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Adverse events were similar in both groups, and the incidence of symptomatic heart failure was lower than expected among those in the trastuzumab group (less than 2%), which supports "the accumulating evidence that trastuzumab can be given concurrently with anthracyclines with a low frequency of symptomatic cardiac dysfunction, provided that low cumulative doses or less cardiotoxic anthracyclines are used, and careful cardiac monitoring is done," the authors said.

作者表示,两组的不良事件发生率相似,曲妥珠单抗组症状性心力衰竭发生率低于预期(低于2%),这支持如下观点,&越来越多的证据表明,如果应用的累积剂量较低或心毒性蒽环类药物较少且实施严密心脏监测,那么曲妥珠单抗与蒽环类药物就能够联用且所致的症状性心功能不全发生率较低。&

TaqIB polymorphism possibly contributed to cerebrocardiac vascular disease.The accidents of cardiovascular disease in B1B1 type was the highest in three genotypes while the accidents of cerebrovascular disease in B1B2 type was the highest.B2 allel gene has probably protective effect on cerebrocardiac artery.

TaqIB基因多态性与心脑血管事件发生可能有关,B1B1型心血管事件发生率较高,B1B2型脑血管事件发生率较高,B2B2型心脑血管事件发生率均较低,B2等位基因可能具有心脑血管保护作用。

The incidence of leucocytopenia was 76.9%, and the Degree Ⅲ-Ⅳ was 36.5%. The incidence of nausea and vomiting was 67.3%. The incidence of phlebophlogosis was 11.5%.

白细胞减少的发生率76.9%,其中Ⅲ-Ⅳ度达36.5%;恶心、呕吐的发生率67.3%,多为Ⅰ~Ⅱ;静脉炎的发生率11.5%。

Results: The infection rate of NI in the general hospital was 2.43%. The most frequent site of NI was lower respiratory tract (59.17%), followed by urinary tract (7.40%). Others such as gastrointestinal tract infection was 4.51% and skin-soft tissue infection was also 4.51%. The higher nosocomial infection rate was in departments of tumour, ICU, cadre ward, nosohemia. NI occurred mainly in patients with malignant tumor (7.18%), critical malignant tumor (5.97%), circulation system (3.75%).

结果:医院感染总发生率为2.43%;主要发生部位构成比中下呼吸道为最高(59.17%),其次为泌尿道(7.40%)、胃肠道(4.51%)、皮肤软组织(4.51%);各临床科室中,肿瘤科、ICU科、干部病房、血液科的医院感染发生率较高;各种类型疾病中,医院感染发生率最高为恶性肿瘤(7.15%),其次为交界恶性肿瘤(5.97%)、循环系统疾病(3.75%)。

Results The operation of treatment appendicitis perforation with diffuse peritonitis by McBurney incisions whose incisions pain disappeared quickly, intestine function recoveried fast, length of stay was short, scar was little and secluding, the complication of abdominal cavitywas residual abscess was only 0.7% higher than operation by righ middle abdomen paramedian incisions, but incisions infectious rate reduced 2.19%, pulmonary infection and pulmonary atelectasis decreased 1.50%, incisional hernia incidence rate cut down 1.50%, adhesion of intestine after operation was no difference between two groups.

结果 经麦氏切口手术治疗阑尾炎穿孔合并弥漫性腹膜炎组切口痛消失时间短,肠功能恢复快,住院时间短,疤痕小且隐蔽,在并发症中腹腔残余脓肿发生率较经右中腹旁正中切口仅高出0.70%,术后发生肠粘连无差异;而较经右中腹旁正中切口,感染率降低2.19%,肺部感染、肺不张发生率降低1.50%,切口疝发生率降低1.50%。

Negative binomial regression and polytomous Logistic regression were employed to assess the risk factors of total injuries and recurrent injuries, respectively.Results Retrospective survey of baseline showed that both groups had similar levels of injury incidence before intervention.

