attacked cells.

镍冶炼烟尘处理的细胞与ConA发生凝集意味着该细胞的生物学特征发生了改变。

After transfection with human carbonic anhydrase Ⅱ cDNA, the lovo cells changed obviously with reduction in invasiveness,chemotaxy motor ability and tolerance. Conclusion Differential expression of proteins was found between colorectal cancer genesis and hepatic metastasisnegion.

结论结直肠癌原发灶和肝转移灶蛋白质组表达有显著差异，碳酸酐酶Ⅱ表达下调和精氨酸酶、谷胱甘肽S-转移酶A3增强表达可使结直肠癌细胞生物学行为发生改变并促进肝转移发生。

In this thesis, the biology peculiarity of Galleria mellonella Linne and Achroia grisella Fabr were studied, and how to differentiate the two wax moths were summarized under amalgamating condition. Meanwhile, the biology of Apanteles galleriae Wilkinson 、 thermal threshold and thermal sum for the development、 the parasitize to various instar larvae and various host larvae and functional response to different temperature regimes were investigated.

本文对大蜡螟Galleria mellonella Linne和小蜡螟Achroia grisella Fabr的生物学特性进行了研究，并对在混合发生的情况下，如何区分两种蜡螟进行了总结；研究了两种蜡螟的主要天敌蜡螟绒茧蜂Apanteles galleriae Wilkinson的生物学特性、发育起点温度和有效积温、对不同龄期和不同寄主幼虫的寄生选择性，以及温度对蜡螟绒茧蜂功能反应的影响等。

Although the pathogenesis is not very clear, new understandings about development of pulmonary fibrosis has appeared in company with impenetration of cell biology research and molecular biology research. In a word, research of pulmonary fibrosis gradually appears to be integrated and multidisciplinary crossover.

尽管肺纤维化发病机制目前尚不完全清楚，但随着细胞生物学和分子生物学研究不断深入，对肺纤维化的发生、发展机制有了许多新得认识，肺纤维化机制的研究正逐渐走向整体化和多学科交叉方向。

Objective: The experiment will to observe: 1、the compound composed of carriers and rhBMP-2 excels or is similar to autologous iliac crest in posterolateral intertransverse spine arthrodesis in rabbits, 2、it may eliminated thd nonuions, 3、To explore the biologic process in spine arthrodesis and the role that accelaterated spine arthrodesis, 4、the roles of HA in spine fusion, by those compounds are used in posterolateral intertransverse fusion in rabbits.

目的：本实验通过rhBMP-2、HA复合物在兔子腰椎后外侧横突间融合的过程，观察了解：（1）rhBMP-2复合物在兔子腰椎后外侧横突间融合中，其作用能否优于或至少与自体髂骨相同，能否取代自体髂骨，免去取骨术。（2） rhBMP-2复合物的应用能否消除不融合的发生。（3）进一步了解脊柱融合的生物学过程，及rhBMP-2在脊柱融合生物学过程中所起的作用。（4）探讨HA在脊柱融合中的作用。

The results show that both conformations of prolyl peptide bond are not easy to transit from each other supporting the opinion that both of the BPP's bio-characters are from its conformations separately. And the function of BPP may not lie on a conformation. The other peptide bond conformations also have influence.

结果表明，脯氨酸肽键构象不易发生互变，无论哪种构象均不存在向另一种构象转变的趋势，从侧面支持了BPP具有的两种稳定的生物学作用是来自于肽键的不同构象的观点，而且BPP的生物学作用可能也不是取决于某一个肽键构象，其它脯氨酸肽键构象对其活性也存在影响。

In order to settle such predicament, the author put forward a new idea that research of TCM may be carried out as Systems biology. To take tumor as an example, tumors occur, then develop into a big one, during which experiences a multifactorial 、multifactorial processes, so Tumor Systems biology typifies holistic、kinetic、stratose and integrate characters.

文章以肿瘤系统生物学的研究思路与中医肿瘤学理论的结合点为线索，从肿瘤的发生、中医的调整阴阳的治则、现代医学的靶向治疗及肿瘤诊治的医学信息等方面为切入点对肿瘤系统生物学建立及其与中医理论结合的可行性与必要性作一初步探讨。

Gene introgression is usually resulted from spontaneous hybridization occurring among closely related species in sympatric populations and thus has great impact on genetic structure of natural populations.

同域分布的近缘物种常常发生杂交而导致种间基因渐渗，从而对相关物种的自然居群遗传结构产生重要影响，近缘种间的杂交渐渗已成为进化生物学和保护生物学关注的热点。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养，通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆；以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达，了解不同治疗阶段VEGF及其受体的表达状况，并结合临床指标进行分析，明确VEGF及其受体在白血病发生过程中的作用；流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析，初步阐明难治性白血病抗凋亡形成的原因；蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达，初步了解难治性白血病形成的分子生物学机制。

Department of Ecology and Biodiversity is primarily dedicated to education and research in ecology and biodiversity including conservation biology, coral ecology, ecotoxicology, environmental microbiology, fungal biodiversity, mangrove ecology, microbiology, molecular ecology and evolution, molecular microbial ecology, molecular phylogenetics, plant pathology, plant systematics and evolution, plant-animal interactions, pollution biology, terrestrial ecology.

生态学和生物多样性学系创建于1994年，主要致力于生态学和生物多样性学的教学与研究，其研究领域包括保护生物学，珊瑚生态学，生态毒理学，环境微生物学，真菌生物多样性，红树林生态学，微生物学，分子生态学和进化，分子微生物生态学，分子系统发生学，植物病理学，植物分类学和进化，植物－动物相互关系，污染生物学，陆生生态学等。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。