发生中的

We have found that there are regularity changes in the Raman spectra of grossular-andradite as the rise of iron in the crystal structure from grossular to andradite after studying of Raman spectra of grossular-andradite, that is to say, their peaks shift to low wavenumber; At the same time , there are some changes in the bond angles of O-Si-O and O-Y-O:the higher of iron contents, the evidenter of splitting of two wind vibration peaks of SiO4 tetrahedron and YO6 octahedron.

通过对钙铝榴石-钙铁榴石的拉曼光谱研究发现，从钙铝榴石到钙铁榴石，随着矿物结构中铁的含量的增加，他们的拉曼光发生规律性的变化，即所有的峰向低波数方向发生漂移；同时，由于铁含量的不同使得石榴石晶体结构中O-Si-O与O-Y-O之间的键角发生了一定的变化，在其拉曼光谱谱图上表现为铁的含量越高，[SiO4]四面体和Y-O八面体的两个弯曲振动峰分裂得越明显。

To investigate whether the expression of cdc2 and cyclin B1 in spermatogenic cells during spermatogenesis is actually a temperature dependent event, in situ hybridization, Western blotting and immunohistochemistry analysis were used to study the expression of cdc2 and cyclin B1 in normal and cryptorchid testis. Results showed that heat would differentially hurt male germ cells in different developmental stages during spermatogenesis, especially the pachytene primary spermatocytes. Most of spermatogonia in contralateral cryptorchid testis were not harmed fatally by heat as yet, indicating that spermatogonia could resist to beat to a certain extent. In this case spermatogonia could develop to pachytene/diplotene primary spermatocytes, but they could not acquire the ability to complete the transition from mitosis to meiosis, and then appeared to go through apoptosis. Therefore, we could not find the descendants of meiosis: secondary spermatocytes and round spermatids, elongated spermatids and spermatozoon. The abdominal temperature had no significant influence on the transcription of cdc2 and cyclin B1 in the spermatogonia and pachytene/diplotene primary spermatocytes. In normal rabbit testis, cyclin B1 increased in the pachytene/diplotene primary spermatocytes before meiosis and reached its peak in the spermatids.

为了解精子正常发生过程中cdc2和cyclin B1表达的低温依赖性，我们利用原位杂交和免疫组化等方法，研究了正常和隐睾精子发生过程中cdc2和cyclin B1的转录和翻译调控活动，结果表明：（1）热对各阶段的雄性生殖细胞都有损害，粗线期的初级精母细胞尤为敏感，实验性隐睾内的精原细胞尚未完全受到"致命"影响，说明精原细胞对热有一定的耐受性，但即使成为粗线期／双线期初级精母细胞，却未能获得由有丝分裂过渡到减数分裂的能力，呈现不同程度的凋亡，所以在整个切片中找不到源自减数分裂的产物----次级精母细胞、圆形精子细胞，更谈不上长形精子细胞和精子的形成；（2）腹腔高温未明显地影响隐睾精原细胞和粗线期/双线期初级精母细胞中cyclinB1和cdc2的转录，说明高温并不是通过影响cyclin B1和cdc2的转录活动而导致生精过程阻断的；（3）正常兔睾丸组织中，〓在精原细胞和粗线期／双线期精母细胞中均有表达：cyclin B1蛋白在减数分裂前期的粗线期／双线期初级精母细胞中的表达量增加，于变态末期的精子细胞中达高峰。

2Nd, thorough analysis: The Earth may say is an extremely marvelous thermonuclear reactor, when the earth interior pressure achieved certain critical, in the Earth material may decay the nuclear matter is called as the thermonuclear material, can have the thermonuclear reaction, thus has the huge energy, then the melted partial materials, form the rock magma are the liquid state materials, this response stratification plane is possibly many stratification planes, first possibly is located between the earth's crust and the mantle, upward next two transfers, displays for the light density material diastrophism as well as density upper mantle material phenomena and so on solidification; Under second possibly is located between the mantle and the core, the pressure is more formidable, causes not not easily to have the thermonuclear reaction thermonuclear material to have the response, forms the relative quite stable liquefied material level, simultaneously is upward next two transfers, forms the counter-flow phenomenon which the high density under mantle as well as the high density core material contact liquefies and is far away cools; These material periodicity regular movements and so on convection as well as Earth polar axis rotation are possibly the basic source powers which the terrestrial magnetic field produces.

