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In our study, we found menadione has anticancer potential on human breast adenocarcinoma MDA MB 231 by weather cell cycle arrest, anti proliferation, or apoptosis. Low concentration of menadione (5.8μM) significant inhibited growth curve on breast cancer cells (MDA MB 231) but not breast cells (MCF 10A) by performing MTT and trypan blue cell counting. RT-PCR and western blotting showed menadione increase p21 gene and protein expressions but decrease cyclin E and CDK2 protein expression resulting in cell cycle G0/G1 arrest by flow cytometry.

MTT及生长曲线的实验,发现menadione在低浓度且长时间作用情况下,对在於人类乳腺上皮细胞癌(MDA-MB 231)是有明显的抑制作用,而在正常乳腺细胞(MCF-10A)则没有影响,在分子转录上及蛋白质表现方面也发现低浓度menadione处理24时能使MDA-MB 231诱发p21基因及蛋白表现量增加及cyclin E、CDK2抑制,再经由流式细胞仪分析也发现低浓度 menadione 处理24小时能使MDA-MB 231细胞周期GO/G1比例上升,造成细胞周期停滞,进而抑制细胞生长。

Gansu has never been found in past reports of fossil porcupine from Linxia basin Pliocene porcupines found in fossils of such animals is first found in Gansu, which will not only expand the hedgehog distribution in China, but also for the Asian Neogene Evolution of hedgehog provided important information.

甘肃过去从未有发现豪猪化石的报导,从临夏盆地中新统中发现的豪猪化石,是这类动物在甘肃的首次发现,这不但扩大了豪猪在我国的分布范围,也为亚洲新近纪豪猪的演化提供了重要信息。

"This is an exciting discovery because it extends the time range for liquid water on Mars, and the places where it might have supported life," said CRISM principal investigator Scott Murchie of the Johns Hopkins Applied Physics Laboratory in Laurel, Md. The identification of opaline silica tells us that water may have existed as recently as 2 billion years ago.

" "这是个令人兴奋的发现,因为该发现延长了水在火星上的存在时间,也扩大了可能支持生命存在的范围,"专用小型侦察影像频谱仪的主要研究人员、马里兰州劳瑞尔市约翰霍普金斯应用物理实验室的斯科特·默基说,"蛋白石硅酸盐的发现使我们可以断定:仅仅20亿年前,火星上仍有水存在。

Because the last confirmed sighting of an ivory-bill was in Louisiana in 1944, the Arkansas "discovery" was hailed at the time as the ornithological equivalent of finding Elvis alive, and the event catapulted the birds to celebrity status.

因为最后一次被确认的关于象牙喙啄木鸟的发现是在1944年的路易斯安娜州。所以阿肯色州的"发现"不啻于发现"猫王"复活。那次事件让这种鸟名声大噪。

Marie Curie, a famous scientist, also has set a good example. In 1898, Marie found a new element in the pitchblende. In order to improve her discovery, Marie and her husband worked hard. At last they saw the dim blue light of new element ——radium.

玛丽·居里,一位著名的科学家,也给我们树立了典范。1898年,居里夫人在铀矿里发现了新元素,为了证明她的发现,居里和她的丈夫努力钻研,最后他们终于看见了镭的蓝光,发现了新元素。

Results 1 week af ter injection , the average diameter of tumors ineach test group decreased when compared with the cont rol group. In 100 % acetic acid2group , only 1case had renascent tumors near the necrosis focus.

结果 注射后一周各实验组肿瘤直径均减小,对照组肿瘤直径明显增大。100 %乙酸组10 例仅1 例在坏死灶周围发现新生灶,而50 %乙酸组发现5例,75 %乙酸组发现7 例。

Well, if you very value Avalokitesvara, and if you begin to see, even a little bit, that actually this worldly life has not too much value, like that Sadhu, but actually, I mean not even like that Sadhu, just you know every day maybe just a moment or two thinking that the worldly has not too much essence.

那么如果你非常看重观世音菩萨,如果你开始发现——哪怕仅是发现了一点点——事实上世俗的生活并非那么有价值,就像那位萨度所发现的那样。

According to Xinhua News Agency, Hohhot, December 2 -, as far as dinosaurs鄂托克旗Geosites Regulatory Commission Office of introduction, experts in national鄂托克旗Geosites protection zone fossils point 15 carried out a detailed inspection , with the exception of Allactaga discovered well-preserved fossils of dinosaur footprints of mold, but also discovered a new fossil bird footprints, and the Jurassic in the local surface for the first time found that type of animal feet, sauropod dinosaur footprint fossils.

据新华社呼和浩特12月2日-,据鄂托克旗恐龙地质遗迹管理委员会办公室介绍,在国家鄂托克旗地质遗迹保护区,化石点,详细检查了15名专家进行的,与发现异常的跳保存完好的恐龙脚印化石的模具,而且还发现了一种新的鸟类足迹化石,以及在第一次当地的地表侏罗纪发现,动物的脚型,蜥脚类恐龙足迹化石。

After the disease, he can order for themselves to live down on this desert island, they wanted to further understanding of the island, so he started the adventure on the island, he found that can not eat the sour grape, and he wanted them to into raisins, found birds,He thought of raising them, he found野山羊, it immediately thought of the trap can be done to seize them.

在病好之后,他为了让自己能够在这个荒岛上住下来,于是就想进一步的了解这个岛,所以他便开始了岛上历险,他发现了酸葡萄不能吃,于是他就想把它们做成葡萄干,发现了飞禽,他就想到驯养它们,他又发现了野山羊,就立马想到可以做陷阱抓住它们。

Liberty Media completed its spinoff of its 50% stake in Discovery Communications , owner of Discovery Channel , TLC and Animal Planet .

自由媒体已经出售了它在发现通信的50%控股,发现通信拥有的资产包括发现频道, TLC 和 Animal Planet 。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。