发生处

It is found that,there are two types of interfacial cracking patterns of the ceramic coat: in the cooling process, mode Ⅰ is vulnerable to crack at the peak position of the cosine curve, and mode Ⅱ at the middle position; in the heating process, interface edges are introduced into the ceramic coat/substrate system as a result of the vertical cracks emergence, and the ceramic coat will transversely crack at these positions because of the stress concentration effect.

计算时对陶瓷层材料分别按理想线弹性本构和黏塑性本构模型开展了模拟。分析发现，陶瓷层的界面开裂存在两种模式：在降温过程中，陶瓷层容易出现界面波峰处的Ⅰ型开裂与腰部位置处的Ⅱ型开裂；在升温过程中，陶瓷层容易发生垂直开裂使结构中出现陶瓷层/基体的界面端，界面端部严重的应力集中效应使陶瓷层容易在该处横向开裂形成界面处的边裂纹。

The risk of a new adjacent vertebral fracture was 2.5-fold higher than the risk of a new nonadjacent vertebral fracture (4.03% compared with 1.59%).

结果：1226例未经药物治疗的绝后骨质疏松妇女被纳入本研究对象，在两年的随访中发现196 (16.0%)例患者出现292处新的新鲜椎体骨折，在1226例研究对象中在原椎椎体骨折邻近再发生骨折患者人数为108(8.8%)。292处新鲜椎体有136(47%)处为原椎体骨折邻近椎体再次骨折。

Reactive oxygen species causing DNA oxidative damage comes from two kinds of ways:one is from cellular normal physiological metabolism;the other is from outer environment.Redox-sensitive green fluorescent protein was expressed in Saccharomyces cerevisiae.Recombinant cells were evaluated in monitoring the changes in the redox state of living cells when challenged with toxicologically relevant metal ions NaAsO_2 or Pb(NO_3)_2 by measuring emission intensity at 510 nm with a Hitachi F6500 fluorescence spectrophotometer,roGFP expressed in yeast responded not only to typical membrane-permeant oxidants H_2O_2 and reductants DTT,but also to toxicological metal ion-induced intracellular redox changes in a dose-dependent manner.Moreover,exposure of yeast cells to NaAsO_2 or Pb(NO_3)_2 at concentrations that induced redox changes reported by roGFP caused up to 2～3 fold increases in DNA mutation frequency.This mutagenic effect was largely caused by oxidative stress since blocking the production of hydryl radicals with thiourea significantly reduced the mutation rate as well as delayed the cell death.

本文将对氧化还原状态变化敏感的绿色荧光蛋白roGFP1-R12，在酵母细胞中实现了多拷贝强表达；荧光扫描经强氧化剂H_2O_2和还原剂DTT以及环境中重金属NaAsO_2或Pb(NO_3)_2处理后的酵母细胞悬液，测定510 nm处的荧光发射强度结果显示，表达的绿色荧光蛋白对氧化还原水平敏感，且在510 nm处的荧光强度与一定的重金属浓度呈正相关，即roGFP1-R12在510nm处的荧光发射值随重金属浓度的增高而增强，从而说明重金属对细胞的毒性在一定程度上很可能是通过破坏细胞内的氧化还原平衡发生作用；同时通过该绿色荧光蛋白对胞内氧化还原状态变化的响应情况可以来实时检测环境中的重金属；遗传学的点突变频率及致死率实验数据表明，重金属能导致菌体的点突变频率和致死率升高，且活性氧的清除剂巯基脲能明显降低这种点突变和致死率，说明由重金属引发的这种点突变和致死效应在很大程度上是依赖于重金属对细胞诱导产生的氧化胁迫。

In the neighborhood of the singularities, the spectrum is redshifted at some points, and blueshifted at others.

在相位奇异点附近，一些点处的光谱发生蓝移，而另一些点处的光谱发生红移。

Each place a lightning bolt zigs or zags is where one leader stopped and another one started. Each place a lightning bolt forks is where two separate leaders formed from the bottom end of a single leader above. This whole process takes only a few thousandths of a second, but that's enough time to sculpt beautiful and complex lightning bolts.

实际上，闪电形状上不规则之处就是&先兆&发生与消逝之处，闪电&枝丫&的地方就是前一&先兆&消后产生出另外两个&先兆&的地方，尽管这一现象的发生大概不过千分之几秒，但对于形成复杂而奇异的闪电来说，已经足够了。

Based on the simulation data, the effects of clearances, damping coefficient and the rotation speed on the dynamic behaviors are studied: compared with ideal mechanisms, mechanisms with clearances are less stable; as for mechanisms with clearances, when the crank rotates at the speed of 100rad/s, the actual clearances are always above the radium of clearances, axle pin and axle cover keep contact throught the rotation; when the crank rotates at the speed of 20rad/s, mechanisms are in an unstable state, at an angle of about 300, the actual clearances are below the radium of clearances, pairs lose contact, which results in collision between them; with the speed of 20rad/s, when damping coefficient is assumed 175Ns/m, distinct separation and collision happen between pairs; when damping coefficient is assumed 220Ns/m, separation and collision are controlled.

在含间隙机构中，当曲柄以100rad/s转动时，运动副间隙始终大於半径间隙，轴销与轴套始终保持连续接触；当曲柄以低速20rad/s转动时，系统处於极不稳定的震荡状态，在转至300°左右时，运动副间隙小於半径间隙，脱离接触，发生明显的分离碰撞现象。在含间隙机构中，曲柄以低速20rad/s转动，当取法向阻尼系数为175Ns/m时，副元素发生明显的分离碰撞现象；当取法向阻尼系数为220Ns/m时控制了副元素的分离，副元素一直处於连续接触状态。

It is indicated that the easily cavitated locations are at the top of orifice, the comer at downstream of orifice and the center of the backflow.

结果显示，容易发生空化的部位主要有三处：一是孔板顶缘处，二是孔板下游角隅处，三是孔板下游回流旋涡中心部位。

A type has 7 point mutations(5 samples). B type has 6 point mutations (3 samples), C type has 4 point mutations (3 samples) and D type has 2 point mutations(1sample). Acid amino alignment shows that the most mutations of gastric cancer are mis-sense mutations, few ones are synonymous mutations. Most of the mutations occurred in regulating domain down to the HMG-box,only 2 sites in HMG-box.The mutations have same sites in middle and late stage samples. The results revealed that SOX4 mutations are associated with gastric cancer,which is possible a late accident in gastric cancer.

通过对相应的氨基酸序列的比对发现，发生在中晚期胃癌中的突变多为错义突变，同义突变不多，且突变大多发生在HMG盒下游编码区，在HMG盒内的突变只有两处，中期胃癌与晚期胃癌的突变有相同之处，但SOX4基因的突变位点随肿瘤的演进有增加的趋势。

After nail implanted and in the case of compression load, the highest effective stress occurred in the screw hole of nail (nail-screw interface) for comminuted tibial fracture. While as a complete simple fracture the highest stress presented in the outer screw-cortical bone interface.

在最大生理负载下时，一体成型的骨钉最大有效应力发生在骨折处的骨钉上，新设计的分节式骨钉则发生在骨折区域邻近处两节间的界面。

The glass layer, which is formed on the surface of the coating by the self-oxidation of the silicide, prevents oxygen from further diffusion.

试样在1700℃下氧化34h后，涂层元素与基体发生互扩散，在界面处形成大量集中孔洞，使涂层从其主体与过渡层接触的界面处发生断裂，导致涂层失效。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。