深入剖析：地球可以说是一个非常奇妙的热核反应堆，当地球内部的压力达到一定的临界，地球物质中可衰变的核物质统称为热核物质，就会发生热核反应，从而产生巨大的能量，进而融化部分物质，形成岩浆即液态物质，这个反应层面可能是多个层面，第一层可能位于地壳与地幔之间，向上下两边对流，表现为轻密度物质的地壳运动以及中密度上地幔物质的固化等现象；第二层可能位于下地幔与地核之间，压力更为强大，引起不易发生热核反应的热核物质发生反应，形成相对比较稳定的液化物质层，同时向上下两边对流，形成中高密度的下地幔以及高密度地核物质的接触液化和远离冷却的对流现象；这些对流以及地球极轴自转等物质周期性规律性运动可能是地球磁场产生的根本源动力。

Morphological and flourescent changes were assessed using confocal microscopy in whole-mount organ of Corti preparations. Results (1) After the animals were exposed to broadband noise at 122 dB SPL in 4 h/day for 2 days, both apoptosis and necrosis appeared in OHCs. The single strand DNA in apoptotic OHCs were observed both in guinea pigs and mice.(2) In normal OHCs, EndoG was distributed outside of nuclei. EndoG translocated from outside to inside of the nuclei in both apoptotic and necrotic OHCs following noise exposure.(3) The MNNG cochlear perfusion and noise exposure both caused the transloctation of AIF from the mitochondria to the nuclei. The translocation of AIF took place in both apoptotic and necrotic OHCs.

结果 (1)暴露于120 dB SPL的白噪声环境中每天4小时，连续2天后引起豚鼠和小鼠耳蜗外毛细胞凋亡时，其细胞核内产生ssDNA，而在正常细胞内没有三ssDNA；（2）在正常情况下，EndoG分布于耳蜗毛细胞的细胞核外，在暴露于上述噪声后发生凋亡和坏死的豚鼠耳蜗外毛细胞中，EndoG从细胞核外转移到细胞核内，细胞核中的EndoG显著增加；（3）豚鼠耳蜗外淋巴灌流烷化剂MNNG后发生耳蜗外毛细胞凋亡和坏死，在凋亡和坏死的耳蜗外毛细胞中，AIF自线粒体转移到细胞核，其变化与噪声损伤引起耳蜗外毛细胞凋亡和坏死时一致。

First, we made a model of exhaustive exercise in rats, and used sucessfully the model in this study. We studied the effects of exhaustive exercise on adhesive behaviour of leukocytes in mesenteric venules by using an intravital microscope video system Its results indicated that the adhesiveness of circulating leukocytes to mesenteric venules enhanced after exhaustive exercise in rats.

首先，本文以游泳方法建立了大鼠模拟运动力竭模型，并成功地将此模型运用到本研究中；设计制作了肠系膜固定有机玻璃板，组成了一套活体显微观察实验系统；研究了大鼠运动力竭前后肠系膜微循环中白细胞粘附行为，结果表明：大鼠运动力竭后肠系膜微循环血流流态发生了明显的改变，大鼠运动力竭后肠系膜微循环中白细胞粘附性增强、白细胞滚动速率降低、在体白细胞变形性减小，将影响微循环正常的灌注，是导致微循环障碍发生发展的一个重要原因，进而最终表现为机体运动能力和运动质量下降。

Take DMSO swollen treatment and DEA-SO2-DMSO decrystallization treatment for example, the X-ray diffraction and the Tobolsky's intermittent stress relaxation of treated woods were determined during soaking in water, analyzed the effects of water on crystal degree and inter-cohesion of treated woods. According to these continuous relaxation curves measured in water with different temperatures, various thermodynamic quantities were obtained by using Eyring absolute rate theory, and reviewed the chemical reactions in wood which occur in different relaxation process. For the first time quantify these crosslinkings formed in the process of tensional relaxation by using the SMCIR intermittent stress relaxation way, and defined the cross-linking reaction types. In order to find out the contribute of drying to the fixation of deformation of chemically treated wood, stress relaxation of oven-dry untreated and treated wood was measured during the process of temperature elevation and descend, then analyzed the effect of temperature change on relaxation mechanism of treated oven-dry wood. According to continuous relaxation curves of oven-dry treated wood under various constant temperature, calculated the thermodynamics of relaxation process and discussed the mechanism of molecule change in wood, at the same time, also quantified these cross-linkings produced in wood by intermittent method and on the basis of which the model of molecular change during relaxation process of chemically treated was constructed.

