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E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果,本论文首次提出以下论点:(1)ACTH在脊髓水平对抗阿片镇痛具有受体选择性,即ACTH可对抗μ受体和δ受体介导的镇痛,不对抗κ受体所介导的镇痛;(2)由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力,与μ受体的非肽类配体的结合位点以及δ受体无亲和力,推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的;(3)ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用;(4)ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应;(5)通过Fos蛋白的诱导揭示:ACTH可以作用于脑内多个核团,其中包括许多与痛觉调制有关的核团,推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

The small and medium-sized enterprise should display the imbark spirit, the display development product creativity, how attentively studies well detains the talented person.

中小企业应发挥创业精神、发挥开发产品的创意,好好用心研究如何留住人才。

TSPG has the similar effect as HGFs, can directly or/and indirected effect and regulate proliferation and differentiation of CD34〓 HSC/HPC to bring into full play in"invigorating qi"of Panax ginseng. 2. During the process of the extensive proliferation, orderly differentiation, functional activation and gene transfer of hematopoietic stem/progenitor cells in ex vivo culture systems, TSPG may be used to regulate the proliferation and differentiation of hematopoietic cells to perform potential application in the domain of hematpoietic stem cell engineering.

我们的研究结果提示:1、TSPG具有类似造血生长因子的功效,能直接或间接影响和调控造血干/祖细胞的增殖与分化,促进血细胞的生成,从而发挥人参&补气生血&之功效。2、在进行对造血干/祖细胞的扩增与诱导分化,功能激活,基因转染等造血干细胞工程研究中可利用人参皂甙的药理作用来调控细胞的增殖分化,发挥其在造血干细胞工程领域的潜在应用价值。

Only Lamin A was observed to be able to be co-immunoprecipitated with 8B7 spectrin.Lamin A is a component in lamin and functions as a common anchoring site for many proteins.It plays important roles in maintaining normal morphology of nuclear envelope,presenting anchoring site for chromatin and reconstructing of nucleus.8B7 spectrin may function through interaction with Lamin A.

Lamin A是核纤层的组成成分,由LMNA基因编码,是核内许多蛋白分子的共同锚定物,在维持核膜的正常形态,提供染色质的锚定位点以及在核的重组过程中可能发挥重要作用。8B7血影蛋白可能经由Lamin A发挥功能。

Under our socialist market economy, we should insist on this mode in developing the chambers of commerce: hosting by non-governmental organizations, supporting by government, and leadin...

在完善商会功能的问题上,应重点发挥服务与管理功能,充分发挥商会在发展社会主义市场经济中的积极作用。

When applying monose that was easily utilized by HPB as substrate, the competition for common feed among different populations restrain their exertion of co-metabolism. While applying complex organic compounds including greese, ester and protein as substrate, the co-metabolism among different populations could be exerted and therefore the hydrogen-producing ability of HPB was enhanced via their cooperation.

以单糖为底物时,由于菌种间的竞争作用,抑制了高效HPFB的产氢能力,混合菌种协同作用不能有效地发挥;以复杂的有机物为底物时,菌种间的共代谢协同作用是可能积极地发挥,进而提高高效HPB的产氢能力。

Ferrell played as well as he was allowed to, but Nevel simply overwhelmed him with ridiculous firepower and air-tight safety play.

费雷尔发挥,以及他被允许,但nevel只是压倒了他与荒谬的火力和空中严密的安全发挥

These findings are consistent with the previous knowledge that IGF-2 is mainly expressed during the embryonic phase, IGF-1 is mainly expressed during the postnatal period, which could promote cell proliferation and ontogenesis.

这与IGF-2主要在胚胎期发挥作用,而IGF-1则主要在动物个体出生后才发挥促进细胞增殖和个体发育功能的特点相符。

For this, should establish a program as soon as possible, establish harmonious organization, industry of region of integrated edge overbridge and resource, better the main cohesive force austral play and radiant emitance, strengthening international communicates and carry out western bigger effect is produced in developing the strategy greatly.

为此,应尽快制定规划、成立协调组织,整合沿陆桥地区产业和资源,更好地发挥南干线的内聚力和辐射力,在加强国际交流和实施西部大开发战略中发挥更大作用。

The basic function of county government is to perfect the configuration of market economy system to create basic conditions for the performance of market system by institutional innovation; the guiding function refers to the one that county government creates the development plans, strategies, policies and economic levers to promote the agricultural modernization, county industrialization,and urbanization for driving the county developmant; organizational function means that county government carries out the correct measures of industrial organization to avoid infavorable impact of overcompetition on economy and to improve the development and competitivity; regulatory function performs when county government regulates the conducts of market bodies by economic, legislative and administrative means to solve the externality and to sustain the development; and the complementory function acts on market by government supplying the public goods and harmonizing the social development.

基础性作用即县级政府通过一系列市场化的制度创新,建立完善了市场经济体制的基本框架,为市场机制发挥作用创造了基础条件;主导性作用即县级政府通过发展规划、发展战略、经济政策和经济杠杆,促进农业现代化、县域工业化和城镇化,使县域经济发展更具主动性;组织性作用即县级政府实施正确的产业组织措施,克服过度竞争对县域经济发展的不利影响,提高县域经济运行质量和竞争力;矫正性作用即县级政府通过一系列经济、法律、行政手段,对市场主体的行为进行调节,解决县域经济的外部性问题,使县域经济提高效率,实现可持续发展;补充性作用即县级政府发挥对市场的补充作用,主导公共产品供给,从根本上解决县域公共产品短缺问题,实现经济社会协调发展。

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推荐网络例句

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时,滚道或滚动元件褪色是很常见的特征。

The lawyer's case blew up because he had no proof.

律师的辩护失败,因为他没有证据。