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Histone deacetylase 6(HDAC6) is microtubule and HSP90 associated protein, which control genetic transcription and change cellule motor ability by deacetylased microtubule and HSP90,and then participate tumorigenesis, growth, metabasis, and the production of tumor vessel.

研究方法: 1。应用激光捕获显微切割术联合逆转录-聚合酶链反应技术,检测36例行根治性切除的原发性肝细胞癌中心处非坏死癌组织及24例正常肝组织的HDAC6 mRNA在组织中的表达,并对HDAC6与肝癌发生发展过程中相关的临床病理因素间相关性进行研究。

The results show that maximum slump in dike nose is located within channel width of 80-100m.

计算结果表明,堤头最大坍塌发生在口门宽80~100m 的范围,该范围对应于从最深处向浅处转化的龙口水深部位。

On the contrary: the painful scene in which Catherine waits an hour for the charming Mr Tilney, only then to be whisked off by the charmless Mr Thorpe, need never have taken place had Mr Tilney just sent her a text saying "c u l8er".

相反:为了迷人的蒂尔尼,凯瑟琳足足等了一个小时,最后跟着毫无可爱之处的索普走了。若蒂尔尼能够给她发送一条"晚点儿见面"的短信,那么这痛苦的一幕就永远不会发生。

The crash happened north of Chelyabinsk , in the Urals region of Russia .

坠毁发生在距离车里雅宾斯克12公里处,属于俄罗斯的乌拉尔地区。

The crash happened 12km north of Chelyabinsk , in the Urals region of Russia .

坠毁发生在距离车里雅宾斯克12公里处,属于俄罗斯的乌拉尔地区。

In the chert bedded dolomite there are a number of ancient earthquake-tsunami relics.

在燧石条带白云岩中可见到多处古地震——海啸留下的遗迹,并见到岩壁上的几条断层,断层就是岩层受力断开发生明显位移。

Firstly, reviews the American blockbuster development the history, analyzes it from the theory and the practice to have the development inevitability, and elaborates the achievements of the American blockbuster from the cultural, artistic and commercial dimensions, and then reveals its external manifestations as an important cultural industry in the United States. Secondly, discusses choicely and emphases the successful elements of the American blockbuster: the operational ideas, marketing strategies and industry chain model, the three-parts binds into the indivisible entirety, which shows the internal motivation of its continuing development. Thirdly, analyzes our country movie's development present situation, and elaborates its exist deficiency, and inspects and analyzes the question which existed in the practice development, which will provide the theory and the practice foundation for as follows. Finally, combines the analysis and understanding of the American blockbuster in theory and the current development situation of the domestic film, it puts forward several noteworthy viewpoints about the future development of China's film industry.

首先,以考察的眼光回顾美国大片发展的历史,从理论和实践上分析其发生发展的必然性,并分别从文化、艺术、商业三个维度阐述了它所取得的成就,揭示了它作为美国重要文化工业的外部表现形态;然后,有选择有重点的论述美国大片具有的成功元素:制作中的运作理念、发行中的营销策略及其产业链模式,这三者联结成一个不可分割的整体,透析出美国大片得以不断发展的内在动因;接下来,分析了我国电影的发展现状,阐述了其存在的不足之处,考察和分析了在实践发展中存在的问题,为下文提供了理论和实践基础;最后,通过对美国大片在理论上的探析与把握,结合当下国内电影发展状况,提出了我国电影产业在未来的发展中值得注意的几点看法。

Around at 11:00 on January 7, Northern California, San Francisco, East Bay, Miao horses Das 4.1 earthquake occurred in the city, more than 40 kilometers from the city desk reporters Office is clearly felt the floor shake Under the number, and then business as usual.

一月七日上午十一时左右,北加州旧金山东湾苗匹达斯市发生四点一级地震时,距离该市四十多公里处正在书桌前的记者明显感觉到地板摇晃数下,随后一切如常。

Typical bands were used to analyze relation with ecotypes and characters of fruits, indicating that there was no relation between typical bands and ecotypes, but some extent relation between bands and characters of fruits existed. If all cultivars were divided into freestone and clingstone, melting and nonmelting, both freestone (ratio shared total survey, 41/56=73.2%) and clingstone (ratio shared total survey, 33/79=41.8%) appeared in the loci of S_(167)-1050 bp linked marker raised by Warburton et al. It was apparently not strong linkage between the marker and the character, and exchange rate of genes was high. If combinations of S_(167)-850bp and S_(167)-1050bp or S_(167)-850bp and S_(167)-1400bp were used to distinguish characters of fruits, 6 freestone accessions without clingstone ones and 6 melting accessions without nonmelting ones displayed in the first combination of markers, 20 clingstone accessions and 2 semi-freestone ones without freestone ones appeared in the second combination of markers.

通过典型带对不同生态型、果实性状为类别进行分析,结果未发现有与生态型相吻合的特征带出现,而将供试所有品种按离核、粘核和溶质、不溶质划分归类,供试品种在Warburton等得到S_(167)-1050 bp处粘离核分子标记,出现既有离核(占供试离核41/56=73.2%),又有粘核(占供试粘核33/79=41.8%),可见此连锁标记连锁性不强,发生交换的机率较高,而S_(167)-850bp带和S_(167)-1050bp带同时出现时,该组包含6个离核,无粘核品种;6个溶质,而无不溶质。S_(167)-850bp和S_(167)-1400bp同时出现时,包含20个粘核品种和2个半离核品种。

The mitral-valve tenting area was also measured and used as a quantitative index for leaflet stiffening and apical displacement of leaflet coaptation.

对二尖瓣幕状区也进行测量,作为定量参数评价发生瓣叶僵硬和瓣叶接合处顶部移位。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。