以DMSO膨胀处理及DEA- SO2-DMSO非晶化塑化处理为例，测定了两种处理木材在水浸渍过程中的X射线衍射及Tobolsky间歇应力松弛，分析了水对处理木材结晶度及内部凝聚力的影响；通过未处理和两种处理木材在不同温度水中的连续应力松弛测定，应用Eyring的绝对速度反应理论计算并获得了松弛过程中的各热力学量，分析了在水中松弛过程中不同阶段木材内部发生的化学反应；并首次采用SMCIR连续·不连续双曲线应力松弛法定量了轴向拉伸应力松弛过程中木材内部产生的架桥量，明确了交联反应的类型；为了了解干燥对处理木材塑性变形固定的影响，测定了未处理和两种处理绝干木材在温度下降过程和上升过程中的应力松弛，分析了温度变化对处理绝干木材应力松弛的影响；根据多个温度水平下的连续应力松弛测定曲线，计算松弛过程的热力学量，考察了绝干木材在松弛过程中内部发生的分子变化机理，同时也用间歇法定量了木材内部新形成的架桥量，并在此基础上构筑处理木材在松弛过程中内部分子构造的变化模型。

The risk factors of breast carcinoma includes family history (The likelihood of developing breast cancer for a patient, if one of whose mother or sisters does, will increase by 1.5 to 3 times.), age, BMI, hereditary factors (The risk of developing breast cancer for a female whose BRCA1 gene has been mutated reaches 50-85% in her life.), female, contact history of the endogenous and exogenous estrogen, past history of chest being exposed to the radiation, dietary pattern, benign mastopathy and environmental factors.

发生乳腺肿瘤的危险因素包括：家族史（假如患者母亲或姐妹当中有一人发生乳腺癌，该患者乳腺癌发生的可能性增加1.5至3倍），年龄，肥胖，遗传性素因（BRCA1基因突变的女性一生中发生乳腺癌的可能性为50－85％），女性性别，内源性和外源性雌性激素接触，既往有过胸部放射性暴露史，膳食结构，良性乳腺疾病和环境因素。

All the LOH on 〓 and 〓 was observed in invasive ductal carcino- ma, carcinoma simplex, medulary carcinoma and scirrhous carcino- ma, no deletions at these sites were observed in any invasive lobular carcinoma and others. These results imply an etiological difference.P53 gene is a hot point gene in the occurrence and development of breast, cancer. PCR-SSCP analysis was performed to detect P53 gene point mutation in the region between exon 5 and 8, 5 of 12 (41. 6%) stage I breast cancer patients contain mutation of P53, 3 of 5 patients were accompanied by 〓 deletion. These results suggested that point mutation and allelic loss of P53 gene are two vi- tal genetic events in earlier stage of breast tumorigenesis.

我们还发现，〓和〓位点LOH均分布在乳腺浸润性导管癌、单纯癌、髓样癌及硬癌中，在浸润性小叶癌和某些特殊类型乳腺癌中全部为LOH阴性，上述位点LOH可能与某些组织学类型乳腺癌的发生有关。P53基因是乳腺癌形成过程中的一个热点基因，本研究对12例Ⅰ期乳腺癌组织标本中P53基因热点区域第5、6、7、8外显子点突变进行了测定，发现41.6％（5／12）的病人有P53基因一个或多个点突变，其中3例同时伴有〓位点LOH，表明P53基因点突变和等位基因缺失是发生在乳腺癌形成早期的一个重要遗传学事件。

Although Pygo expressed ubiquitously in the embryo, it expressed at relatively high level in pre-blastoderm embryos which indicated a high degree of maternally provided message, followed by a low level of ubiquitous zygotic expression.

结果表明，虽然pygo普遍表达于整个胚胎中，并且在果蝇胚胎发生全过程都有，但Pygo在前囊胚层(pre-blastoderm)中的表达水平相对较高，这说明胚胎发生过程中来自母方的贡献较高。

Objective:The aim of the experiment is to search for the regulation that the hepatic stem cells abnormally differentiate into cancer cells. In the experiment,the variating regulation of PCNA,c-kit and c-myc in the formation and development of HCC will be interpreted with immunohistochemistry and RT-PCR. So,the initial mechanism that hepatic stem cells abnormally differentiate into cancer cells from the levels of cell,protein and gene will be clarified. The last,the inhibition to HCC with ulinastain will be studied,from which,a new way of clinical prevention and treatment for HCC will expect to be explored.

二、目的本实验旨在探讨以卵圆细胞为代表的肝干细胞在HCC发生、发展过程中在肝组织内分布规律，并通过免疫组化、RT-PCR等技术阐明PCNA、c-kit、c-myc在HCC发生、发展过程中的动态演变规律，从细胞、蛋白、基因三个水平初步研究卵圆细胞向癌细胞异常分化的机制，同时观察乌司他丁对HCC发生、发展的抑制作用，为肝癌的临床预防和治疗探索新的途径。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。