结果 基线分析结果显示在伤害干预措施实施之前,干预组和对照组的伤害发生水平接近,而在干预实施之后,伤害结局显示干预组和对照组的伤害发生率差异显著(P<0.001),干预组的伤害发生率比对照组的伤害发生率低10.74%。

Results:Prerenal foscial thickening was demonstrated in 94%(47/50) patients with pancreatitis,with 97.3%(36/37) in acute cases and 86.9%(11/13) in chromic patients whereas only two cases revealed left prerenal fascial thickening among 22 carcinoma patients (9.9%).

结果:胰腺炎组肾前筋膜增厚发生率94%(47/50),其中急性胰腺炎肾前筋膜增厚发生率97.3%(36/37),慢性胰腺炎肾前筋膜发生率86.9%(11/13)。胰腺癌22例中,2例肾前筋膜增厚,占9.9%,均为左侧肾前筋膜。

A dedicated doctor blind to the study was appointed to collect the indicators as follows: x-ray exposure time,Post-PCI bed-staying time,complications rates associated with puncture bleedidng, hematoma, radial pulselessness, artery-venous fistula,leg deep venous thrombosis formation,vascular access failure rates, acute LHF rates.

观察并对比如下指标:X线曝光时间,术后卧床时间,与穿刺相关的并发症发生率(出血、血肿、无脉征、动-静脉瘘等),下肢深静脉血栓形成,血管进入失败率,术后卧床期间急性左心衰的发生率,体循环及肺循环栓塞的发生率

Resultantly, the scores of the syndromes as indicated in the cancer group were higher (Qi deficiency syndrome:37.62±16.69 vs 19.92±13.36; blood stasis syndrome:28.14±9.34 vs 12.60±8.80) than those in the non-cancer group. The incidence of the syndromes in the latter group was lower (Qi deficiency syndrome :25.7% vs 67.0%; blood stasis syndrome :21.1% vs 87.0%) than the former group.The scores of the syndromes in the late cancer stage were higher than those in the early stage, but the incidences of the diagnostic patterns for the syndromes were similar. The scores of qi deficiency were higher during chemotherapy than after or without chemotherapy, those of blood stasis were similar during, after or without chemotherapy, those of the syndromes were not different with or without radiation therapy, and those of the syndromes were reduced by the two-week Traditional Chinese medicine therapy.

结果显示癌症组的气虚分数37.62±16.69比非癌症组的19.92±13.36高;癌症组的血瘀分数28.14±9.34也比非癌症组的12.60±8.80高;非癌症组气虚证的发生率25.7%比癌症组的67.0%低;非癌症组血瘀证的发生率21.1%也比癌症组的87.0%低;癌症晚期比早期有较高的气虚和血瘀分数,但证型发生率两者相似;正在化疗中的气虚分数比曾经化疗或无化疗者高,但血瘀分数则三者相似;放疗有或无不会影响癌症患者的气虚或血瘀分数;中医治疗介入两周能减少癌症患者的气虚和血瘀分数。

Results Lorcainide at concentration of 0.62mg/L,1.25mg/L and 2.50mg/L had a tendency of decreasing the incidence of arrhythmia during ischemia (P>0.05),and at 1.25mg/L and 2.50mg/L significantly decreased incidence of arrhythmia during early reperfusion (P<0.05).Its antiarrhythmic effect was accompanied with elevation of subendocardial threshold,significant abbreviation of action potential duratin in subendocardium and subepicardium,and complete or partly delay of transmural conduction time of pulses.

结果 劳卡胺分别在0.62mg/L、1.25mg/L及2.50mg/L剂量时使缺血性心律失常发生率轻度降低(P>0.05),后2种剂量使再灌注早期心律失常发生率明显降低(P<0.05);降低心律失常发生率同时可提高心内膜下心室肌兴奋阈,延长心内、外膜下心室肌细胞动作电位时程,延迟或部分延迟冲动跨壁传导时间。

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